A quantitative analysis of antipsychotic prescribing trends for the treatment of schizophrenia in England and Wales

Rossela Roberts, Abigail Neasham, Chania Lambrinudi, Ashan Khan

    Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

    241 Wedi eu Llwytho i Lawr (Pure)

    Crynodeb

    Objective
    This study aims to assess the current antipsychotic prescribing trends for the treatment of schizophrenia and to compare them with available guidelines and research evidence.

    Design
    An observational retrospective quantitative analysis.

    Setting
    Data were collected from the prescribing cost analysis for the period between 2007 and 2014, including all drugs from the British National Formulary 4.2.1 and 4.2.2. Prescriptions were included from primary and secondary healthcare settings in England and Wales.

    Main outcome measures
    Defined daily doses of antipsychotics were used to compare popularity of individual drugs and classes of antipsychotics.

    Results
    There is a consistent increase in the proportion of atypical antipsychotics prescribed, compared to typical antipsychotics, between 2007 and 2014, with atypicals accounting for 79.9% of total antipsychotics prescribed in 2014.

    Conclusion
    The consistent popularity of atypical antipsychotics is not concordant with the current National Institute for Health and Care Excellence guidelines for the treatment of schizophrenia or the most recent research evidence.
    Iaith wreiddiolSaesneg
    CyfnodolynJournal of the Royal Society of Medicine
    Cyfrol9
    Rhif cyhoeddi4
    Dyddiad ar-lein cynnar1 Ebr 2018
    Dynodwyr Gwrthrych Digidol (DOIs)
    StatwsCyhoeddwyd - 18 Ebr 2018

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