Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

Ali Kermanizadeh; Trine Berthing; Ewa Guzniczak; Melanie Wheeldon; Graeme Whyte; Ulla Vogel; Wolfgang Moritz; Vicki Stone

doi:10.1186/s12989-019-0326-0

Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

Ali Kermanizadeh
, Trine Berthing
, Ewa Guzniczak
, Melanie Wheeldon
, Graeme Whyte
, Ulla Vogel
, Wolfgang Moritz
, Vicki Stone

Heriot-Watt University, Edinburgh
National Research Centre for the Working Environment, Copenhagen
InSphero AG, Schlieren

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

27 Wedi eu Llwytho i Lawr (Pure)

Iaith wreiddiol	Saesneg
Rhif yr erthygl	42
Cyfnodolyn	Particle and fibre toxicology
Cyfrol	16
Rhif cyhoeddi	1
Dyddiad ar-lein cynnar	19 Tach 2019
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1186/s12989-019-0326-0
Statws	Cyhoeddwyd - 19 Tach 2019
Cyhoeddwyd yn allanol	Ie

Mynediad at Ddogfen

10.1186/s12989-019-0326-0Trwydded: CC BY

2020 Assessment of nanomaterialFersiwn derfynol wedi’i chyhoeddi, 1.95 MBTrwydded: CC BY

Ôl bys

Gweld gwybodaeth am bynciau ymchwil 'Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

Dyfynnu hyn

Kermanizadeh, A., Berthing, T., Guzniczak, E., Wheeldon, M., Whyte, G., Vogel, U., Moritz, W., & Stone, V. (2019). Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate. Particle and fibre toxicology, 16(1), erthygl 42. https://doi.org/10.1186/s12989-019-0326-0

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title = "Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate",

keywords = "3D primary human multi-cellular liver microtissue, In vitro hepatotoxicology, In vitro vs, Kupffer cells, in vivo comparisons",

author = "Ali Kermanizadeh and Trine Berthing and Ewa Guzniczak and Melanie Wheeldon and Graeme Whyte and Ulla Vogel and Wolfgang Moritz and Vicki Stone",

year = "2019",

month = nov,

day = "19",

doi = "10.1186/s12989-019-0326-0",

language = "English",

volume = "16",

journal = "Particle and fibre toxicology",

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Kermanizadeh, A, Berthing, T, Guzniczak, E, Wheeldon, M, Whyte, G, Vogel, U, Moritz, W & Stone, V 2019, 'Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate', Particle and fibre toxicology, cyfrol. 16, rhif 1, 42. https://doi.org/10.1186/s12989-019-0326-0

Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate. / Kermanizadeh, Ali; Berthing, Trine; Guzniczak, Ewa et al.
Yn: Particle and fibre toxicology, Cyfrol 16, Rhif 1, 42, 19.11.2019.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

TY - JOUR

T1 - Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

AU - Kermanizadeh, Ali

AU - Berthing, Trine

AU - Guzniczak, Ewa

AU - Wheeldon, Melanie

AU - Whyte, Graeme

AU - Vogel, Ulla

AU - Moritz, Wolfgang

AU - Stone, Vicki

PY - 2019/11/19

Y1 - 2019/11/19

KW - 3D primary human multi-cellular liver microtissue

KW - In vitro hepatotoxicology

KW - In vitro vs

KW - Kupffer cells

KW - in vivo comparisons

U2 - 10.1186/s12989-019-0326-0

DO - 10.1186/s12989-019-0326-0

M3 - Article

C2 - 31739797

SN - 1743-8977

VL - 16

JO - Particle and fibre toxicology

JF - Particle and fibre toxicology

IS - 1

M1 - 42

ER -

Kermanizadeh A, Berthing T, Guzniczak E, Wheeldon M, Whyte G, Vogel U et al. Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate. Particle and fibre toxicology. 2019 Tach 19;16(1):42. Epub 2019 Tach 19. doi: 10.1186/s12989-019-0326-0