Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

Paul G Mullins; David J McGonigle; Ruth L O'Gorman; Nicolaas A J Puts; Rishma Vidyasagar; C John Evans; Richard A E Edden; Cardiff Symposium on MRS of GABA

doi:10.1016/j.neuroimage.2012.12.004

Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

Paul G Mullins
, David J McGonigle
, Ruth L O'Gorman
, Nicolaas A J Puts
, Rishma Vidyasagar
, C John Evans
, Richard A E Edden
, Cardiff Symposium on MRS of GABA

School of Healthcare Sciences, Cardiff University
University Children's Hospital, Zurich
University of Zurich
Johns Hopkins University
Kennedy Krieger Institute
Manchester University

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	43-52
Nifer y tudalennau	10
Cyfnodolyn	Neuroimage
Cyfrol	86
Dyddiad ar-lein cynnar	13 Rhag 2012
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/j.neuroimage.2012.12.004
Statws	Cyhoeddwyd - 1 Chwef 2014

Mynediad at Ddogfen

10.1016/j.neuroimage.2012.12.004

Editing School
Mullins, P. (Siaradwr)
3 Rhag 2018 → 6 Rhag 2018
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Mullins, P. (Rheolwr), Binney, R. (Arall), Bestelmeyer, P. (Arall), Downing, P. (Arall), Kornysheva, E. (Arall), Valyear, K. (Arall), Koldewyn, K. (Arall), Ramsey, R. (Arall), d'Avossa, G. (Arall), Carey, D. (Arall), Henderson, R. (Arall), Rossetti, G. (Arall), Oliver, S. (Arall) & Macdonald, J. (Arall)
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@article{64bb031a87a94cf0ab7776ddb79268cd,

title = "Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA",

abstract = "There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current {\textquoteleft}state-of-the-art{\textquoteright} in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.",

keywords = "Algorithms, Brain, Humans, Magnetic Resonance Spectroscopy, Reproducibility of Results, Sensitivity and Specificity, gamma-Aminobutyric Acid, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review",

author = "Mullins, \{Paul G\} and McGonigle, \{David J\} and O'Gorman, \{Ruth L\} and Puts, \{Nicolaas A J\} and Rishma Vidyasagar and Evans, \{C John\} and Edden, \{Richard A E\} and \{Cardiff Symposium on MRS of GABA\}",

year = "2014",

month = feb,

day = "1",

doi = "10.1016/j.neuroimage.2012.12.004",

language = "English",

volume = "86",

pages = "43--52",

journal = "Neuroimage",

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T1 - Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

AU - Mullins, Paul G

AU - McGonigle, David J

AU - O'Gorman, Ruth L

AU - Puts, Nicolaas A J

AU - Vidyasagar, Rishma

AU - Evans, C John

AU - Edden, Richard A E

AU - Cardiff Symposium on MRS of GABA

PY - 2014/2/1

Y1 - 2014/2/1

N2 - There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.

AB - There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.

KW - Algorithms

KW - Brain

KW - Humans

KW - Magnetic Resonance Spectroscopy

KW - Reproducibility of Results

KW - Sensitivity and Specificity

KW - gamma-Aminobutyric Acid

KW - Journal Article

KW - Research Support, N.I.H., Extramural

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1016/j.neuroimage.2012.12.004

DO - 10.1016/j.neuroimage.2012.12.004

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SN - 1053-8119

VL - 86

SP - 43

EP - 52

JO - Neuroimage

JF - Neuroimage

ER -

Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

Crynodeb

Mynediad at Ddogfen

Ôl bys

Gweithgareddau

Editing School

Offer

Bangor Imaging UNit - 3 T MRI scanner

Dyfynnu hyn