Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma

David J. Duffy; Aleksandar Krstic; Melinda Halasz; Thomas Schwarzl; Dirk Fey; Kristiina Iljin; Jai Prakash Mehta; Kate Killick; Jenny Whilde; Benedetta Turriziani; Saija Haapa-Paananen; Vidal Fey; Matthias Fischer; Frank Westermann; Kai-Oliver Henrich; Steffen Bannert; Desmond G. Higgins; Walter Kolch

Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma

David J. Duffy
, Aleksandar Krstic
, Melinda Halasz
, Thomas Schwarzl
, Dirk Fey
, Kristiina Iljin
, Jai Prakash Mehta
, Kate Killick
, Jenny Whilde
, Benedetta Turriziani
, Saija Haapa-Paananen
, Vidal Fey
, Matthias Fischer
, Frank Westermann
, Kai-Oliver Henrich
, Steffen Bannert
, Desmond G. Higgins
, Walter Kolch

University College Dublin

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	43182-43201
Cyfnodolyn	Oncotarget
Cyfrol	6
Rhif cyhoeddi	41
Statws	Cyhoeddwyd - 22 Rhag 2015
Cyhoeddwyd yn allanol	Ie

Dyfynnu hyn

Duffy, D. J., Krstic, A., Halasz, M., Schwarzl, T., Fey, D., Iljin, K., Mehta, J. P., Killick, K., Whilde, J., Turriziani, B., Haapa-Paananen, S., Fey, V., Fischer, M., Westermann, F., Henrich, K.-O., Bannert, S., Higgins, D. G., & Kolch, W. (2015). Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma. Oncotarget, 6(41), 43182-43201.

@article{e00e4566d2284fbeb2486b272a8e694c,

title = "Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma",

keywords = "MYC (c-MYC), neuroblastoma, transcriptional regulation, mRNA sequencing (mRNA-seq), 4sU-seq",

author = "Duffy, \{David J.\} and Aleksandar Krstic and Melinda Halasz and Thomas Schwarzl and Dirk Fey and Kristiina Iljin and Mehta, \{Jai Prakash\} and Kate Killick and Jenny Whilde and Benedetta Turriziani and Saija Haapa-Paananen and Vidal Fey and Matthias Fischer and Frank Westermann and Kai-Oliver Henrich and Steffen Bannert and Higgins, \{Desmond G.\} and Walter Kolch",

year = "2015",

month = dec,

day = "22",

language = "English",

volume = "6",

pages = "43182--43201",

journal = "Oncotarget",

issn = "1949-2553",

publisher = "Impact Journals LLC",

number = "41",

}

Duffy, DJ, Krstic, A, Halasz, M, Schwarzl, T, Fey, D, Iljin, K, Mehta, JP, Killick, K, Whilde, J, Turriziani, B, Haapa-Paananen, S, Fey, V, Fischer, M, Westermann, F, Henrich, K-O, Bannert, S, Higgins, DG & Kolch, W 2015, 'Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma', Oncotarget, cyfrol. 6, rhif 41, tt. 43182-43201.

TY - JOUR

T1 - Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma

AU - Duffy, David J.

AU - Krstic, Aleksandar

AU - Halasz, Melinda

AU - Schwarzl, Thomas

AU - Fey, Dirk

AU - Iljin, Kristiina

AU - Mehta, Jai Prakash

AU - Killick, Kate

AU - Whilde, Jenny

AU - Turriziani, Benedetta

AU - Haapa-Paananen, Saija

AU - Fey, Vidal

AU - Fischer, Matthias

AU - Westermann, Frank

AU - Henrich, Kai-Oliver

AU - Bannert, Steffen

AU - Higgins, Desmond G.

AU - Kolch, Walter

PY - 2015/12/22

Y1 - 2015/12/22

KW - MYC (c-MYC)

KW - neuroblastoma

KW - transcriptional regulation

KW - mRNA sequencing (mRNA-seq)

KW - 4sU-seq

M3 - Article

SN - 1949-2553

VL - 6

SP - 43182

EP - 43201

JO - Oncotarget

JF - Oncotarget

IS - 41

ER -