Synthesis of (+)-(R)-Tiruchanduramine

Zahraa S. Al-Taie; Barbara Bartholomew; Christopher  Cartmell; Richard Froom; Russell G. Kerr; Rolf Kraehenbuehl; Paddy Murphy; Robert J. Nash; Yana B. Penkova; Alexander  van Teijlingen

doi:10.3390/molecules27041338

Synthesis of (+)-(R)-Tiruchanduramine

Zahraa S. Al-Taie
, Barbara Bartholomew
, Christopher Cartmell
, Richard Froom
, Russell G. Kerr
, Rolf Kraehenbuehl
, Paddy Murphy
, Robert J. Nash
, Yana B. Penkova
, Alexander van Teijlingen

Ysgol Gwyddorau Amgylcheddol a Naturiol

Aberystwyth University
Centre for Veterinary Epidemiological Research, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada
Bangor University
Al-Nahrain University, Baghdad

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The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.

Iaith wreiddiol	Saesneg
Cyfnodolyn	Molecules
Cyfrol	27
Rhif cyhoeddi	4
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.3390/molecules27041338
Statws	Cyhoeddwyd - 16 Chwef 2022

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10.3390/molecules27041338Trwydded: CC BY

molecules-27-01338Fersiwn derfynol wedi’i chyhoeddi, 1.71 MBTrwydded: CC BY

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title = "Synthesis of (+)-(R)-Tiruchanduramine",

abstract = "The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5\% overall yield from Fmoc-D-Dab(Boc)-OH. ",

keywords = "Synoicum macroglossum, beta-carboline, guanidines, tiruchanduramine",

author = "Al-Taie, \{Zahraa S.\} and Barbara Bartholomew and Christopher Cartmell and Richard Froom and Kerr, \{Russell G.\} and Rolf Kraehenbuehl and Paddy Murphy and Nash, \{Robert J.\} and Penkova, \{Yana B.\} and \{van Teijlingen\}, Alexander",

year = "2022",

month = feb,

day = "16",

doi = "10.3390/molecules27041338",

language = "English",

volume = "27",

journal = "Molecules",

issn = "1420-3049",

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TY - JOUR

T1 - Synthesis of (+)-(R)-Tiruchanduramine

AU - Al-Taie, Zahraa S.

AU - Bartholomew, Barbara

AU - Cartmell, Christopher

AU - Froom, Richard

AU - Kerr, Russell G.

AU - Kraehenbuehl, Rolf

AU - Murphy, Paddy

AU - Nash, Robert J.

AU - Penkova, Yana B.

AU - van Teijlingen, Alexander

PY - 2022/2/16

Y1 - 2022/2/16

N2 - The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.

AB - The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.

KW - Synoicum macroglossum

KW - beta-carboline

KW - guanidines

KW - tiruchanduramine

U2 - 10.3390/molecules27041338

DO - 10.3390/molecules27041338

M3 - Article

SN - 1420-3049

VL - 27

JO - Molecules

JF - Molecules

IS - 4

ER -

Synthesis of (+)-(R)-Tiruchanduramine

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