The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.

GD Coxon; S Knobl; E Roberts; MS Baird; JR Al Dulayymi; GS Besra; PJ Brennan; DE Minnikin

doi:10.1016/S0040-4039(99)01378-7

The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.

GD Coxon
, S Knobl
, E Roberts
, MS Baird
, JR Al Dulayymi
, GS Besra
, PJ Brennan
, DE Minnikin

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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(11R, 12S)-lactobacillic acid (1) has been prepared either from D-mannitol by asymmetric cyclopropanation or from cycyclopropane-1, 2-dimethanol by enzymatic desymmetrisation. The syntheses of (11S, 12R)-lactobacillic acid (2) and (1R, 2S) 1(3'-methoxycarbonylpropyl)-2-octadecylcopropane (26) and related analogues (27 and 28) have also been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	6689-6692
Nifer y tudalennau	4
Cyfnodolyn	Tetrahedron Letters
Cyfrol	40
Rhif cyhoeddi	36
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/S0040-4039(99)01378-7
Statws	Cyhoeddwyd - 3 Medi 1999

Mynediad at Ddogfen

10.1016/S0040-4039(99)01378-7

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@article{12c27119328a4d5b854e466959383ff8,

title = "The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.",

abstract = "(11R, 12S)-lactobacillic acid (1) has been prepared either from D-mannitol by asymmetric cyclopropanation or from cycyclopropane-1, 2-dimethanol by enzymatic desymmetrisation. The syntheses of (11S, 12R)-lactobacillic acid (2) and (1R, 2S) 1(3'-methoxycarbonylpropyl)-2-octadecylcopropane (26) and related analogues (27 and 28) have also been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.",

author = "GD Coxon and S Knobl and E Roberts and MS Baird and \{Al Dulayymi\}, JR and GS Besra and PJ Brennan and DE Minnikin",

year = "1999",

month = sep,

day = "3",

doi = "10.1016/S0040-4039(99)01378-7",

language = "English",

volume = "40",

pages = "6689--6692",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "36",

}

TY - JOUR

T1 - The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.

AU - Coxon, GD

AU - Knobl, S

AU - Roberts, E

AU - Baird, MS

AU - Al Dulayymi, JR

AU - Besra, GS

AU - Brennan, PJ

AU - Minnikin, DE

PY - 1999/9/3

Y1 - 1999/9/3

N2 - (11R, 12S)-lactobacillic acid (1) has been prepared either from D-mannitol by asymmetric cyclopropanation or from cycyclopropane-1, 2-dimethanol by enzymatic desymmetrisation. The syntheses of (11S, 12R)-lactobacillic acid (2) and (1R, 2S) 1(3'-methoxycarbonylpropyl)-2-octadecylcopropane (26) and related analogues (27 and 28) have also been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.

AB - (11R, 12S)-lactobacillic acid (1) has been prepared either from D-mannitol by asymmetric cyclopropanation or from cycyclopropane-1, 2-dimethanol by enzymatic desymmetrisation. The syntheses of (11S, 12R)-lactobacillic acid (2) and (1R, 2S) 1(3'-methoxycarbonylpropyl)-2-octadecylcopropane (26) and related analogues (27 and 28) have also been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.

U2 - 10.1016/S0040-4039(99)01378-7

DO - 10.1016/S0040-4039(99)01378-7

M3 - Article

SN - 0040-4039

VL - 40

SP - 6689

EP - 6692

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 36

ER -

The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.

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