Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

Connor  Howe; David  MacLeod; Liisa Wainman; Sam Oliver; Philip  Ainslie

doi:10.1016/j.chest.2020.04.017

Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

Connor Howe
, David MacLeod
, Liisa Wainman
, Sam Oliver
, Philip Ainslie

Duke University
University of British Columbia, Okanagan
University of British Columbia, Vancouver

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

292 Wedi eu Llwytho i Lawr (Pure)

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Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	1644-1650
Cyfnodolyn	Chest
Cyfrol	158
Rhif cyhoeddi	4
Dyddiad ar-lein cynnar	25 Ebr 2020
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/j.chest.2020.04.017
Statws	Cyhoeddwyd - 1 Hyd 2020

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10.1016/j.chest.2020.04.017

Howe_CHEST-19-3044.R1_Proof_hiLlawysgrif awdur wedi’i dderbyn, 531 KB

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title = "Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia",

abstract = "Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.",

keywords = "exercise, hypoxia, noninvasive, pulmonary gas exchange, validation",

author = "Connor Howe and David MacLeod and Liisa Wainman and Sam Oliver and Philip Ainslie",

year = "2020",

month = oct,

day = "1",

doi = "10.1016/j.chest.2020.04.017",

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T1 - Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

AU - Howe, Connor

AU - MacLeod, David

AU - Wainman, Liisa

AU - Oliver, Sam

AU - Ainslie, Philip

PY - 2020/10/1

Y1 - 2020/10/1

N2 - Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.

AB - Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.

KW - exercise

KW - hypoxia

KW - noninvasive

KW - pulmonary gas exchange

KW - validation

U2 - 10.1016/j.chest.2020.04.017

DO - 10.1016/j.chest.2020.04.017

M3 - Article

SN - 0012-3692

VL - 158

SP - 1644

EP - 1650

JO - Chest

JF - Chest

IS - 4

ER -

Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

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