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AHRQ Series on Complex Intervention Systematic Reviews - Paper 2: Defining Complexity, Formulating Scope and Questions

  • Michael P Kelly
  • , Jane Noyes
  • , Robert L Kane
  • , Christine Chang
  • , Stacey Uhl
  • , Karen A Robinson
  • , Stacey Springs
  • , Mary E Butler
  • , Jeanne-Marie Guise
    • University of Cambridge
    • University of Minnesota
    • AHRQ’s Evidence-based Practice Center, Rockville, MD
    • ECRI Institute, Plymouth Meeting, PA
    • Johns Hopkins University
    • Brown School of Public Health, Providence, RI
    • University of Oregon Health Sciences Center

    Research output: Contribution to journalArticlepeer-review

    202 Downloads (Pure)

    Abstract

    BACKGROUND: The early stages of a systematic review set the scope and expectations. This can be particularly challenging for complex interventions given their multi-dimensional and dynamic nature.

    RATIONALE: This paper builds on concepts introduced in Paper 1 of this series. It describes the methodological, practical and philosophical challenges and potential approaches for formulating the questions and scope of systematic reviews of complex interventions. Further it discusses the use of theory to help organize reviews of complex interventions.

    DISCUSSION: Many interventions in medicine, public health, education, social services, behavioral health, and community programs are complex, and they may not fit neatly within the established paradigm for reviews of straight-forward interventions. This paper provides conceptual and operational guidance for these early stages of scope formulation to assist authors of systematic reviews of complex interventions.

    Original languageEnglish
    Pages (from-to)11-18
    JournalJournal of Clinical Epidemiology
    Volume90
    Issue numberOctober
    Early online date15 Jul 2017
    DOIs
    Publication statusPublished - Oct 2017

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Complex interventions
    • Evidence-Based Medicine
    • Review Literature as Topic
    • Systematic review
    • Qualitative Research
    • Research Design

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