AHRQ Series on Complex Intervention Systematic Reviews - Paper 5: Advanced Analytic Methods

Terri Pigott; Jane Noyes; Craig A Umscheid; Evan Myers; Sally C Morton; Rongwei Fu; Gillian D Sanders-Schmidler; Emily E Beth Devine; M Hassan Murad; Michael P Kelly; Chris Fonnesbeck; Mark Petticrew; Leila Kahwati; S Natasha Beretvas

doi:10.1016/j.jclinepi.2017.06.015

AHRQ Series on Complex Intervention Systematic Reviews - Paper 5: Advanced Analytic Methods

Terri Pigott, Jane Noyes, Craig A Umscheid, Evan Myers, Sally C Morton, Rongwei Fu, Gillian D Sanders-Schmidler, Emily E Beth Devine, M Hassan Murad, Michael P Kelly, Chris Fonnesbeck, Mark Petticrew, Leila Kahwati, S Natasha Beretvas

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Abstract

BACKGROUND: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method.

RATIONALE: We present advanced analytic approaches that address four common questions that guide reviews of complex interventions: 1) How effective is the intervention?; 2) For whom does the intervention work and in what contexts?; 3) What happens when the intervention is implemented?; and 4) What decisions are possible given the results of the synthesis?

DISCUSSION: The analytic approaches presented in this paper are particularly useful when each primary study differs in components, mechanisms of action, context, implementation, timing, and many other domains.

Original language	English
Pages (from-to)	37-42
Journal	Journal of Clinical Epidemiology
Volume	90
Issue number	October
Early online date	15 Jul 2017
DOIs	https://doi.org/10.1016/j.jclinepi.2017.06.015
Publication status	Published - Oct 2017

Keywords

Systematic review
Qualitative synthesis
Meta-analysis
Decision analysis

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10.1016/j.jclinepi.2017.06.015Licence: CC BY-NC-ND

AHRQ series Paper 5Accepted author manuscript, 471 KBLicence: CC BY-NC-ND

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Pigott, T., Noyes, J., Umscheid, C. A., Myers, E., Morton, S. C., Fu, R., Sanders-Schmidler, G. D., Devine, E. E. B., Murad, M. H., Kelly, M. P., Fonnesbeck, C., Petticrew, M., Kahwati, L., & Beretvas, S. N. (2017). AHRQ Series on Complex Intervention Systematic Reviews - Paper 5: Advanced Analytic Methods. Journal of Clinical Epidemiology, 90(October), 37-42. https://doi.org/10.1016/j.jclinepi.2017.06.015

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title = "AHRQ Series on Complex Intervention Systematic Reviews - Paper 5: Advanced Analytic Methods",

abstract = "BACKGROUND: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method.RATIONALE: We present advanced analytic approaches that address four common questions that guide reviews of complex interventions: 1) How effective is the intervention?; 2) For whom does the intervention work and in what contexts?; 3) What happens when the intervention is implemented?; and 4) What decisions are possible given the results of the synthesis?DISCUSSION: The analytic approaches presented in this paper are particularly useful when each primary study differs in components, mechanisms of action, context, implementation, timing, and many other domains.",

keywords = "Systematic review, Qualitative synthesis, Meta-analysis, Decision analysis",

author = "Terri Pigott and Jane Noyes and Umscheid, {Craig A} and Evan Myers and Morton, {Sally C} and Rongwei Fu and Sanders-Schmidler, {Gillian D} and Devine, {Emily E Beth} and Murad, {M Hassan} and Kelly, {Michael P} and Chris Fonnesbeck and Mark Petticrew and Leila Kahwati and Beretvas, {S Natasha}",

note = "This work was funded by the following contracts HHSA290201200004C",

year = "2017",

month = oct,

doi = "10.1016/j.jclinepi.2017.06.015",

language = "English",

volume = "90",

pages = "37--42",

journal = "Journal of Clinical Epidemiology",

issn = "0895-4356",

publisher = "Elsevier",

number = "October",

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Pigott, T, Noyes, J, Umscheid, CA, Myers, E, Morton, SC, Fu, R, Sanders-Schmidler, GD, Devine, EEB, Murad, MH, Kelly, MP, Fonnesbeck, C, Petticrew, M, Kahwati, L & Beretvas, SN 2017, 'AHRQ Series on Complex Intervention Systematic Reviews - Paper 5: Advanced Analytic Methods', Journal of Clinical Epidemiology, vol. 90, no. October, pp. 37-42. https://doi.org/10.1016/j.jclinepi.2017.06.015

TY - JOUR

T1 - AHRQ Series on Complex Intervention Systematic Reviews - Paper 5

T2 - Advanced Analytic Methods

AU - Pigott, Terri

AU - Noyes, Jane

AU - Umscheid, Craig A

AU - Myers, Evan

AU - Morton, Sally C

AU - Fu, Rongwei

AU - Sanders-Schmidler, Gillian D

AU - Devine, Emily E Beth

AU - Murad, M Hassan

AU - Kelly, Michael P

AU - Fonnesbeck, Chris

AU - Petticrew, Mark

AU - Kahwati, Leila

AU - Beretvas, S Natasha

N1 - This work was funded by the following contracts HHSA290201200004C

PY - 2017/10

Y1 - 2017/10

N2 - BACKGROUND: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method.RATIONALE: We present advanced analytic approaches that address four common questions that guide reviews of complex interventions: 1) How effective is the intervention?; 2) For whom does the intervention work and in what contexts?; 3) What happens when the intervention is implemented?; and 4) What decisions are possible given the results of the synthesis?DISCUSSION: The analytic approaches presented in this paper are particularly useful when each primary study differs in components, mechanisms of action, context, implementation, timing, and many other domains.

AB - BACKGROUND: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method.RATIONALE: We present advanced analytic approaches that address four common questions that guide reviews of complex interventions: 1) How effective is the intervention?; 2) For whom does the intervention work and in what contexts?; 3) What happens when the intervention is implemented?; and 4) What decisions are possible given the results of the synthesis?DISCUSSION: The analytic approaches presented in this paper are particularly useful when each primary study differs in components, mechanisms of action, context, implementation, timing, and many other domains.

KW - Systematic review

KW - Qualitative synthesis

KW - Meta-analysis

KW - Decision analysis

U2 - 10.1016/j.jclinepi.2017.06.015

DO - 10.1016/j.jclinepi.2017.06.015

M3 - Article

C2 - 28720512

SN - 0895-4356

VL - 90

SP - 37

EP - 42

JO - Journal of Clinical Epidemiology

JF - Journal of Clinical Epidemiology

IS - October

ER -

AHRQ Series on Complex Intervention Systematic Reviews - Paper 5: Advanced Analytic Methods

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