Arabino mycolates from synthetic mycolic acids

Moshin O. Mohammed, Mark Baird, Juma'a Al-Dulayymi, Alison Jones, Christopher Gwenin

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    Abstract

    The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.
    Original languageEnglish
    Pages (from-to)2849-2857
    JournalTetrahedron
    Volume72
    Issue number22
    Early online date31 Mar 2016
    DOIs
    Publication statusPublished - 2 Jun 2016

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