Arabino mycolates from synthetic mycolic acids

Moshin O.  Mohammed; Mark Baird; Juma'a Al-Dulayymi; Alison Jones; Christopher Gwenin

doi:10.1016/j.tet.2016.03.083

Arabino mycolates from synthetic mycolic acids

Moshin O. Mohammed, Mark Baird, Juma'a Al-Dulayymi, Alison Jones, Christopher Gwenin

Kirkuk University

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Abstract

The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.

Original language	English
Pages (from-to)	2849-2857
Journal	Tetrahedron
Volume	72
Issue number	22
Early online date	31 Mar 2016
DOIs	https://doi.org/10.1016/j.tet.2016.03.083
Publication status	Published - 2 Jun 2016

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2016 Arabino Mycolates from synthetic mycolic acidsAccepted author manuscript, 1.73 MB

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title = "Arabino mycolates from synthetic mycolic acids",

abstract = "The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.",

author = "Mohammed, \{Moshin O.\} and Mark Baird and Juma'a Al-Dulayymi and Alison Jones and Christopher Gwenin",

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AU - Mohammed, Moshin O.

AU - Baird, Mark

AU - Al-Dulayymi, Juma'a

AU - Jones, Alison

AU - Gwenin, Christopher

N1 - Ministry of Higher Education & Scientific Research–Kurdistan Region, Iraq

PY - 2016/6/2

Y1 - 2016/6/2

N2 - The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.

AB - The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.

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DO - 10.1016/j.tet.2016.03.083

M3 - Article

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VL - 72

SP - 2849

EP - 2857

JO - Tetrahedron

JF - Tetrahedron

IS - 22

ER -

Arabino mycolates from synthetic mycolic acids

Abstract

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