Broadband microchamber for electrical detection of live and dead biological cells

C. Palego; C. Merla; Y. Ning; C. Multari; X. Cheng; D. Molinario; G. Ding; X. Luo; J. Hwang

doi:10.1109/MWSYM.2013.6697355

Broadband microchamber for electrical detection of live and dead biological cells

C. Palego, C. Merla, Y. Ning, C. Multari, X. Cheng, D. Molinario, G. Ding, X. Luo, J. Hwang

Research output: Contribution to conference › Paper

Abstract

A novel broadband microchamber for electrical detection of live and dead biological cells was designed, fabricated and tested. The microchamber was formed between a gold coplanar waveguide fabricated on a quartz slide and the microfluidic channels fabricated in a polydimethylsiloxane cover. The coplanar waveguide allowed broadband impedance matching and efficient cell trapping. The microfluidic channels delivered single cells precisely. Tests on Jurkat cells in both time and frequency domains showed that live cells had lower resistance but higher capacitance than that of dead cells

Original language	English
DOIs	https://doi.org/10.1109/MWSYM.2013.6697355
Publication status	Published - 2 Jun 2013
Event	IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013 - Duration: 3 Jan 0001 → …

Conference

Conference	IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013
Period	3/01/01 → …

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10.1109/MWSYM.2013.6697355

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abstract = "A novel broadband microchamber for electrical detection of live and dead biological cells was designed, fabricated and tested. The microchamber was formed between a gold coplanar waveguide fabricated on a quartz slide and the microfluidic channels fabricated in a polydimethylsiloxane cover. The coplanar waveguide allowed broadband impedance matching and efficient cell trapping. The microfluidic channels delivered single cells precisely. Tests on Jurkat cells in both time and frequency domains showed that live cells had lower resistance but higher capacitance than that of dead cells",

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AU - Palego, C.

AU - Merla, C.

AU - Ning, Y.

AU - Multari, C.

AU - Cheng, X.

AU - Molinario, D.

AU - Ding, G.

AU - Luo, X.

AU - Hwang, J.

PY - 2013/6/2

Y1 - 2013/6/2

N2 - A novel broadband microchamber for electrical detection of live and dead biological cells was designed, fabricated and tested. The microchamber was formed between a gold coplanar waveguide fabricated on a quartz slide and the microfluidic channels fabricated in a polydimethylsiloxane cover. The coplanar waveguide allowed broadband impedance matching and efficient cell trapping. The microfluidic channels delivered single cells precisely. Tests on Jurkat cells in both time and frequency domains showed that live cells had lower resistance but higher capacitance than that of dead cells

AB - A novel broadband microchamber for electrical detection of live and dead biological cells was designed, fabricated and tested. The microchamber was formed between a gold coplanar waveguide fabricated on a quartz slide and the microfluidic channels fabricated in a polydimethylsiloxane cover. The coplanar waveguide allowed broadband impedance matching and efficient cell trapping. The microfluidic channels delivered single cells precisely. Tests on Jurkat cells in both time and frequency domains showed that live cells had lower resistance but higher capacitance than that of dead cells

U2 - 10.1109/MWSYM.2013.6697355

DO - 10.1109/MWSYM.2013.6697355

M3 - Paper

T2 - IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013

Y2 - 3 January 0001

ER -

Broadband microchamber for electrical detection of live and dead biological cells

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