Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid

Chester Blackburn; Hongyun Tai; Martina Salerno; Xi Wang; Chandra Senan; Ian Ratcliffe; Edgar Hartsuiker; Wenxin Wang

doi:10.1016/j.dib.2019.104861

Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid

Chester Blackburn
, Hongyun Tai
, Martina Salerno
, Xi Wang
, Chandra Senan
, Ian Ratcliffe
, Edgar Hartsuiker
, Wenxin Wang

Glyndwr University
University College Dublin

Research output: Contribution to journal › Article › peer-review

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Abstract

The data presented in this manuscript presents the characterisation spectra of three hyperbranched polymers as discussed in the paper “Folic Acid and Rhodamine Labelled pH Responsive Hyperbranched Polymers: synthesis, characterization and cell uptake studies”[1]. Characterisation of polymers was performed via 1H Nuclear Magnetic Resonance (1H NMR) and Size Exclusion Chromatography (SEC). pH responsive characteristics were observed via Dynamic Light Scattering (DLS). The data for characterisation of folate conjugated hyperbranched polymer is presented as 1H NMR, Ultra Violet Visible (UV-VIS) spectra and DLS measurements. Further data is presented detailing the experiments for the synthesis of monomers 2-propyl acrylic acid (PAA) and disulfide diacrylate (DSDA), with the full synthesis of folic acidpoly(ethylene glycol) (PEG) linker, rhodamine B ethylenediamine linker and bioconjugation reactions also detailed.

Original language	English
Article number	104861
Journal	Data in Brief
Volume	28
Early online date	21 Nov 2019
DOIs	https://doi.org/10.1016/j.dib.2019.104861
Publication status	Published - Feb 2020

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2020 Data presentingFinal published version, 1.84 MBLicence: CC BY

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title = "Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid",

abstract = "The data presented in this manuscript presents the characterisation spectra of three hyperbranched polymers as discussed in the paper “Folic Acid and Rhodamine Labelled pH Responsive Hyperbranched Polymers: synthesis, characterization and cell uptake studies”[1]. Characterisation of polymers was performed via 1H Nuclear Magnetic Resonance (1H NMR) and Size Exclusion Chromatography (SEC). pH responsive characteristics were observed via Dynamic Light Scattering (DLS). The data for characterisation of folate conjugated hyperbranched polymer is presented as 1H NMR, Ultra Violet Visible (UV-VIS) spectra and DLS measurements. Further data is presented detailing the experiments for the synthesis of monomers 2-propyl acrylic acid (PAA) and disulfide diacrylate (DSDA), with the full synthesis of folic acidpoly(ethylene glycol) (PEG) linker, rhodamine B ethylenediamine linker and bioconjugation reactions also detailed. ",

author = "Chester Blackburn and Hongyun Tai and Martina Salerno and Xi Wang and Chandra Senan and Ian Ratcliffe and Edgar Hartsuiker and Wenxin Wang",

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doi = "10.1016/j.dib.2019.104861",

language = "English",

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T1 - Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid

AU - Blackburn, Chester

AU - Tai, Hongyun

AU - Salerno, Martina

AU - Wang, Xi

AU - Senan, Chandra

AU - Ratcliffe, Ian

AU - Hartsuiker, Edgar

AU - Wang, Wenxin

PY - 2020/2

Y1 - 2020/2

N2 - The data presented in this manuscript presents the characterisation spectra of three hyperbranched polymers as discussed in the paper “Folic Acid and Rhodamine Labelled pH Responsive Hyperbranched Polymers: synthesis, characterization and cell uptake studies”[1]. Characterisation of polymers was performed via 1H Nuclear Magnetic Resonance (1H NMR) and Size Exclusion Chromatography (SEC). pH responsive characteristics were observed via Dynamic Light Scattering (DLS). The data for characterisation of folate conjugated hyperbranched polymer is presented as 1H NMR, Ultra Violet Visible (UV-VIS) spectra and DLS measurements. Further data is presented detailing the experiments for the synthesis of monomers 2-propyl acrylic acid (PAA) and disulfide diacrylate (DSDA), with the full synthesis of folic acidpoly(ethylene glycol) (PEG) linker, rhodamine B ethylenediamine linker and bioconjugation reactions also detailed.

AB - The data presented in this manuscript presents the characterisation spectra of three hyperbranched polymers as discussed in the paper “Folic Acid and Rhodamine Labelled pH Responsive Hyperbranched Polymers: synthesis, characterization and cell uptake studies”[1]. Characterisation of polymers was performed via 1H Nuclear Magnetic Resonance (1H NMR) and Size Exclusion Chromatography (SEC). pH responsive characteristics were observed via Dynamic Light Scattering (DLS). The data for characterisation of folate conjugated hyperbranched polymer is presented as 1H NMR, Ultra Violet Visible (UV-VIS) spectra and DLS measurements. Further data is presented detailing the experiments for the synthesis of monomers 2-propyl acrylic acid (PAA) and disulfide diacrylate (DSDA), with the full synthesis of folic acidpoly(ethylene glycol) (PEG) linker, rhodamine B ethylenediamine linker and bioconjugation reactions also detailed.

U2 - 10.1016/j.dib.2019.104861

DO - 10.1016/j.dib.2019.104861

M3 - Article

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SN - 2352-3409

VL - 28

JO - Data in Brief

JF - Data in Brief

M1 - 104861

ER -

Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid

Abstract

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