Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex

K. Oscarsson; M. Lahmann; J. Lindberg; J. Kangasmetsa; T. Unge; S. Oscarson; A. Hallberg; B. Samuelsson

doi:10.1016/S0968-0896(02)00535-7

Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex

K. Oscarsson, M. Lahmann, J. Lindberg, J. Kangasmetsa, T. Unge, S. Oscarson, A. Hallberg, B. Samuelsson

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1107-1115
Journal	Bioorganic and Medicinal Chemistry
Volume	11
Issue number	6
DOIs	https://doi.org/10.1016/S0968-0896(02)00535-7
Publication status	Published - 20 Mar 2003

Keywords

BIOCHEMISTRY & MOLECULAR BIOLOGY
CHEMISTRY
MEDICINAL
ORGANIC

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0968-0896(02)00535-7

Cite this

Oscarsson, K., Lahmann, M., Lindberg, J., Kangasmetsa, J., Unge, T., Oscarson, S., Hallberg, A., & Samuelsson, B. (2003). Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex. Bioorganic and Medicinal Chemistry, 11(6), 1107-1115. https://doi.org/10.1016/S0968-0896(02)00535-7

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keywords = "BIOCHEMISTRY \& MOLECULAR BIOLOGY, CHEMISTRY, MEDICINAL, ORGANIC",

author = "K. Oscarsson and M. Lahmann and J. Lindberg and J. Kangasmetsa and T. Unge and S. Oscarson and A. Hallberg and B. Samuelsson",

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Oscarsson, K, Lahmann, M, Lindberg, J, Kangasmetsa, J, Unge, T, Oscarson, S, Hallberg, A & Samuelsson, B 2003, 'Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex', Bioorganic and Medicinal Chemistry, vol. 11, no. 6, pp. 1107-1115. https://doi.org/10.1016/S0968-0896(02)00535-7

Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex. / Oscarsson, K.; Lahmann, M.; Lindberg, J. et al.
In: Bioorganic and Medicinal Chemistry, Vol. 11, No. 6, 20.03.2003, p. 1107-1115.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex

AU - Oscarsson, K.

AU - Lahmann, M.

AU - Lindberg, J.

AU - Kangasmetsa, J.

AU - Unge, T.

AU - Oscarson, S.

AU - Hallberg, A.

AU - Samuelsson, B.

PY - 2003/3/20

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KW - CHEMISTRY

KW - MEDICINAL

KW - ORGANIC

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DO - 10.1016/S0968-0896(02)00535-7

M3 - Article

SN - 0968-0896

VL - 11

SP - 1107

EP - 1115

JO - Bioorganic and Medicinal Chemistry

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Oscarsson K, Lahmann M, Lindberg J, Kangasmetsa J, Unge T, Oscarson S et al. Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex. Bioorganic and Medicinal Chemistry. 2003 Mar 20;11(6):1107-1115. doi: 10.1016/S0968-0896(02)00535-7