Impaired visuospatial transformation but intact sequence processing in Parkinson disease

C. Leek; E.C. Leek; J.H. Kerai; S.J. Johnston; J.V. Hindle; R.M. Bracewell

doi:10.1097/WNN.0000000000000032

Impaired visuospatial transformation but intact sequence processing in Parkinson disease

C. Leek, E.C. Leek, J.H. Kerai, S.J. Johnston, J.V. Hindle, R.M. Bracewell

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Abstract

We examined whether visuospatial deficits in Parkinson disease (PD) can be explained by a domain-general, The authors examined whether visuospatial deficits in Parkinson's disease (PD) can be explained by a domain–general, nonspatial impairment in the sequencing or serial chaining of mental operations. They argue that visuospatial deficits in PD result from impairments to spatial transformation routines involved in the computation of mappings between spatial locations. These routines are mediated by dopaminergic pathways linking the basal ganglia, prefrontal cortex, supplementary motor area, and parietal cortex.

Original language	English
Pages (from-to)	130-138
Journal	Cognitive and Behavioral Neurology
Volume	27
Issue number	3
DOIs	https://doi.org/10.1097/WNN.0000000000000032
Publication status	Published - 1 Sept 2014

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AU - Bracewell, R.M.

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Impaired visuospatial transformation but intact sequence processing in Parkinson disease

Abstract

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