Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

Z.A. Al-Shuhaib, E. Doerksen, J.M. Page, Z. Al-Shuhaiba, H. Böckemeier, L. Coghlan, E. Dörksena, I.V. Jones, P.J. Murphy, R.P. Nash

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    Abstract

    The Pd-mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.
    Original languageEnglish
    Pages (from-to)6716-6718
    JournalTetrahedron Letters
    Volume54
    Issue number49
    DOIs
    Publication statusPublished - 27 Sept 2013

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    • Intramolecular epoxide ring opening cyclisation reactions involving guanidines

      Al-Shuhaib, Z., Arndt, M., Dennis, M., Evans, D., Jones, I., Leitmann, V., Murphy, P., Roberts, D., Rowles, R., Sadaghiani, Y. K., Thornhill, A. J., Nash, R. J., Hollinshead, J., Bartholomew, B., Tizzard, G. & Coles, S., 16 Feb 2017, In: Tetrahedron. 73, 7, p. 845-852 8 p.

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