Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

Z.A. Al-Shuhaib; E. Doerksen; J.M. Page; Z. Al-Shuhaiba; H. Böckemeier; L. Coghlan; E. Dörksena; I.V. Jones; P.J. Murphy; R.P. Nash

doi:10.1016/j.tetlet.2013.09.093

Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

Z.A. Al-Shuhaib, E. Doerksen, J.M. Page, Z. Al-Shuhaiba, H. Böckemeier, L. Coghlan, E. Dörksena, I.V. Jones, P.J. Murphy, R.P. Nash

Research output: Contribution to journal › Article › peer-review

Abstract

The Pd-mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.

Original language	English
Pages (from-to)	6716-6718
Journal	Tetrahedron Letters
Volume	54
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2013.09.093
Publication status	Published - 27 Sept 2013

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10.1016/j.tetlet.2013.09.093

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title = "Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines",

abstract = "The Pd-mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.",

author = "Z.A. Al-Shuhaib and E. Doerksen and J.M. Page and Z. Al-Shuhaiba and H. B{\"o}ckemeier and L. Coghlan and E. D{\"o}rksena and I.V. Jones and P.J. Murphy and R.P. Nash",

year = "2013",

month = sep,

day = "27",

doi = "10.1016/j.tetlet.2013.09.093",

language = "English",

volume = "54",

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journal = "Tetrahedron Letters",

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T1 - Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

AU - Al-Shuhaib, Z.A.

AU - Doerksen, E.

AU - Page, J.M.

AU - Al-Shuhaiba, Z.

AU - Böckemeier, H.

AU - Coghlan, L.

AU - Dörksena, E.

AU - Jones, I.V.

AU - Murphy, P.J.

AU - Nash, R.P.

PY - 2013/9/27

Y1 - 2013/9/27

N2 - The Pd-mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.

AB - The Pd-mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.

UR - http://0-www.sciencedirect.com.unicat.bangor.ac.uk/science/article/pii/S0040403913016584

U2 - 10.1016/j.tetlet.2013.09.093

DO - 10.1016/j.tetlet.2013.09.093

M3 - Article

SN - 0040-4039

VL - 54

SP - 6716

EP - 6718

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

Abstract

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Intramolecular epoxide ring opening cyclisation reactions involving guanidines

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