Retinoic acid and TGF-beta signalling cooperate to overcome MYCN-induced retinoid resistance

David J. Duffy; Aleksandar Krstic; Melinda Halasz; Thomas Schwarzl; Anja Konietzny; Kristiina Iljin; Desmond G. Higgins; Walter Kolch

doi:10.1186/s13073-017-0407-3

Retinoic acid and TGF-beta signalling cooperate to overcome MYCN-induced retinoid resistance

David J. Duffy
, Aleksandar Krstic
, Melinda Halasz
, Thomas Schwarzl
, Anja Konietzny
, Kristiina Iljin
, Desmond G. Higgins
, Walter Kolch

University College Dublin

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Genome Medicine
Volume	9
DOIs	https://doi.org/10.1186/s13073-017-0407-3
Publication status	Published - 10 Feb 2017
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Neuroblastoma
Kartogenin (KGN)
RepSox
MYC (c-MYC)
Differentiation
mRNA sequencing (mRNA-seq)
ChIP sequencing (ChIP-seq)
Transforming growth factor beta (TGF-beta) signalling
Interaction proteomics
Precision medicine
Genome medicine
Wnt beta-catenin signalling
Cancer
Systems medicine
Neuronal differentiation
Differentiation therapy

Access to Document

10.1186/s13073-017-0407-3

Cite this

@article{08a147896129470db2652f0e7ff8d9d9,

title = "Retinoic acid and TGF-beta signalling cooperate to overcome MYCN-induced retinoid resistance",

keywords = "Neuroblastoma, Kartogenin (KGN), RepSox, MYC (c-MYC), Differentiation, mRNA sequencing (mRNA-seq), ChIP sequencing (ChIP-seq), Transforming growth factor beta (TGF-beta) signalling, Interaction proteomics, Precision medicine, Genome medicine, Wnt beta-catenin signalling, Cancer, Systems medicine, Neuronal differentiation, Differentiation therapy",

author = "Duffy, \{David J.\} and Aleksandar Krstic and Melinda Halasz and Thomas Schwarzl and Anja Konietzny and Kristiina Iljin and Higgins, \{Desmond G.\} and Walter Kolch",

year = "2017",

month = feb,

day = "10",

doi = "10.1186/s13073-017-0407-3",

language = "English",

volume = "9",

journal = "Genome Medicine",

issn = "1756-994X",

publisher = "BioMed Central",

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TY - JOUR

T1 - Retinoic acid and TGF-beta signalling cooperate to overcome MYCN-induced retinoid resistance

AU - Duffy, David J.

AU - Krstic, Aleksandar

AU - Halasz, Melinda

AU - Schwarzl, Thomas

AU - Konietzny, Anja

AU - Iljin, Kristiina

AU - Higgins, Desmond G.

AU - Kolch, Walter

PY - 2017/2/10

Y1 - 2017/2/10

KW - Neuroblastoma

KW - Kartogenin (KGN)

KW - RepSox

KW - MYC (c-MYC)

KW - Differentiation

KW - mRNA sequencing (mRNA-seq)

KW - ChIP sequencing (ChIP-seq)

KW - Transforming growth factor beta (TGF-beta) signalling

KW - Interaction proteomics

KW - Precision medicine

KW - Genome medicine

KW - Wnt beta-catenin signalling

KW - Cancer

KW - Systems medicine

KW - Neuronal differentiation

KW - Differentiation therapy

U2 - 10.1186/s13073-017-0407-3

DO - 10.1186/s13073-017-0407-3

M3 - Article

SN - 1756-994X

VL - 9

JO - Genome Medicine

JF - Genome Medicine

ER -