Single Cell Microdosimetric Studies Comparing Ideal and Measured Nanosecond Pulsed Electric Fields

A. Denzi; C. Merla; C. Palego; F. Apollonio; J.C. Hwang; M. Liberti

doi:10.1109/MWSYM.2013.6697655

Single Cell Microdosimetric Studies Comparing Ideal and Measured Nanosecond Pulsed Electric Fields

A. Denzi, C. Merla, C. Palego, F. Apollonio, J.C. Hwang, M. Liberti

Research output: Contribution to conference › Paper

Abstract

Recently, the promising effects induced by pulsed electric fields with high intensity and short duration have been highlighted. At the nanosecond time scale, electric pulse targets become both the plasmatic membrane and the sub-cellular structures (possibility of intracellular manipulation). In this paper, a circuit cell model with nucleus is presented, validated and used in order to assess the different cellular and sub-cellular (i.e. nucleus) effects, comparing ideal nanosecond pulsed electric fields (nsPEFs) waveforms with the ones measured from a planar, broadband matched microchamber.

Original language	English
DOIs	https://doi.org/10.1109/MWSYM.2013.6697655
Publication status	Published - 2 Jun 2013
Event	IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013 - Duration: 3 Jan 0001 → …

Conference

Conference	IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013
Period	3/01/01 → …

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10.1109/MWSYM.2013.6697655

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abstract = "Recently, the promising effects induced by pulsed electric fields with high intensity and short duration have been highlighted. At the nanosecond time scale, electric pulse targets become both the plasmatic membrane and the sub-cellular structures (possibility of intracellular manipulation). In this paper, a circuit cell model with nucleus is presented, validated and used in order to assess the different cellular and sub-cellular (i.e. nucleus) effects, comparing ideal nanosecond pulsed electric fields (nsPEFs) waveforms with the ones measured from a planar, broadband matched microchamber.",

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AU - Denzi, A.

AU - Merla, C.

AU - Palego, C.

AU - Apollonio, F.

AU - Hwang, J.C.

AU - Liberti, M.

PY - 2013/6/2

Y1 - 2013/6/2

N2 - Recently, the promising effects induced by pulsed electric fields with high intensity and short duration have been highlighted. At the nanosecond time scale, electric pulse targets become both the plasmatic membrane and the sub-cellular structures (possibility of intracellular manipulation). In this paper, a circuit cell model with nucleus is presented, validated and used in order to assess the different cellular and sub-cellular (i.e. nucleus) effects, comparing ideal nanosecond pulsed electric fields (nsPEFs) waveforms with the ones measured from a planar, broadband matched microchamber.

AB - Recently, the promising effects induced by pulsed electric fields with high intensity and short duration have been highlighted. At the nanosecond time scale, electric pulse targets become both the plasmatic membrane and the sub-cellular structures (possibility of intracellular manipulation). In this paper, a circuit cell model with nucleus is presented, validated and used in order to assess the different cellular and sub-cellular (i.e. nucleus) effects, comparing ideal nanosecond pulsed electric fields (nsPEFs) waveforms with the ones measured from a planar, broadband matched microchamber.

U2 - 10.1109/MWSYM.2013.6697655

DO - 10.1109/MWSYM.2013.6697655

M3 - Paper

T2 - IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013

Y2 - 3 January 0001

ER -

Single Cell Microdosimetric Studies Comparing Ideal and Measured Nanosecond Pulsed Electric Fields

Abstract

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