Synthetic trehalose di- and mono-esters of alpha-, methoxy- and keto-mycolic acids

J.R. Al-Dulayymi; M.S. Baird; M. Maza-Iglesias; R.T. Hameed; K.S. Baols; M. Muzael; A.D. Saleh

doi:10.1016/j.tet.2014.10.072

Synthetic trehalose di- and mono-esters of alpha-, methoxy- and keto-mycolic acids

J.R. Al-Dulayymi, M.S. Baird, M. Maza-Iglesias, R.T. Hameed, K.S. Baols, M. Muzael, A.D. Saleh

Research output: Contribution to journal › Article › peer-review

Abstract

Synthetic mycolic acids matching the overall structure of the major mycolic acids of Mycobacterium tuberculosis are coupled to trehalose to generate the corresponding synthetic trehalose monomycolate (TMM) and trehalose dimycolate (TDM; cord factor), either with two identical or two different mycolic acids.

Original language	English
Pages (from-to)	9836–9852
Journal	Tetrahedron
Volume	70
Issue number	52
Early online date	1 Nov 2014
DOIs	https://doi.org/10.1016/j.tet.2014.10.072
Publication status	Published - 30 Dec 2014

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10.1016/j.tet.2014.10.072

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title = "Synthetic trehalose di- and mono-esters of alpha-, methoxy- and keto-mycolic acids",

abstract = "Synthetic mycolic acids matching the overall structure of the major mycolic acids of Mycobacterium tuberculosis are coupled to trehalose to generate the corresponding synthetic trehalose monomycolate (TMM) and trehalose dimycolate (TDM; cord factor), either with two identical or two different mycolic acids.",

author = "J.R. Al-Dulayymi and M.S. Baird and M. Maza-Iglesias and R.T. Hameed and K.S. Baols and M. Muzael and A.D. Saleh",

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T1 - Synthetic trehalose di- and mono-esters of alpha-, methoxy- and keto-mycolic acids

AU - Al-Dulayymi, J.R.

AU - Baird, M.S.

AU - Maza-Iglesias, M.

AU - Hameed, R.T.

AU - Baols, K.S.

AU - Muzael, M.

AU - Saleh, A.D.

PY - 2014/12/30

Y1 - 2014/12/30

N2 - Synthetic mycolic acids matching the overall structure of the major mycolic acids of Mycobacterium tuberculosis are coupled to trehalose to generate the corresponding synthetic trehalose monomycolate (TMM) and trehalose dimycolate (TDM; cord factor), either with two identical or two different mycolic acids.

AB - Synthetic mycolic acids matching the overall structure of the major mycolic acids of Mycobacterium tuberculosis are coupled to trehalose to generate the corresponding synthetic trehalose monomycolate (TMM) and trehalose dimycolate (TDM; cord factor), either with two identical or two different mycolic acids.

U2 - 10.1016/j.tet.2014.10.072

DO - 10.1016/j.tet.2014.10.072

M3 - Article

SN - 0040-4020

VL - 70

SP - 9836

EP - 9852

JO - Tetrahedron

JF - Tetrahedron

IS - 52

ER -

Synthetic trehalose di- and mono-esters of alpha-, methoxy- and keto-mycolic acids

Abstract

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