The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture

  • Piet Geusens
  • , J. van den Bergh
  • , C. Roux
  • , R. Chapurlat
  • , J. Center
  • , Dana Bliuc
  • , C. Wyers
  • , M K Javaid
  • , N. Li
  • , D. Whittier
  • , W. F. Lems

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose of Review
We review the literature about patients 50 years and older with a recent clinical fracture for the presence of skeletal and extra-skeletal risks, their perspectives of imminent subsequent fracture, falls, mortality, and other risks, and on the role of the fracture liaison service (FLS) for timely secondary fracture prevention.

Recent Findings
Patients with a recent clinical fracture present with heterogeneous patterns of bone-, fall-, and comorbidity-related risks. Short-term perspectives include bone loss, increased risk of fractures, falls, and mortality, and a decrease in physical performance and quality of life. Combined evaluation of bone, fall risk, and the presence of associated comorbidities contributes to treatment strategies.

Summary
Since fractures are related to interactions of bone-, fall-, and comorbidity-related risks, there is no one-single-discipline-fits-all approach but a need for a multidisciplinary approach at the FLS to consider all phenotypes for evaluation and treatment in an individual patient.
Original languageEnglish
Pages (from-to)611-620
JournalCurrent Osteoporosis Reports
Volume22
DOIs
Publication statusPublished - 10 Sept 2024

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