The Synthesis of Single Enantiomers of α-Mycolic Acids of Mycobacterium tuberculosis and Related Organisms, with Alternative Cyclopropane Stereochemistries

Chioma Don Lawson; Max Maza-Iglesias; Mark Baird; Muthana Sirhan; Juma'a Al-Dulayymi

doi:10.1055/s-0036-1588556; Art ID: so-2017-d0021-op

The Synthesis of Single Enantiomers of α-Mycolic Acids of Mycobacterium tuberculosis and Related Organisms, with Alternative Cyclopropane Stereochemistries

Chioma Don Lawson, Max Maza-Iglesias, Mark Baird, Muthana Sirhan, Juma'a Al-Dulayymi

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Abstract

We report the synthesis of three stereoisomers of a mycolic
acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane
and of two stereoisomers of a mycolic acid containing a proximal transcyclopropane
and a distal cis-cyclopropane

Original language	English
Journal	SynOpen
DOIs	https://doi.org/10.1055/s-0036-1588556; Art ID: so-2017-d0021-op
Publication status	Published - 31 May 2017

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10.1055/s-0036-1588556; Art ID: so-2017-d0021-op

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title = "The Synthesis of Single Enantiomers of α-Mycolic Acids of Mycobacterium tuberculosis and Related Organisms, with Alternative Cyclopropane Stereochemistries",

abstract = "We report the synthesis of three stereoisomers of a mycolic acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane and of two stereoisomers of a mycolic acid containing a proximal transcyclopropane and a distal cis-cyclopropane",

author = "\{Don Lawson\}, Chioma and Max Maza-Iglesias and Mark Baird and Muthana Sirhan and Juma'a Al-Dulayymi",

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AU - Don Lawson, Chioma

AU - Maza-Iglesias, Max

AU - Baird, Mark

AU - Sirhan, Muthana

AU - Al-Dulayymi, Juma'a

PY - 2017/5/31

Y1 - 2017/5/31

N2 - We report the synthesis of three stereoisomers of a mycolic acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane and of two stereoisomers of a mycolic acid containing a proximal transcyclopropane and a distal cis-cyclopropane

AB - We report the synthesis of three stereoisomers of a mycolic acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane and of two stereoisomers of a mycolic acid containing a proximal transcyclopropane and a distal cis-cyclopropane

U2 - 10.1055/s-0036-1588556; Art ID: so-2017-d0021-op

DO - 10.1055/s-0036-1588556; Art ID: so-2017-d0021-op

M3 - Article

SN - 2509-9396

JO - SynOpen

JF - SynOpen

ER -

The Synthesis of Single Enantiomers of α-Mycolic Acids of Mycobacterium tuberculosis and Related Organisms, with Alternative Cyclopropane Stereochemistries

Abstract

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