TY - JOUR
T1 - Trends in organ donation in England, Scotland and Wales in the context of the COVID-19 pandemic and ‘opt-out' legislation
AU - O'Neill, Stephen
AU - Thomas, Karen
AU - McLaughlin, Leah
AU - Boadu, Paul
AU - Williams, Lorraine
AU - Al-Haboubi1, Mustafa
AU - Bostock, Jennifer
AU - Noyes, Jane
AU - Mays, Nicholas
N1 - Copyright: © 2024 O'Neill et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2024/7/31
Y1 - 2024/7/31
N2 - Background:
In May 2020, England implemented soft ‘opt-out’ or ‘deemed consent’ for deceased donation with the intention of raising consent rates. However, this coincided with the COVID-19 pandemic, making it difficult to assess the early impact of the law change. Wales and Scotland changed their organ donation legislation to implement soft opt-out systems in 2015 and 2021 respectively. This study provides a descriptive analysis of changes in consent and transplant rates for deceased organ donation in England, Scotland and Wales.
Methods:
Logistic regression and descriptive trend analysis were employed to assess the probability of a patient who died in critical care becoming a donor, and to report consent rates using data, respectively, from the Intensive Care National Audit and Research Centre (ICNARC) in England from 1 April 2014 to 30 September 2021, and from the Potential Donor Audit for England, Scotland and Wales from April 2010 to June 2023.
Results:
The number of eligible donors in April-June 2020 were 56.5%, 59.3% and 57.6% lower in England, Scotland and Wales relative to April-June 2019 (pre-pandemic). By April-June 2023, the number of eligible donors had recovered to 87.4%, 64.2% and 110.3%, respectively, of their levels in 2019. The consent rate in England, Scotland and Wales reduced from 68.3%, 63.0% and 63.6% in April-June 2019 to 63.2%, 60.5% and 56.3% in April-June 2023.
Conclusions:
While the UK organ donation system shows signs of recovery from the COVID-19 pandemic, the number of eligible potential donors and consent rates remain below their pre-pandemic levels.
AB - Background:
In May 2020, England implemented soft ‘opt-out’ or ‘deemed consent’ for deceased donation with the intention of raising consent rates. However, this coincided with the COVID-19 pandemic, making it difficult to assess the early impact of the law change. Wales and Scotland changed their organ donation legislation to implement soft opt-out systems in 2015 and 2021 respectively. This study provides a descriptive analysis of changes in consent and transplant rates for deceased organ donation in England, Scotland and Wales.
Methods:
Logistic regression and descriptive trend analysis were employed to assess the probability of a patient who died in critical care becoming a donor, and to report consent rates using data, respectively, from the Intensive Care National Audit and Research Centre (ICNARC) in England from 1 April 2014 to 30 September 2021, and from the Potential Donor Audit for England, Scotland and Wales from April 2010 to June 2023.
Results:
The number of eligible donors in April-June 2020 were 56.5%, 59.3% and 57.6% lower in England, Scotland and Wales relative to April-June 2019 (pre-pandemic). By April-June 2023, the number of eligible donors had recovered to 87.4%, 64.2% and 110.3%, respectively, of their levels in 2019. The consent rate in England, Scotland and Wales reduced from 68.3%, 63.0% and 63.6% in April-June 2019 to 63.2%, 60.5% and 56.3% in April-June 2023.
Conclusions:
While the UK organ donation system shows signs of recovery from the COVID-19 pandemic, the number of eligible potential donors and consent rates remain below their pre-pandemic levels.
KW - COVID-19/epidemiology
KW - England/epidemiology
KW - Humans
KW - Informed Consent/legislation & jurisprudence
KW - Male
KW - Pandemics
KW - SARS-CoV-2
KW - Scotland/epidemiology
KW - Tissue Donors
KW - Tissue and Organ Procurement/legislation & jurisprudence
KW - Wales/epidemiology
U2 - 10.1371/journal.pone.0306541
DO - 10.1371/journal.pone.0306541
M3 - Article
C2 - 39083454
SN - 1932-6203
VL - 19
JO - PLoS ONE
JF - PLoS ONE
IS - 7
M1 - e0306541
ER -