Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

Connor  Howe; David  MacLeod; Liisa Wainman; Sam Oliver; Philip  Ainslie

doi:10.1016/j.chest.2020.04.017

Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

Connor Howe, David MacLeod, Liisa Wainman, Sam Oliver, Philip Ainslie

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Abstract

Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.

Original language	English
Pages (from-to)	1644-1650
Journal	Chest
Volume	158
Issue number	4
Early online date	25 Apr 2020
DOIs	https://doi.org/10.1016/j.chest.2020.04.017
Publication status	Published - 1 Oct 2020

Keywords

exercise
hypoxia
noninvasive
pulmonary gas exchange
validation

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abstract = "Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.",

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Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

Abstract

Keywords

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