Synthetic studies towards analogues of ptilomycalin A

Abstract

The thesis describes three synthetic approaches to analogues of ptilomycalin A and studies their biological activity. The analogue 181 was prepared by a linear synthetic route and this compound was found to be, as expected, biologically largely inactive. A convergent synthetic approach was applied to the synthesis of the analogues 214, 191 and 192.

Date of Award	Jan 2004
Original language	English
Awarding Institution	Bangor University
Supervisor	Paddy Murphy (Supervisor)