[Pre-Aug 2018] North Wales Centre for Primary Care Research

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2019
Published

Pragmatic methods for reviewing exceptionally large bodies of evidence: systematic mapping review and overview of systematic reviews using lung cancer survival as an exemplar
Lewis, R., Hendry, M., Din, N., Stanciu, M. A., Nafees, S., Hendry, A., Teoh, Z. H., Lloyd, T., Parsonage, R., Neal, R. D., Collier, G. & Huws, D. W., 16 Jul 2019, In: Systematic Reviews. 8, 1, 171.
Research output: Contribution to journal › Article › peer-review
Published

Preserved re-experience of discrete emotions: Amnesia and executive function
Stanciu, M. A., Rafal, R. D. & Turnbull, O. H., Jun 2019, In: Journal of Neuropsychology. 13, 2, p. 305-327
Research output: Contribution to journal › Article › peer-review
2018
Published

Diagnostic routes and time intervals for patients with colorectal cancer in 10 international jurisdictions; findings from a cross-sectional study from the International Cancer Benchmarking Partnership (ICBP)
Weller, D., Menon, U., Falborg, A. Z., Jensen, H., Barisic, A., Knudsen, A. K., Bergin, R. J., Brewster, D., Cairnduff, V., Gavin, A. T., Grunfeld, E., Harland, E., Lambe, M., Law, R-J., Lin, Y., Malmberg, M., Tober, D., Neal, R., White, V., Harrison, S. & Reguilon, I., 27 Nov 2018, In: BMJ Open. 8, 11, e023870.
Research output: Contribution to journal › Article › peer-review
Published

Development of an intervention to expedite cancer diagnosis through primary care: a protocol
Stanciu, M. A., Law, R-J., Nafees, S., Hendry, M., Yeo, S. T., Hiscock, J., Lewis, R., Edwards, R., Williams, N., Brain, K., Brocklehurst, P., Carson-Stevens, A., Dolwani, S., Emery, J., Hamilton, W., Hoare, Z., Lyratzopoulos, G., Rubin, G., Smits, S., Vedsted, P., Walter, F., Wilkinson, C. & Neal, R., Oct 2018, In: British Journal of General Practice. 2, 3, bjgpopen18X101595.
Research output: Contribution to journal › Article › peer-review
2016
Published

Improving early diagnosis of symptomatic cancer
Hamilton, W., Walter, F. M., Rubin, G. & Neal, R., Dec 2016, In: Nature Reviews Clinical Oncology. 13, 12, p. 740-749
Research output: Contribution to journal › Article › peer-review
Published

Trial of Optimal Personalised Care After Treatment for Gynaecological cancer (TOPCAT-G): a study protocol for a randomised feasibility trial
Pye, K., Totton, N., Stuart, N., Whitaker, R., Morrison, V., Edwards, R. T., Yeo, S. T., Timmis, L. J., Butterworth, C., Hall, L., Rai, T., Hoare, Z., Neal, R. D., Wilkinson, C. & Leeson, S., 23 Nov 2016, In: Pilot and Feasibility Studies. 2, 67.
Research output: Contribution to journal › Article › peer-review
Published

An investigation of routes to cancer diagnosis in 10 international jurisdictions, as part of the International Cancer Benchmarking Partnership: Survey development and implementation
Weller, D., Vedsted, P., Anandan, C., Zalounina, A., Fourkala, E. O., Desai, R., Liston, W., Jensen, H., Barisic, A., Gavin, A., Grunfeld, E., Lambe, M., Law, R-J., Malmberg, M., Neal, R. D., Kalsi, J., Turner, D., White, V., Bomb, M. & Menon, U., 1 Jul 2016, In: BMJ Open. 6, 7
Research output: Contribution to journal › Article › peer-review
Published

Qualitative "trial-sibling" studies and "unrelated" qualitative studies contributed to complex intervention reviews
Noyes, J., Hendry, M., Lewin, S., Glenton, C., Chandler, J. & Rashidian, A., Jun 2016, In: Journal of Clinical Epidemiology. 74, p. 133-143
Research output: Contribution to journal › Article › peer-review
Published

Symptoms, unmet needs, psychological well-being and health status in survivors of prostate cancer: implications for redesigning follow-up
Watson, E., Shinkins, B., Frith, E., Neal, D., Hamdy, F., Walter, F., Weller, D., Wilkinson, C., Faithfull, S., Wolstenholme, J., Sooriakumaran, P., Kastner, C., Campbell, C., Neal, R., Butcher, H., Matthews, M., Perera, R. & Rose, P., Jun 2016, In: BJUI International. 117, 6B, p. E10-E19
Research output: Contribution to journal › Article › peer-review
Published

Talking about human papillomavirus and cancer: Protocol for a patient-centred study to develop scripted consultations
Hendry, M., Pasterfield, D., Adams, R., Evans, M., Fiander, A., Robling, M., Campbell, C., Makin, M., Gollins, S., Hiscock, J., Nafees, S., Bekkers, M., Rose, J., Williams, O., Stanley, M. & Wilkinson, C. E., 25 Apr 2016, In: BMJ Open.
Research output: Contribution to journal › Article › peer-review
Published

Intervention Now to Eliminate Repeat Unintended Pregnancy in Teenagers (INTERUPT): a systematic review of intervention effectiveness and cost-effectiveness, and qualitative and realist synthesis of implementation factors and user engagement
Whitaker, R., Hendry, M., Aslam, R., Booth, A., Carter, B., Charles, J., Craine, N., Edwards, R., Noyes, J., Ntambwe, L. I., Pasterfield, D., Rycroft-Malone, J. & Williams, N., 1 Mar 2016, In: Health Technology Assessment. 20, 16
Research output: Contribution to journal › Article › peer-review
Published

Symptoms of adult chronic and acute Leukaemia before diagnosis: Large primary care case-control studies using electronic records
Shephard, E. A., Neal, R. D., Rose, P. W., Walter, F. M. & Hamilton, W. T., 1 Mar 2016, In: British Journal of General Practice. 66, 644, p. e171-e181
Research output: Contribution to journal › Article › peer-review
Published

International variation in adherence to referral guidelines for suspected cancer: a secondary analysis of survey data
Nicholson, B. D., Mant, D., Neal, R. D., Hart, N., Hamilton, W., Shinkins, B., Rubin, G. & Rose, P. W., 7 Jan 2016, In: British Journal of General Practice. 66, 643, p. E106-E113
Research output: Contribution to journal › Article › peer-review
Published

An Association of Cancer Physicians' strategy for improving services and outcomes for cancer patients
Neal, R. D., Baird, R., Banks, I., Cameron, D., Chester, J., Earl, H., Flannagan, M., Januszewski, A., Kennedy, R., Payne, S., Samuel, E., Taylor, H., Agarwal, R., Ahmed, S., Archer, C., Board, R., Carser, J., Copson, E., Cunningham, D., Coleman, R., Glaser, A., Griffiths, R., Hall, G., Hall, M., Harari, D., Hawkins, M., Hill, M., Johnson, P., Jones, A., Kalsi, T., Karapanagiotou, E., Kemp, Z., Mansi, J., Marshall, E., Mitchell, A., Moe, M., Michie, C., Neal, R., Newsom-Davis, T., Norton, A., Osborne, R., Patel, G., Radford, J., Ring, A., Shaw, E., Skinner, R., Stark, D., Turnbull, S., Velikova, G., White, J., Young, A., Joffe, J. & Selby, P., 5 Jan 2016, In: Ecancermedical Science. 10, 608
Research output: Contribution to journal › Article › peer-review
Published

In Vitro Evaluation of the Interaction of Dextrin-Colistin Conjugates with Bacterial Lipopolysaccharide
Roberts, J. L., Cattoz, B., Schweins, R., Beck, K., Thomas, D. W., Griffiths, P. C. & Ferguson, E. L., 5 Jan 2016, In: Journal of Medicinal Chemistry. 59, 2, p. 647-654
Research output: Contribution to journal › Article › peer-review
2015
Published

Symptoms, ultrasound imaging and biochemical markers alone or in combination for the diagnosis of ovarian cancer in women with symptoms suspicious of ovarian cancer
Rai, N., Campaneria, R., Snell, K., Mallett, S., Bayliss, S. E., Neal, R. D., Balogun, M., Kehoe, S., Deeks, J. K., Sundar, S. & Davenport, C., 7 Dec 2015, In: Cochrane Library. 2015, 12, CD011964.
Research output: Contribution to journal › Article › peer-review
Published

The Effects of Aerobic and Resistance Exercise on Markers of Large Joint Health in Stable Rheumatoid Arthritis Patients: A pilot study
Law, R-J., Saynor, Z. L., Gabbitas, J., Jones, J., Kraus, A., Breslin, A., Maddison, P. J. & Thom, J. M., 7 Dec 2015, In: Musculoskeletal Care. 13, 4, p. 222-235
Research output: Contribution to journal › Article › peer-review
Published

The Effects of Aerobic and Resistance Exercise on Markers of Large Joint Health in Stable Rheumatoid Arthritis Patients: A Pilot Study
Law, R-J., Saynor, Z. L., Gabbitas, J., Jones, J., Kraus, A., Breslin, A., Maddison, P. J. & Thom, J. M., Dec 2015, In: Musculoskeletal Care. 13, 4, p. 222-235 14 p.
Research output: Contribution to journal › Article › peer-review
Published

Health professionals’ perspectives on exercise referral and physical activity promotion in primary care: Findings from a process evaluation of the National Exercise Referral Scheme in Wales
Wilkinson, C. E., Din, N. U., Moore, G. F., Murphy, S., Wilkinson, C. & Williams, N. H., 1 Nov 2015, In: Health Education Journal. 74, 6, p. 743-757
Research output: Contribution to journal › Article › peer-review
Published

For which cancers might patients benefit most from expedited symptomatic diagnosis? Construction of a ranking order by a modified Delphi technique
Hamilton, W., Stapley, S., Campbell, C., Lyratzopoulos, G., Rubin, G. & Neal, R. D., 30 Oct 2015, In: BMC Cancer. 15, 820
Research output: Contribution to journal › Article › peer-review
Published

School-based Brief Psychoeducational Intervention To Raise Adolescent Cancer Awareness and Address Barriers to Seeking Medical Help about Cancer: Cluster Randomized Controlled Trial
Hubbard, G., MacMillan, I., Forbat, L., Neal, R. D., O'Carroll, R. E., Haw, S., Rauchaus, P. & Kyle, R. G., 27 Oct 2015, In: Psycho-Oncology.
Research output: Contribution to journal › Article › peer-review
Published

Diagnostic value of symptoms of oesophagogastric cancers in primary care: a systematic review and meta-analysis
Astin, M. P., Martins, T., Welton, N., Neal, R. D., Rose, P. W. & Hamilton, W., 1 Oct 2015, In: British Journal of General Practice. 65, 639
Research output: Contribution to journal › Article › peer-review
Published

Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence
Le Noury, J. C., Nardo, J. M., Healy, D., Jureidini, J., Raven, M., Tufanaru, C. & Abi-Jaoude, E., 16 Sept 2015, In: BMJ. 351, h4320.
Research output: Contribution to journal › Article › peer-review
Published

Diagnosis of Ovarian Cancer
Sundar, S., Neal, R. D. & Kehoe, S., 1 Sept 2015, In: BMJ. 351, p. h4443
Research output: Contribution to journal › Article › peer-review
Published

The complexity and difficulty of diagnosing lung cancer: findings from a national primary-care study in Wales
Neal, R. D., Robbie, I. J., Lewis, M., Williamson, I. & Hanson, J., 1 Sept 2015, In: Primary Health Care Research and Development. 16, 05, p. 436-449
Research output: Contribution to journal › Article › peer-review
Published

The expanding role of primary care in cancer control
Wilkinson, C. E., Rubin, G., Berendsen, A., Crawford, S. M., Dommett, R., Earle, C., Emery, J., Fahey, T., Grassi, L., Grunfeld, E., Gupta, S., Hamilton, W., Hiom, S., Hunter, D., Lyratzopoulos, G., Maclead, U., Mason, R., Mitchell, G., Neal, R. D., Peake, M., Roland, M., Seifert, B., Sisler, J., Sussman, J., Taplin, S., Vedsted, P., Voruganti, T., Walter, F., Wardle, J., Watson, E., Weller, D., Wender, R., Whelan, J., Whitlock, J., Wilkinson, C., de Wit, N. & Zimmerman, C., 1 Sept 2015, In: Lancet Oncology. 16, 12, p. 1231–1272
Research output: Contribution to journal › Article › peer-review
Published

A pilot randomised controlled trial of personalised care after treatment for prostate cancer (TOPCAT-P): nurse-led holistic-needs assessment and individualised psychoeducational intervention: study protocol
Evans, R. J., Hoare, Z. S., Wilkinson, C. E., Stanciu, M. A., Makin, M., Watson, E., Bulger, J., Evans, R., Hiscock, J., Hoare, Z., Edwards, R. T., Neal, R. D. & Wilkinson, C., 25 Jun 2015, In: BMJ Open. 5, 6
Research output: Contribution to journal › Article › peer-review
Published

Women’s experiences of cervical ripening as inpatients on an antenatal ward
Brown, S. J. & Furber, C. M., 24 Jun 2015, In: Sexual and Reproductive Healthcare. 6, 4, p. 219-225
Research output: Contribution to journal › Article › peer-review
Published

‘Carrying on the way we are, is becoming shambolic’ – An interview study with prostate cancer specialists about their usual practice of follow-up
Stanciu, M. A., Bulger, J. K., Hiscock, J., Neal, R. D., Stanciu, A., Makin, M. & Wilkinson, C., 2 Jun 2015, In: Journal of Clinical Urology. 8, 4, p. 240-245
Research output: Contribution to journal › Article › peer-review
Published

Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey
Rose, P. W., Rubin, G., Perera-Salazar, R., Almberg, S. S., Barisic, A., Dawes, M., Grunfeld, E., Hart, N., Neal, R. D., Pirotta, M., Sisler, J., Konrad, G., Toftegaard, B. S., Thulesius, H., Vedsted, P., Young, J., Hamilton, W. & The ICBP Module 3 Working Group., N. V., 27 May 2015, In: BMJ Open. 5, 5
Research output: Contribution to journal › Article › peer-review
Published

Age and Gender Variations in Cancer Diagnostic Intervals in 15 Cancers: Analysis of Data from the UK Clinical Practice Research Datalink
Din, N. U., Ukoumunne, O. C., Rubin, G., Hamilton, W., Carter, B., Stapley, S. & Neal, R. D., 15 May 2015, In: PLoS ONE. 10, 5
Research output: Contribution to journal › Article › peer-review
Published

Interview with Dr David Healy, 13 February 2013
Peters, K. R., Katz, S. & Healy, D., 1 May 2015, In: Dementia. 14, 3, p. 361-369
Research output: Contribution to journal › Article › peer-review
Published

Quantifying the risk of Hodgkin lymphoma in symptomatic primary care patients aged ≥40 years: a case–control study using electronic records
Shephard, E. A., Neal, R. D., Rose, P. W., Walter, F. M. & Hamilton, W. T., 1 May 2015, In: British Journal of General Practice. p. e289-e294
Research output: Contribution to journal › Article › peer-review
Published

Quantifying the risk of non-Hodgkin lymphoma in symptomatic primary care patients aged ≥40 years: a large case–control study using electronic records
Shephard, E. A., Neal, R. D., Rose, P. W., Walter, F. M. & Hamilton, W. T., 1 May 2015, In: British Journal of General Practice. 65, 634, p. e281-e288
Research output: Contribution to journal › Article › peer-review
Published

What are the experiences of cancer care in gay, lesbian and bisexual patients, and how do these differ from heterosexual cancer patients?
Plumpton, C. O., Neal, R. D., Hulbert-Williams, N., McHugh, R., Semlyen, J., Flowers, P., Storey, L., Ream, E. & Neal, R., 28 Apr 2015, In: Psycho-Oncology. 24, S1, p. 2-3
Research output: Contribution to journal › Article › peer-review
Published

Has evidence-based medicine left quackery behind?
Naudet, F., Falissard, B., Boussageon, R. & Healy, D., 1 Apr 2015, In: Internal and Emergency Medicine. 10, 5, p. 631-634
Research output: Contribution to journal › Article › peer-review
Published

Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review
Neal, R. D., Tharmanathan, P., France, B., Din, N. U., Cotton, S., Fallon-Ferguson, J., Hamilton, W., Hendry, A., Hendry, M., Lewis, R., Macleod, U., Mitchell, E. D., Pickett, M., Rai, T., Shaw, K., Stuart, N., Tørring, M. L., Wilkinson, C., Williams, B., Williams, N. & Emery, J., 31 Mar 2015, In: British Journal of Cancer. 112 , Suppl 1, p. S92-107
Research output: Contribution to journal › Article › peer-review
Published

The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers
Lyratzopoulos, G., Saunders, C. L., Abel, G. A., McPhail, S. M., Neal, R. D., Wardle, J. & Rubin, G. P., 3 Mar 2015, In: British Journal of Cancer. 112, p. S35–S40
Research output: Contribution to journal › Article › peer-review
Published

Quantifying the risk of multiple myeloma from symptoms reported by primary care patients: a large case-control study using electronic records
Shepard, E. A., Neal, R. D., Rose, P., Walter, F. M. & Hamilton, W. T., 1 Feb 2015, In: British Journal of General Practice. 65, 631, p. E106-E113
Research output: Contribution to journal › Article › peer-review
Published

Impact of investigations in general practice on timeliness of referral for patients subsequently diagnosed with cancer: analysis of national primary care audit data
Rubin, G. P., Saunders, C. L., Abel, G. A., McPhail, S., Lyratzopoulos, G. & Neal, R. D., 20 Jan 2015, In: British Journal of Cancer. 112, p. 676-687
Research output: Contribution to journal › Article › peer-review
2014
Published

Dextrin-colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections
Ferguson, E. L., Azzopardi, E., Roberts, J. L., Walsh, T. R. & Thomas, D. W., 31 Oct 2014, In: Molecular Pharmaceutics. 11, 12, p. 4437-47 11 p.
Research output: Contribution to journal › Article › peer-review
Published

Cancer symptom awareness and barriers to medical help seeking in Scottish adolescents: a cross-sectional study
Hubbard, G., Macmillan, I., Canny, A., Forbat, L., Neal, R. D., O'Carroll, R. E., Haw, S. & Kyle, R. G., 29 Oct 2014, In: BMC Public Health. 14, 1117
Research output: Contribution to journal › Article › peer-review
Published

Achieving earlier diagnosis of symptomatic cervical cancer
Walter, F. M., Mwaka, A. D. & Neal, R. D., 1 Oct 2014, In: British Journal of General Practice. 64, p. 495-496
Research output: Contribution to journal › Article › peer-review
Published

Research into practice: prompt diagnosis of cancer in primary care
Rubin, G., Walter, F., Emery, J., Neal, R. D., Hamilton, W. & Wardle, J., 1 Aug 2014, In: British Journal of General Practice. 64, 625, p. 428-430
Research output: Contribution to journal › Article › peer-review
Published

A stepped wedge cluster randomized control trial of dried blood spot testing to improve the uptake of hepatitis C antibody testing within UK prisons
Craine, N., Whitaker, R., Perrett, S., Zou, L., Hickman, M. & Lyons, M., 24 Jul 2014, In: European Journal of Public Health. 25, 2, p. 351-357
Research output: Contribution to journal › Article › peer-review
Published

Cost-effectiveness of different strategies to manage patients with sciatica
Fitzimmons, D., Phillips, C. J., Bennett, H., Jones, M., Williams, N. H., Lewis, R., Sutton, A., Matar, H. E., Din, N. U., Burton, K., Nafees, S., Hendry, M., Rickard, I. & Wilkinson, C. E., Jul 2014, In: Pain. 155, 7, p. 1318-1327 10 p.
Research output: Contribution to journal › Article › peer-review
Published

Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation
Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Jul 2014, In: Health Technology Assessment. 18, 48, p. 1-159
Research output: Contribution to journal › Article › peer-review
Published

Development of a survey instrument to investigate the primary care factors related to differences in cancer diagnosis between international jurisdictions
Rose, P. W., Hamilton, W., Aldersey, K., Barisic, A., Dawes, M., Foot, C., Grunfeld, E., Hart, N., Neal, R. D., Pirotta, M., Sisler, J., Thulesius, H., Vedsted, P., Young, J. & Rubin, G., 17 Jun 2014, In: BMC Family Practice. 2014, 15, p. 122
Research output: Contribution to journal › Article › peer-review
Published

PROSPECTIV—a pilot trial of a nurse-led psychoeducational intervention delivered in primary care to prostate cancer survivors: study protocol for a randomised controlled trial
Wilkinson, C. E., Watson, E., Rose, P., Frith, E., Hamdy, F., Neal, D., Kastner, C., Russell, S., Walter, F. M., Faithfull, S., Wolstenholme, J., Perera, R., Weller, D., Campbell, C., Wilkinson, C., Neal, R. D., Sooriakumaran, P., Butcher, H. & Matthews, M., 22 May 2014, In: BMJ Open. 4, 5, e005186.
Research output: Contribution to journal › Article › peer-review
Published

Healthy eating and lifestyle in pregnancy (HELP): a protocol for a cluster randomised trial to evaluate the effectiveness of a weight management intervention in pregnancy
Williams, N. H., John, E., Cassidy, D. M., Playle, R., Jewell, K., Cohen, D., Duncan, D., Newcombe, R. G., Busse, M., Owen-Jones, E., Williams, N., Longo, M., Avery, A. & Simpson, S. A., 10 May 2014, In: BMC Public Health. 14, 439
Research output: Contribution to journal › Article › peer-review

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