Research Portal

Dr Ramsay Mcfarlane

Senior Lecturer in Biomedical Sciences (Medical & Molecular Genetics)

Affiliations

Contact info

Location: Brambell, Room 405

Phone: 2360

Email: r.macfarlane@bangor.ac.uk

Position: Senior Lecturer / Research Group Leader / Deputy Head of School – Research

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  1. Published

    tRNA genes in eukaryotic genome organization and reorganization.

    Mcfarlane, R. J., McFarlane, R. J. & Whitehall, S. K., 1 Oct 2009, In: Cell Cycle. 8, 19, p. 3102-3106

    Research output: Contribution to journal › Article › peer-review

  2. Published

    Translin-Trax: Considerations for Oncological Therapeutic Targeting

    McFarlane, R. J. & Wakeman, J. A., Jun 2020, In: Trends in Cancer. 6, 6, p. 450-453 4 p.

    Research output: Contribution to journal › Article › peer-review

  3. Published

    Translin facilitates RNA polymerase II dissociation and suppresses genome instability during RNase H2- and Dicer-deficiency

    Gomez Escobar, N., Alsaiari, A., Alahmadi, H. A. S., Alzahrani, O., Vernon, E., Althagafi, H., Almobadel, N., Pryce, D., Wakeman, J. & Mcfarlane, R., 17 Jun 2022, In: PLOS Genetics. 18, 6, e1010267.

    Research output: Contribution to journal › Article › peer-review

  4. Published

    Translin and Trax differentially regulate telomere-associated transcript homeostasis

    Gomez Escobar, N., Almobadel, N., Alzahrani, O., Feichtinger, J., Planells Palop, V., Alshehri, Z., Thallinger, G. G., Wakeman, J. & Mcfarlane, R., 10 May 2016, In: Oncotarget. 12 p.

    Research output: Contribution to journal › Article › peer-review

  5. Published

    The unique centromeric chromatin structure of Schizosaccharomyces pombe is maintained during meiosis.

    Mcfarlane, R. J., Smirnova, J. B. & McFarlane, R. J., 31 May 2002, In: Journal of Biological Chemistry. 277, 22, p. 19817-19822

    Research output: Contribution to journal › Article › peer-review

  6. Published

    The many facets of the Tim-Tipin protein families' roles in chromosome biology.

    Mcfarlane, R. J., McFarlane, R. J., Mian, S. & Dalgaard, J. Z., 15 Feb 2010, In: Cell Cycle. 9, 4, p. 700-705

    Research output: Contribution to journal › Article › peer-review

  7. Published

    The immortal strand hypothesis: still non-randomly segregating opinion.

    Wakeman, J., Hmadcha, A., Soria, B. & Mcfarlane, R., 23 Mar 2012, In: Biomolecular Concepts. 3, 3, p. 203-211

    Research output: Contribution to journal › Article › peer-review

  8. Published

    The genetics of the repaor of 5-azacytidine-mediated DNA damage in the fission yeast Schizosaccharomyces pombe.

    Hegde, V., Mcfarlane, R., Taylor, E. M. & Price, C., 1 Jun 1996, In: Molecular Genetics and Genomics. 251, 4, p. 483-492

    Research output: Contribution to journal › Article › peer-review

  9. Published

    The Meiotic Recombination Hotspots of Schizosaccharomyces pombe

    Pryce, D. & Mcfarlane, R. J., 1 Jan 2009, In: Meiosis. 5, p. 1-13

    Research output: Contribution to journal › Article › peer-review

  10. Published

    SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe.

    Mcfarlane, R. J., Spirek, M., Estreicher, A., Csaszar, E., Wells, J., McFarlane, R. J., Watts, F. Z. & Loidl, J., 1 Feb 2010, In: Chromosoma. 119, 1, p. 59-72

    Research output: Contribution to journal › Article › peer-review

  11. Published

    S-pombe meiotic linear elements contain proteins related to synaptonemal complex components

    Lorenz, A., Wells, J. L., Pryce, D., Novatchkova, M., Eisenhaber, F., Mcfarlane, R. J. & Loidl, J., 28 Jun 2004, In: Journal of Cell Science. 117, 15, p. 3343-3351

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1

    Pryce, D. W., Ramayah, S., Jaendling, A. & Mcfarlane, R., 24 Mar 2009, In: Proceedings of the National Academy of Sciences of the USA. 106, 12, p. 4770-4775

    Research output: Contribution to journal › Article › peer-review

  13. Published

    Psc3 cohesion of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms

    Ilyushik, E., Pryce, D., Walerych, D., Riddell, T., Wakeman, J. A., McInerny, C. J. & Mcfarlane, R., Jul 2005, In: Biological Chemistry. 386, 7, p. 613-621

    Research output: Contribution to journal › Article › peer-review

  14. Published
  15. Published

    Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis.

    Jessen, J. R., Meng, A., Mcfarlane, R., Paw, B. H., Zon, L. I., Smith, G. R. & Lin, S., 1998, In: Proceedings of the National Academy of Sciences of the USA. 95, 9, p. 5121 5126 p.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers

    Mcfarlane, R. J., Feichtinger, J., Larcombe, L. & McFarlane, N. V., 15 May 2014, In: International Journal of Cancer. 134, 10, p. 2359-2365

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.

    Stuart, N. S., Wakeman, J., Mcfarlane, R. J., Feichtinger, J., Aldeailej, I., Anderson, R., Almutairi, M., Almatrafi, A., Alsiwiehri, N., Griffiths, K., Stuart, N., Wakeman, J. A., Larcombe, L. & McFarlane, R. J., 13 Aug 2012, In: Oncotarget. 3, 8, p. 843-853

    Research output: Contribution to journal › Article › peer-review

  18. Published

    Meta-analysis of cancer microarray data sets reveals a germ line expression profile in ovarian cancers: new biomarkers and potential drug targets

    Mcfarlane, R. J. & McFarlane, R., 15 Aug 2015, In: Clinical Cancer Research. 21, 16

    Research output: Contribution to journal › Article › peer-review

  19. Published

    Meiotic gene activation in somatic and germ cell tumours

    Mcfarlane, R. & Feichtinger, J., Jul 2019, In: Andrology. 7, 4, p. 415-427 13 p.

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Meiosis-like functions in oncogenesis: a new view of cancer.

    Mcfarlane, R. & Wakeman, J., Nov 2017, In: Cancer Research. 77, 21, p. 5712-5716

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Linear element-independent meiotic recombination in Schizosaccharomyces pombe.

    Mcfarlane, R. J., Wells, J. L., Pryce, D. W., Estreicher, A., Loidl, J. & McFarlane, R. J., 1 Nov 2006, In: Genetics. 174, 3, p. 1105-1114

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2'-deoxycytidine

    Almatrafi, A., Feichtinger, J., Vernon, E. G., Escobar, N. G., Wakeman, J. A., Larcombe, L. D. & McFarlane, R. J., 10 Nov 2014, In: Oncoscience. 1, 11, p. 745-750 6 p.

    Research output: Contribution to journal › Article › peer-review

  23. Published

    Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis

    Planells Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G. G., Alsiwiehri, N., Almutairi, M., Parry, L., Wakeman, J. & Mcfarlane, R., 26 Apr 2017, In: Molecular Cancer. 16, 1, p. 1-18 84.

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Homologous chromosome pairing in Schizosaccharomyces pombe

    Mcfarlane, R. J., Wells, J. L., Pryce, D. W. & McFarlane, R. J., 15 Oct 2006, In: Yeast. 23, 13, p. 977-989

    Research output: Contribution to journal › Article › peer-review

  25. Published

    Germline/meiotic genes in cancer: new dimensions

    Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 19 Mar 2015, In: Cell Cycle. 14, 6, p. 791-792

    Research output: Contribution to journal › Article › peer-review

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