Dr Ramsay Mcfarlane

Senior Lecturer in Biomedical Sciences (Medical & Molecular Genetics)

Contact info

Location: Brambell, Room 405

Phone: 2360

Email: r.macfarlane@bangor.ac.uk

Position: Senior Lecturer / Research Group Leader / Deputy Head of School – Research

  1. Article › Research › Peer-reviewed
  2. Published

    5-azacytidine treatment of the fission yeast leads to cytotxicity and cell cycle arrest.

    Taylor, E. M., Mcfarlane, R. & Price, C., 1996, In: Molecular Genetics and Genomics. 253, 1-2, p. 128-137

    Research output: Contribution to journalArticlepeer-review

  3. Published

    A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets

    Sammut, S. J., Feichtinger, J., Stuart, N. S., Wakeman, J., Larcombe, L. & Mcfarlane, R. J., 6 May 2014, In: Oncoscience. 1, 5, p. 349-359

    Research output: Contribution to journalArticlepeer-review

  4. Published

    A role for recombination in centromere function.

    Mcfarlane, R. J., McFarlane, R. J. & Humphrey, T. C., 1 May 2010, In: Trends in Genetics. 26, 5, p. 209-213

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.

    Mcfarlane, R. J., Jaendling, A. & McFarlane, R. J., 15 Jul 2010, In: Biochemical Journal. 429, 2, p. 225-234

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

    Jezkova, J., Williams, J. S., Pinto, F., Sammut, S. J., Williams, G. T., Gollins, S., Mcfarlane, R. J., Reis, R. M. & Wakeman, J., 5 Feb 2016, In: Oncotarget. 2016, 7, p. 11478-11486

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway

    Mcfarlane, R. J., Gollins, S. W., Wakeman, J., Jezkova, J., Williams, J. S., Jones-Hutchins, F., Sammut, S. J., Gollins, S., Cree, I., Coupland, S., McFarlane, R. J. & Wakeman, J. A., 21 May 2014, In: Oncotarget. 5, 11, p. 3813-3822

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Brachyury: Strategies for Drugging an Intractable Cancer Therapeutic Target

    Robinson, H., McFarlane, R. J. & Wakeman, J. A., Apr 2020, In: Trends in cancer. 6, 4, p. 271-273 3 p.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Cancer germline gene activation: Friend or foe?

    Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 23 Jun 2014, In: Cell Cycle. 13, 14, p. 2151-2152

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Cancer/Testis Antigens and Colorectal Cancer

    Sammut, S. J., Wakeman, J., Mcfarlane, R. J., Sammut, J., Wakeman, J. A., Stuart, N. & McFarlane, R. J., 13 Jun 2013, In: Journal of Genetic Syndromes and Gene Therapy. 4, 5, p. 149

    Research output: Contribution to journalArticlepeer-review

  11. Published

    CancerEST: a web-based tool for automatic meta-analysis of public EST data

    Mcfarlane, R. J., Feichtinger, J., McFarlane, R. J. & Larcombe, L. D., 27 Feb 2014, In: Database: The Journal of Biological Databases and Curation. 2014

    Research output: Contribution to journalArticlepeer-review

  12. Published

    CancerMA: a web-based tool for automatic meta-analysis of public cancer microarray data.

    Feichtinger, J., Mcfarlane, R. & Larcombe, L., 15 Dec 2012, In: Database: The Journal of Biological Databases and Curation. 2012, bas055.

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.

    Mcfarlane, R., Carr, A. M. & Price, C., 1 Jul 1997, In: Molecular Genetics and Genomics. 255, 3, p. 332-340

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Comparative proteomic analysis reveals differential expression of Hsp25 following the directed differentiation of mouse embryonic stem cells.

    Wakeman, J., Mcfarlane, R. J., Battersby, A., Jones, R. D., Lilley, K. S., McFarlane, R. J., Braig, H. R., Allen, N. D. & Wakeman, J. A., 1 Feb 2007, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 2, p. 147-156

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe.

    Mcfarlane, R. J., Pryce, D. W., Lorenz, A., Smirnova, J. B., Loidl, J. & McFarlane, R. J., 1 May 2005, In: Genetics. 170, 1, p. 95-106

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX.

    Mcfarlane, R. J., Jaendling, A., Ramayah, S., Pryce, D. W. & McFarlane, R. J., 1 Feb 2008, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 2, p. 203-213

    Research output: Contribution to journalArticlepeer-review

  17. Published

    Germline/meiotic genes in cancer: new dimensions

    Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 19 Mar 2015, In: Cell Cycle. 14, 6, p. 791-792

    Research output: Contribution to journalArticlepeer-review

  18. Published

    Homologous chromosome pairing in Schizosaccharomyces pombe

    Mcfarlane, R. J., Wells, J. L., Pryce, D. W. & McFarlane, R. J., 15 Oct 2006, In: Yeast. 23, 13, p. 977-989

    Research output: Contribution to journalArticlepeer-review

  19. Published

    Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis

    Planells Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G. G., Alsiwiehri, N., Almutairi, M., Parry, L., Wakeman, J. & Mcfarlane, R., 26 Apr 2017, In: Molecular Cancer. 16, 1, p. 1-18 84.

    Research output: Contribution to journalArticlepeer-review

  20. Published

    Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2'-deoxycytidine

    Almatrafi, A., Feichtinger, J., Vernon, E. G., Escobar, N. G., Wakeman, J. A., Larcombe, L. D. & McFarlane, R. J., 10 Nov 2014, In: Oncoscience. 1, 11, p. 745-750 6 p.

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Linear element-independent meiotic recombination in Schizosaccharomyces pombe.

    Mcfarlane, R. J., Wells, J. L., Pryce, D. W., Estreicher, A., Loidl, J. & McFarlane, R. J., 1 Nov 2006, In: Genetics. 174, 3, p. 1105-1114

    Research output: Contribution to journalArticlepeer-review

  22. Published

    Meiosis-like functions in oncogenesis: a new view of cancer.

    Mcfarlane, R. & Wakeman, J., Nov 2017, In: Cancer Research. 77, 21, p. 5712-5716

    Research output: Contribution to journalArticlepeer-review

  23. Published

    Meiotic gene activation in somatic and germ cell tumours

    Mcfarlane, R. & Feichtinger, J., Jul 2019, In: Andrology. 7, 4, p. 415-427 13 p.

    Research output: Contribution to journalArticlepeer-review

  24. Published

    Meta-analysis of cancer microarray data sets reveals a germ line expression profile in ovarian cancers: new biomarkers and potential drug targets

    Mcfarlane, R. J. & McFarlane, R., 15 Aug 2015, In: Clinical Cancer Research. 21, 16

    Research output: Contribution to journalArticlepeer-review

  25. Published

    Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.

    Stuart, N. S., Wakeman, J., Mcfarlane, R. J., Feichtinger, J., Aldeailej, I., Anderson, R., Almutairi, M., Almatrafi, A., Alsiwiehri, N., Griffiths, K., Stuart, N., Wakeman, J. A., Larcombe, L. & McFarlane, R. J., 13 Aug 2012, In: Oncotarget. 3, 8, p. 843-853

    Research output: Contribution to journalArticlepeer-review

  26. Published

    Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers

    Mcfarlane, R. J., Feichtinger, J., Larcombe, L. & McFarlane, N. V., 15 May 2014, In: International Journal of Cancer. 134, 10, p. 2359-2365

    Research output: Contribution to journalArticlepeer-review

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