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    Accepted author manuscript, 962 KB, PDF document

    Embargo ends: 9/01/20


Complex mixtures of natural dimycoloyl diarabinoglycerols isolated from mycobacteria have been shown to be both potent immune signalling agents and potentially valuable antigens in the serodiagnosis of mycobacterial infections. We now report the highly stereocontrolled synthesis of diacyl l-glycerol-(1′→1)-β-d-arabinofuranosyl-α-d-arabinofuranosides based on simple fatty acids and single defined synthetic mycolic acids. NMR analysis confirmed that the synthetic core was identical to that in natural mixtures.
Original languageEnglish
Pages (from-to)207-218
JournalChemistry and Physics of Lipids
Issue numberJuly
Early online date9 Jan 2019
Publication statusPublished - Jul 2019
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