Dyfrig Hughes - Research outputs

Published

An agenda for UK clinical pharmacology Pharmacoeconomics

Hughes, D. & Hughes, D. A., 1 Jun 2012, In: British Journal of Clinical Pharmacology. 73, 6, p. 968-972

Research output: Contribution to journal › Article › peer-review

Published

A new taxonomy for describing and defining adherence to medications

Holmes, E. A., Hughes, D., Morrison, V. L., Vrijens, B., De Geest, S., Hughes, D. A., Prezemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K. & Urquhart, J., 1 May 2012, In: British Journal of Clinical Pharmacology. 73, 5, p. 691-705

Research output: Contribution to journal › Article › peer-review

Published

The development of a QALY measure for epilepsy: NEWQOL-6D

Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

Research output: Contribution to journal › Article › peer-review

Published

An explanatory randomised controlled trial of a nurse-led, consultation-based intervention to support patients with adherence to taking glucose lowering medication for type 2 diabetes

Hughes, D., Farmer, A., Hardeman, W., Hughes, D. A., Prevost, A. T., Kim, Y., Craven, A., Oke, J., Boase, S., Selwood, M., Kellar, I., Graffy, J., Griffin, S., Sutton, S. & Kinmonth, A. L., 5 Apr 2012, In: BMC Family Practice. 13, 30

Research output: Contribution to journal › Article › peer-review

Published

Defining rewardable innovation in drug therapy

Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

Research output: Contribution to journal › Article › peer-review

Published

A Risk–Benefit Assessment of Prasugrel, Clopidogrel, and Genotype-Guided Therapy in Patients Undergoing Percutaneous Coronary Intervention

Hughes, D., Guzauskas, G. F., Hughes, D. A., Bradley, S. M. & Veenstra, D. L., 28 Mar 2012, In: Clinical Pharmacology and Therapeutics.

Research output: Contribution to journal › Article › peer-review

Published

Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.

Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Mar 2012, In: Pharmacoeconomics.

Research output: Contribution to journal › Article › peer-review

Published

The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76

Research output: Contribution to journal › Article › peer-review

Published

HTAs and rare diseases: How to assess their cost-effectiveness

Hughes, D., Phillips, C. J. & Hughes, D. A., 1 Nov 2011, In: Pharmaceuticals Policy and Law. 13, 3-4, p. 161-165

Research output: Contribution to journal › Article › peer-review

Published

Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

Research output: Contribution to journal › Article › peer-review

Published

Value-Based Pricing: Incentive for Innovation or Zero Net Benefit?

Hughes, D. & Hughes, D. A., 1 Sept 2011, In: Pharmacoeconomics. 29, 9, p. 731-735

Research output: Contribution to journal › Article › peer-review

Published

Involving colleagues can be challenging

Fargher, E. & Hughes, D., 2 Apr 2011, In: Pharmaceutical Journal. 286, p. 404

Research output: Contribution to journal › Letter › peer-review

Published

Abolition of prescription charges in Wales: the impact on medicines use in those who used to pay

Hughes, D., Groves, S., Cohen, D., Alam, M. F., Dunstan, F. D., Routledge, P. A., Hughes, D. A. & Myles, S., 1 Dec 2010, In: International Journal of Pharmacy Practice. 18, 6, p. 332-340

Research output: Contribution to journal › Article › peer-review

Published

Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program

Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872

Research output: Contribution to journal › Article › peer-review

Published

The problem of orphan drugs

Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

Research output: Contribution to journal › Article › peer-review

Published

From NCE to NICE: the role of pharmacoeconomics

Hughes, D. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 317-319

Research output: Contribution to journal › Article › peer-review

Published

Generic and therapeutic substitutions in the UK: are they a good thing?

Hughes, D., Duerden, M. G. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 335-341

Research output: Contribution to journal › Article › peer-review

Published

Abolition of prescription copayments in Wales: an observational study on dispensing rates.

Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

Research output: Contribution to journal › Article › peer-review

Published

Is exercise effective in promoting mental well-being in older age? A systematic review.

Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

Research output: Contribution to journal › Article › peer-review

Published

A systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives

Hughes, D., Verhoef, T. I., Redekop, W. K., Darba, J., Geitona, M., Hughes, D. A., Siebert, U., de Boer, A., Maitland-van der Zee, A. H., Barallon, R., Briz, M., Daly, A., Haschke-Becher, E., Kamali, F., Kirchheiner, J., Manolopoulos, V. G., Pirmohamed, M., Rosendaal, F. R., van Schie, R. M. & Wadelius, M., 1 Jul 2010, In: Pharmacogenomics. 11, 7, p. 989-1002

Research output: Contribution to journal › Article › peer-review

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Mar 2010, In: Clinical Pharmacology and Therapeutics. 87, 3, p. 257-261

Research output: Contribution to journal › Article › peer-review

Published

New drugs for old: disinvestment and NICE.

Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572

Research output: Contribution to journal › Article › peer-review

Published

NICE and new: appraising innovation.

Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493

Research output: Contribution to journal › Article › peer-review

Published

Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

Research output: Contribution to conference › Paper

Published

Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

Research output: Contribution to journal › Article › peer-review

Published

Pharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.

Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Oct 2009, In: Clinical Medicine. 9, 5, p. 490-492

Research output: Contribution to journal › Article › peer-review

Published

Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.

Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Sept 2009, In: Value in Health. 12, 6, p. 915-922

Research output: Contribution to journal › Article › peer-review

Published

Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.

Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, M. E., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 26 Aug 2009, In: Malaria Journal. 8, p. 204

Research output: Contribution to journal › Article › peer-review

Published

Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.

Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.

Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Aug 2009, In: Alimentary Pharmacology and Therapeutics. 30, 3, p. 265-274

Research output: Contribution to journal › Article › peer-review

Published

Follow-up of cancer in primary care versus secondary care: systematic review

Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Jul 2009, In: British Journal of General Practice. 59, 564, p. e234-e247

Research output: Contribution to journal › Article › peer-review

Published

Patients' and healthcare professionals' views of cancer follow-up: systematic review

Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259

Research output: Contribution to journal › Article › peer-review

Published

Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

Research output: Contribution to journal › Article › peer-review

Published

Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review

Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723

Research output: Contribution to journal › Article › peer-review

Published

A Framework for Planning and Critiquing Medication Compliance and Persistence Research Using Prospective Study Designs.

Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Zhang, Y., Roy, A., Yu-Isenberg, K., Hughes, D. A. & Nichol, M. B., 1 Feb 2009, In: Clinical Therapeutics. 31, 2, p. 421-435

Research output: Contribution to journal › Article › peer-review

Published

A systematic review and empirical analysis of the relation between dose and duration of drug action.

Hughes, D., Hughes, D. A. & Aronson, J. K., 1 Jan 2009, p. TP40.

Research output: Contribution to conference › Paper

Published

All Wales Medicines Strategy Group Final Appraisal Report - Ambrisentan (Volibris) for pulmonary arterial hypertension.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Anidulafungin (Ecalta) for the treatment of invasive candidiasis in adult non-neutropenic patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Maraviroc (Celsentri) for treatment-experienced adults infected only with CCR5-tropic HIV-1.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Tacrolimus (Advagraf) for the prophylaxis of transplant rejection in adult kidney or liver allograft recipients and the treatment of allograft rejection resistant to treatment with other immunosuppressive medicinal products in adult patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Assessment, Determinants & Economics of Medication Compliance & Persistence Forum.

Hughes, D., Hughes, D. A., Gwadry-Sridhar, F. & Manias, E., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Comparisons between the medication possession ratio (MPR) and gaps measures of medication compliance: are we selling ourselves short by relying on the MPR?

Hughes, D., Nichol, M., Manias, E., Hughes, D. A. & Schabert, V. F., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Drug evaluation and pharmocoeconomics.

Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (ed.), Rees, J. A. (ed.) & Smith, I. (ed.), 1 Jan 2009, Pharmaceutical Practice: 4th Edition.. 2009 ed. Churchill Livingstone, p. 185-198

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published