This thesis is presented as a series of five empirical studies. The first study examined the reproducibility and single-measurement reliability associated with two types of dynamic sensorimotor performance (SMP) assessment task. The SMP assessment tasks were thereafter applied to assess the effects of exercise stress in the form of fatigue, an initial and repeated-bout of exercise induced muscle damage and training on sensorimotor and neuromuscular performance associated with the knee flexor musculature of female athletes. The results from the first study revealed that within-session estimates of both types I and II SMP offered the least level of biological variance or greatest reliability during a single opportunity for assessment. However, such results must be interpreted with caution when used as a clinical outcome measure as the R1 for both types I and II SMP assessment tasks (within-session, within-day, and between-day) do not approach the clinically acceptable reliability coefficient threshold of greater than 0.80 (Currier, 1984). This represents a limited capacity to di scriminate physiological change in types I and II SMP performance, based on a single trial for both within-day and between-day assessments. Therefore, the mean score of 15 and 25 trials is recommended as the basis for estimating sensorimotor performance in order to reduce measurement eITor during types I and II SMP tasks, respectively. The second study examined the effects of four bouts of an acute fatigue protocol ( 4 x 40 seconds of maximal isometric activity in the knee flexor musculature) and acute recovery ( at 1, 3 and 6 minutes following the cessation of exercise) on neuromuscular and sensorimotor perf01mance of the knee flexors in female soccer players. A 20% disruption to peak force was observed following the fatigue intervention alongside a significant alteration to the evoked neuromuscular activation response and the accuracy of force perception. This may have significant implications during a 90 minute soccer game when an even greater potential for a loss of strength and dynamic support around the knee joint may exist. The third and fourth studies investigated the effects of an initial-bout and repeated-bout of exercise induced muscle damage (EIMD) on the physiological, neuromuscular and sensorimotor performance of the knee flexors in female athletes. EIMD was confirmed in both phases of the experiment via several physiological indicators of EIMD and a significant ( 20%) loss of strength in the knee flexors. Therefore, the repeated-bout effect was not witnessed during a second exposure to an eccentric exercise protocol in the knee flexors. Sensorimotor performance was however preserved during conditions of EIMD which suggests a protective role of force regulation during functional disruption to the lower limb. Finally, a functional training intervention was assessed for its effect on sensorimotor and neuromuscular performance of the knee flexors in female athletes both at rest and following a single episode of fatigue. No significant alteration to sensorimotor or neuromuscular performance of the knee flexors was witnessed following the two-week intervention period. This may represent either a limited capacity to discriminate a biologically meaningful level of change in the performance indices, or the fact that sensorimotor performance may not be significantly improved in the knee flexors of the 'healthy' female athlete during the chosen period of exposure to the training stimulus.