Synthetic studies towards analogues of ptilomycalin A

Electronic versions

Documents

  • Spencer Maurice Jones

Abstract

The thesis describes three synthetic approaches to analogues of ptilomycalin A and studies their biological activity. The analogue 181 was prepared by a linear synthetic route and this compound was found to be, as expected, biologically largely inactive. A convergent synthetic approach was applied to the synthesis of the analogues 214, 191 and 192.

Details

Original languageEnglish
Awarding Institution
  • Bangor University
Supervisors/Advisors
  • Paddy Murphy (Supervisor)
Award dateJan 2004