Convergent consequences of parthenogenesis on stick insect genomes
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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Yn: Science Advances, Cyfrol 8, Rhif 8, eabg3842, 23.02.2022.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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T1 - Convergent consequences of parthenogenesis on stick insect genomes
AU - Jaron, Kamil S
AU - Parker, Darren J
AU - Anselmetti, Yoann
AU - Tran Van, Patrick
AU - Bast, Jens
AU - Dumas, Zoé
AU - Figuet, Emeric
AU - François, Clémentine M
AU - Hayward, Keith
AU - Rossier, Victor
AU - Simion, Paul
AU - Robinson-Rechavi, Marc
AU - Galtier, Nicolas
AU - Schwander, Tanja
PY - 2022/2/23
Y1 - 2022/2/23
N2 - The shift from sexual reproduction to parthenogenesis has occurred repeatedly in animals, but how the loss of sex affects genome evolution remains poorly understood. We generated reference genomes for five independently evolved parthenogenetic species in the stick insect genus Timema and their closest sexual relatives. Using these references and population genomic data, we show that parthenogenesis results in an extreme reduction of heterozygosity and often leads to genetically uniform populations. We also find evidence for less effective positive selection in parthenogenetic species, suggesting that sex is ubiquitous in natural populations because it facilitates fast rates of adaptation. Parthenogenetic species did not show increased transposable element (TE) accumulation, likely because there is little TE activity in the genus. By using replicated sexual-parthenogenetic comparisons, our study reveals how the absence of sex affects genome evolution in natural populations, providing empirical support for the negative consequences of parthenogenesis as predicted by theory.
AB - The shift from sexual reproduction to parthenogenesis has occurred repeatedly in animals, but how the loss of sex affects genome evolution remains poorly understood. We generated reference genomes for five independently evolved parthenogenetic species in the stick insect genus Timema and their closest sexual relatives. Using these references and population genomic data, we show that parthenogenesis results in an extreme reduction of heterozygosity and often leads to genetically uniform populations. We also find evidence for less effective positive selection in parthenogenetic species, suggesting that sex is ubiquitous in natural populations because it facilitates fast rates of adaptation. Parthenogenetic species did not show increased transposable element (TE) accumulation, likely because there is little TE activity in the genus. By using replicated sexual-parthenogenetic comparisons, our study reveals how the absence of sex affects genome evolution in natural populations, providing empirical support for the negative consequences of parthenogenesis as predicted by theory.
U2 - 10.1126/sciadv.abg3842
DO - 10.1126/sciadv.abg3842
M3 - Article
C2 - 35196080
VL - 8
JO - Science Advances
JF - Science Advances
SN - 2375-2548
IS - 8
M1 - eabg3842
ER -