Porth Ymchwil

Discovery of lost diversity of paternal horse lineages using ancient DNA

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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Discovery of lost diversity of paternal horse lineages using ancient DNA. / Lippold, S.; Knapp, M.; Kuznetsova, T. et al.
Yn: Nature Communications, Cyfrol 2, 23.08.2011, t. 450.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

HarvardHarvard

Lippold, S, Knapp, M, Kuznetsova, T, Leonard, JA, Benecke, N, Ludwig, A, Rasmussen, M, Cooper, A, Weinstock, J, Willerslev, E, Shapiro, B & Hofreiter, M 2011, 'Discovery of lost diversity of paternal horse lineages using ancient DNA', Nature Communications, cyfrol. 2, tt. 450. https://doi.org/10.1038/ncomms1447

APA

Lippold, S., Knapp, M., Kuznetsova, T., Leonard, J. A., Benecke, N., Ludwig, A., Rasmussen, M., Cooper, A., Weinstock, J., Willerslev, E., Shapiro, B., & Hofreiter, M. (2011). Discovery of lost diversity of paternal horse lineages using ancient DNA. Nature Communications, 2, 450. https://doi.org/10.1038/ncomms1447

CBE

Lippold S, Knapp M, Kuznetsova T, Leonard JA, Benecke N, Ludwig A, Rasmussen M, Cooper A, Weinstock J, Willerslev E, et al. 2011. Discovery of lost diversity of paternal horse lineages using ancient DNA. Nature Communications. 2:450. https://doi.org/10.1038/ncomms1447

MLA

Lippold, S. et al. "Discovery of lost diversity of paternal horse lineages using ancient DNA". Nature Communications. 2011, 2. 450. https://doi.org/10.1038/ncomms1447

VancouverVancouver

Lippold S, Knapp M, Kuznetsova T, Leonard JA, Benecke N, Ludwig A et al. Discovery of lost diversity of paternal horse lineages using ancient DNA. Nature Communications. 2011 Awst 23;2:450. doi: 10.1038/ncomms1447

Author

Lippold, S. ; Knapp, M. ; Kuznetsova, T. et al. / Discovery of lost diversity of paternal horse lineages using ancient DNA. Yn: Nature Communications. 2011 ; Cyfrol 2. tt. 450.

RIS

TY - JOUR

T1 - Discovery of lost diversity of paternal horse lineages using ancient DNA

AU - Lippold, S.

AU - Knapp, M.

AU - Kuznetsova, T.

AU - Leonard, J.A.

AU - Benecke, N.

AU - Ludwig, A.

AU - Rasmussen, M.

AU - Cooper, A.

AU - Weinstock, J.

AU - Willerslev, E.

AU - Shapiro, B.

AU - Hofreiter, M.

PY - 2011/8/23

Y1 - 2011/8/23

N2 - Modern domestic horses display abundant genetic diversity within female-inherited mitochondrial DNA, but practically no sequence diversity on the male-inherited Y chromosome. Several hypotheses have been proposed to explain this discrepancy, but can only be tested through knowledge of the diversity in both the ancestral (pre-domestication) maternal and paternal lineages. As wild horses are practically extinct, ancient DNA studies offer the only means to assess this ancestral diversity. Here we show considerable ancestral diversity in ancient male horses by sequencing 4 kb of Y chromosomal DNA from eight ancient wild horses and one 2,800-year-old domesticated horse. Both ancient and modern domestic horses form a separate branch from the ancient wild horses, with the Przewalski horse at its base. Our methodology establishes the feasibility of re-sequencing long ancient nuclear DNA fragments and demonstrates the power of ancient Y chromosome DNA sequence data to provide insights into the evolutionary history of populations.

AB - Modern domestic horses display abundant genetic diversity within female-inherited mitochondrial DNA, but practically no sequence diversity on the male-inherited Y chromosome. Several hypotheses have been proposed to explain this discrepancy, but can only be tested through knowledge of the diversity in both the ancestral (pre-domestication) maternal and paternal lineages. As wild horses are practically extinct, ancient DNA studies offer the only means to assess this ancestral diversity. Here we show considerable ancestral diversity in ancient male horses by sequencing 4 kb of Y chromosomal DNA from eight ancient wild horses and one 2,800-year-old domesticated horse. Both ancient and modern domestic horses form a separate branch from the ancient wild horses, with the Przewalski horse at its base. Our methodology establishes the feasibility of re-sequencing long ancient nuclear DNA fragments and demonstrates the power of ancient Y chromosome DNA sequence data to provide insights into the evolutionary history of populations.

U2 - 10.1038/ncomms1447

DO - 10.1038/ncomms1447

M3 - Article

VL - 2

SP - 450

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

ER -