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Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. / Gillespie, David; Knapper, Carys; Hughes, Dyfrig et al.
Yn: Sexually transmitted infections, Cyfrol 97, Rhif 2, 054598, 17.02.2021, t. 85-87.

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

HarvardHarvard

Gillespie, D, Knapper, C, Hughes, D, Couzen, Z, Wood, F, de Bruin, M, Ma, R, Jones, AT, Williams, A & Hood, K 2021, 'Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales', Sexually transmitted infections, cyfrol. 97, rhif 2, 054598, tt. 85-87. https://doi.org/10.1136/sextrans-2020-054598

APA

Gillespie, D., Knapper, C., Hughes, D., Couzen, Z., Wood, F., de Bruin, M., Ma, R., Jones, A. T., Williams, A., & Hood, K. (2021). Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. Sexually transmitted infections, 97(2), 85-87. Erthygl 054598. https://doi.org/10.1136/sextrans-2020-054598

CBE

Gillespie D, Knapper C, Hughes D, Couzen Z, Wood F, de Bruin M, Ma R, Jones AT, Williams A, Hood K. 2021. Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. Sexually transmitted infections. 97(2):85-87. https://doi.org/10.1136/sextrans-2020-054598

MLA

VancouverVancouver

Gillespie D, Knapper C, Hughes D, Couzen Z, Wood F, de Bruin M et al. Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. Sexually transmitted infections. 2021 Chw 17;97(2):85-87. 054598. Epub 2020 Medi 23. doi: 10.1136/sextrans-2020-054598

Author

Gillespie, David ; Knapper, Carys ; Hughes, Dyfrig et al. / Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. Yn: Sexually transmitted infections. 2021 ; Cyfrol 97, Rhif 2. tt. 85-87.

RIS

TY - JOUR

T1 - Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales

AU - Gillespie, David

AU - Knapper, Carys

AU - Hughes, Dyfrig

AU - Couzen, Zoë

AU - Wood, Fiona

AU - de Bruin, Marijn

AU - Ma, Richard

AU - Jones, Adam T.

AU - Williams, Adam

AU - Hood, Kerenza

N1 - © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2021/2/17

Y1 - 2021/2/17

N2 - OBJECTIVES: To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales.METHODS: Data were obtained from an ecological momentary assessment study of PrEP use and sexual behaviour. Participants were individuals accessing PrEP through the National Health Service (NHS) sexual health clinics across four health boards in Wales. Weekly data documenting condomless sex in the preceding week were analysed between 03/02/2020 and 10/05/2020. The introduction of social distancing measures and changes to sexual health clinics in Wales occurred on the week starting 16/03/2020. Two-level logistic regression models were fitted to condomless sex (yes/no) over time, included an indicator for the week starting 16/03/2020, and were extended to explore differential associations by relationship status and sexual health clinic.RESULTS: Data were available from 56 participants and included 697 person-weeks (89% of the maximum number that could have been obtained). On average, 42% of participants reported condomless sex in the period prior to the introduction of social distancing measures and 20% reported condomless sex after (OR=0.16, 95% CI 0.07 to 0.37, p<0.001). There was some evidence to suggest that this association was moderated by relationship status (OR for single participants=0.09, 95% CI 0.06 to 0.23; OR for not single participants=0.46, 95% CI 0.16 to 1.25).CONCLUSIONS: The introduction of social distancing measures and changes to PrEP services across Wales was associated with a marked reduction in reported instances of condomless sexual intercourse among respondents, with a larger reduction in those who were single compared with those who were not. The long-term impact of COVID-19 and associated control measures on this population's physical and mental health and well-being requires close examination.

AB - OBJECTIVES: To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales.METHODS: Data were obtained from an ecological momentary assessment study of PrEP use and sexual behaviour. Participants were individuals accessing PrEP through the National Health Service (NHS) sexual health clinics across four health boards in Wales. Weekly data documenting condomless sex in the preceding week were analysed between 03/02/2020 and 10/05/2020. The introduction of social distancing measures and changes to sexual health clinics in Wales occurred on the week starting 16/03/2020. Two-level logistic regression models were fitted to condomless sex (yes/no) over time, included an indicator for the week starting 16/03/2020, and were extended to explore differential associations by relationship status and sexual health clinic.RESULTS: Data were available from 56 participants and included 697 person-weeks (89% of the maximum number that could have been obtained). On average, 42% of participants reported condomless sex in the period prior to the introduction of social distancing measures and 20% reported condomless sex after (OR=0.16, 95% CI 0.07 to 0.37, p<0.001). There was some evidence to suggest that this association was moderated by relationship status (OR for single participants=0.09, 95% CI 0.06 to 0.23; OR for not single participants=0.46, 95% CI 0.16 to 1.25).CONCLUSIONS: The introduction of social distancing measures and changes to PrEP services across Wales was associated with a marked reduction in reported instances of condomless sexual intercourse among respondents, with a larger reduction in those who were single compared with those who were not. The long-term impact of COVID-19 and associated control measures on this population's physical and mental health and well-being requires close examination.

KW - Adult

KW - COVID-19

KW - Communicable Disease Control

KW - Condoms/statistics & numerical data

KW - Ecological Momentary Assessment

KW - HIV Infections/prevention & control

KW - Humans

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Physical Distancing

KW - Pre-Exposure Prophylaxis

KW - SARS-CoV-2

KW - Sexual Behavior/statistics & numerical data

KW - Unsafe Sex/statistics & numerical data

KW - Wales

U2 - 10.1136/sextrans-2020-054598

DO - 10.1136/sextrans-2020-054598

M3 - Article

C2 - 32967930

VL - 97

SP - 85

EP - 87

JO - Sexually transmitted infections

JF - Sexually transmitted infections

SN - 1368-4973

IS - 2

M1 - 054598

ER -