TY - JOUR

T1 - Effect of low- and high-carbohydrate diets on the plasma glutamine and circulating leukocyte responses to exercise

AU - Gleeson, M.

AU - Blannin, Andrew K.

AU - Walsh, Neil

AU - Bishop, Nicolette C.

AU - Clark, Anya M.

PY - 1998/3

Y1 - 1998/3

N2 - We examined the effects of a low-carbohydrate (CHO) diet on the plasma glutamine and circulating leukocyte responses to prolonged strenuous exercise. Twelve untrained male subjects cycled for 60 min at 70% of maximal oxygen uptake on two separate occasions, 3 days apart. All subjects performed the first exercise task after a normal diet; they completed the second exercise task after 3 days on either a high-CHO diet (75 +/- 8% CHO, n = 6) or a low-CHO diet (7 +/- 4% CHO, n = 6). The low-CHO diet was associated with a larger rise in plasma cortisol during exercise, a greater fall in the plasma glutamine concentration during recovery, and a larger neutrophilia during the postexercise period. Exercise on the high-CHO diet did not affect levels of plasma glutamine and circulating leukocytes. We conclude that CHO availability can influence the plasma glutamine and circulating leukocyte responses during recovery from intense prolonged exercise.

AB - We examined the effects of a low-carbohydrate (CHO) diet on the plasma glutamine and circulating leukocyte responses to prolonged strenuous exercise. Twelve untrained male subjects cycled for 60 min at 70% of maximal oxygen uptake on two separate occasions, 3 days apart. All subjects performed the first exercise task after a normal diet; they completed the second exercise task after 3 days on either a high-CHO diet (75 +/- 8% CHO, n = 6) or a low-CHO diet (7 +/- 4% CHO, n = 6). The low-CHO diet was associated with a larger rise in plasma cortisol during exercise, a greater fall in the plasma glutamine concentration during recovery, and a larger neutrophilia during the postexercise period. Exercise on the high-CHO diet did not affect levels of plasma glutamine and circulating leukocytes. We conclude that CHO availability can influence the plasma glutamine and circulating leukocyte responses during recovery from intense prolonged exercise.

KW - 3-Hydroxybutyric Acid

KW - Adult

KW - Cohort Studies

KW - Dietary Carbohydrates

KW - Exercise

KW - Food, Formulated

KW - Glutamine

KW - Humans

KW - Hydrocortisone

KW - Hydroxybutyrates

KW - Lactic Acid

KW - Leukocyte Count

KW - Leukocytes

KW - Lymphocyte Count

KW - Male

KW - Neutrophils

KW - Clinical Trial

KW - Comparative Study

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.1123/ijsn.8.1.49

DO - 10.1123/ijsn.8.1.49

M3 - Article

C2 - 9534081

VL - 8

SP - 49

EP - 59

JO - International journal of sport nutrition

JF - International journal of sport nutrition

SN - 1050-1606

IS - 1

ER -