Engineering biology applications for environmental solutions: potential and challenges

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  • David J. Lea-Smith
    University of East Anglia
  • Francis Hassard
    Cranfield University, Cranfield, UK
  • Frederic Coulon
    Cranfield University, Cranfield, UK
  • Natalie Partridge
    GitLife Biotech Ltd, Newcastle Upon Tyne, UK
  • Louise Horsfall
    University of Edinburgh
  • Kyle D. J. Parker
    University of Edinburgh
  • Robert D. J. Smith
    University of Edinburgh
  • Ronan R. McCarty
    Brunel University
  • Boyd McKew
    University of Essex
  • Tony Guttierrez
    Heriot-Watt University, Edinburgh
  • Vinod Kumar
    Cranfield University, Cranfield, UK
  • Gabriella Dotro
    Cranfield University, Cranfield, UK
  • Zhugen Yang
    Cranfield University, Cranfield, UK
  • Peter Golyshin
  • Natalio Krasnogor
    GitLife Biotech Ltd, Newcastle Upon Tyne, UK
Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.
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CyfnodolynNature Communications
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Dyddiad ar-lein cynnar14 Ebr 2025
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