TY - JOUR

T1 - Impaired visuospatial transformation but intact sequence processing in Parkinson disease

AU - Leek, C.

AU - Leek, E.C.

AU - Kerai, J.H.

AU - Johnston, S.J.

AU - Hindle, J.V.

AU - Bracewell, R.M.

PY - 2014/9/1

Y1 - 2014/9/1

N2 - We examined whether visuospatial deficits in Parkinson disease (PD) can be explained by a domain-general, The authors examined whether visuospatial deficits in Parkinson's disease (PD) can be explained by a domain–general, nonspatial impairment in the sequencing or serial chaining of mental operations. They argue that visuospatial deficits in PD result from impairments to spatial transformation routines involved in the computation of mappings between spatial locations. These routines are mediated by dopaminergic pathways linking the basal ganglia, prefrontal cortex, supplementary motor area, and parietal cortex.

AB - We examined whether visuospatial deficits in Parkinson disease (PD) can be explained by a domain-general, The authors examined whether visuospatial deficits in Parkinson's disease (PD) can be explained by a domain–general, nonspatial impairment in the sequencing or serial chaining of mental operations. They argue that visuospatial deficits in PD result from impairments to spatial transformation routines involved in the computation of mappings between spatial locations. These routines are mediated by dopaminergic pathways linking the basal ganglia, prefrontal cortex, supplementary motor area, and parietal cortex.

U2 - 10.1097/WNN.0000000000000032

DO - 10.1097/WNN.0000000000000032

M3 - Article

VL - 27

SP - 130

EP - 138

JO - Cognitive and Behavioral Neurology

JF - Cognitive and Behavioral Neurology

SN - 1543-3633

IS - 3

ER -