Individualised exercise improves endothelial function in patients with rheumatoid arthritis

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

Fersiynau electronig

Dangosydd eitem ddigidol (DOI)

  • A.A. Sandoo
  • G. Kitas
  • G.S. Metsios
  • A. Stavropoulos-Kalinoglou
  • J. Veldhuijzen van Zanten
  • P. Nightingale
  • A. Sandoo
  • T. Dimitroulas
  • G.D. Kitas
  • Y. Koutedakis
We investigated the effects of individualised combined resistance and aerobic exercise on microvascular and macrovascular function in rheumatoid arthritis (RA) patients. Forty age-matched, gender-matched and body mass index (BMI)-matched patients were allocated to either an exercise group, receiving a 6 months tailored aerobic and resistance exercise intervention, or controls receiving only information about the benefits of exercise. Participants were assessed for microvascular (acetylcholine (Ach) and sodium nitroprusside (SNP)) and macrovascular (flow-mediated dilatation (FMD) and glyceryl trinitrate (GTN)) endothelial function, maximal oxygen uptake, disease activity and severity (C-reactive protein (CRP), disease activity score 28 and health assessment questionnaire). Data were collected at baseline, 3 months and at the end of the intervention (6 months). At baseline, demographic, anthropometric, disease-related characteristics and endothelial function parameters were similar between the exercise and control groups (p>0.05). Repeated measures analysis of variance revealed a significant improvement in endothelial function parameters at 3 (GTN: p
Iaith wreiddiolSaesneg
Tudalennau (o-i)748-751
CyfnodolynAnnals of Rheumatic Diseases
Cyfrol73
Rhif y cyfnodolyn4
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 31 Gorff 2013
Gweld graff cysylltiadau