Localized 1H NMR spectroscopy of rat spinal cord in vivo

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

Fersiynau electronig

Dangosydd eitem ddigidol (DOI)

  • F O Zelaya
    University of Queensland
  • J B Chalk
  • P Mullins
    University of Queensland
  • I M Brereton
  • D M Doddrell

A movable, actively decoupled surface coil has been employed to obtain a localized 1H NMR spectrum from the lumbosacral spinal cord of a live Lewis rat. A volume selective 'VOSY' normally spelled out as 'volume selective spectroscopy' spectroscopy pulse sequence that incorporates 'phase ramped' selective RF pulses, has been used to minimize random phase jitter in the NMR signal as a result of the large frequency shifts required to locate the voxel in the center of the cord while using intense gradient pulses. Spectra from 13-microliters voxels in healthy rats and in rats inoculated with guinea pig spinal cord and complete Freund's adjuvant, resulting in experimental autoimmune encephalomyelitis, are shown.

Allweddeiriau

Iaith wreiddiolSaesneg
Tudalennau (o-i)443-8
Nifer y tudalennau6
CyfnodolynMagnetic Resonance in Medicine
Cyfrol35
Rhif y cyfnodolyn4
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - Ebr 1996
Cyhoeddwyd yn allanolIe
Gweld graff cysylltiadau