TY - JOUR

T1 - Obsessive Compulsive Treatment Efficacy Trial (OCTET) comparing the clinical and cost effectiveness of self-managed therapies: study protocol for a randomised controlled trial

AU - Gellatly, Judith

AU - Bower, Peter

AU - McMillan, Dean

AU - Roberts, Christopher

AU - Byford, Sarah

AU - Bee, Penny

AU - Gilbody, Simon

AU - Arundel, Catherine Ellen

AU - Hardy, Gillian

AU - Barkham, Michael

AU - Reynolds, Shirley

AU - Gega, Lina

AU - Mottram, Patricia

AU - Lidbetter, Nicola

AU - Pedley, Rebecca

AU - Peckham, Emily Jane

AU - Connell, Janice

AU - Molle, Jo

AU - O'Leary, Neil

AU - Lovell, Karina

PY - 2014/7/10

Y1 - 2014/7/10

N2 - BACKGROUND: UK National Institute of Health and Clinical Excellence guidelines for obsessive compulsive disorder (OCD) specify recommendations for the treatment and management of OCD using a stepped care approach. Steps three to six of this model recommend treatment options for people with OCD that range from low-intensity guided self-help (GSH) to more intensive psychological and pharmacological interventions. Cognitive behavioural therapy (CBT), including exposure and response prevention, is the recommended psychological treatment. However, whilst there is some preliminary evidence that self-managed therapy packages for OCD can be effective, a more robust evidence base of their clinical and cost effectiveness and acceptability is required.METHODS/DESIGN: Our proposed study will test two different self-help treatments for OCD: 1) computerised CBT (cCBT) using OCFighter, an internet-delivered OCD treatment package; and 2) GSH using a book. Both treatments will be accompanied by email or telephone support from a mental health professional. We will evaluate the effectiveness, cost and patient and health professional acceptability of the treatments.DISCUSSION: This study will provide more robust evidence of efficacy, cost effectiveness and acceptability of self-help treatments for OCD. If cCBT and/or GSH prove effective, it will provide additional, more accessible treatment options for people with OCD.TRIAL REGISTRATION: Current Controlled Trials: ISRCTN73535163. Date of registration: 5 April 2011.

AB - BACKGROUND: UK National Institute of Health and Clinical Excellence guidelines for obsessive compulsive disorder (OCD) specify recommendations for the treatment and management of OCD using a stepped care approach. Steps three to six of this model recommend treatment options for people with OCD that range from low-intensity guided self-help (GSH) to more intensive psychological and pharmacological interventions. Cognitive behavioural therapy (CBT), including exposure and response prevention, is the recommended psychological treatment. However, whilst there is some preliminary evidence that self-managed therapy packages for OCD can be effective, a more robust evidence base of their clinical and cost effectiveness and acceptability is required.METHODS/DESIGN: Our proposed study will test two different self-help treatments for OCD: 1) computerised CBT (cCBT) using OCFighter, an internet-delivered OCD treatment package; and 2) GSH using a book. Both treatments will be accompanied by email or telephone support from a mental health professional. We will evaluate the effectiveness, cost and patient and health professional acceptability of the treatments.DISCUSSION: This study will provide more robust evidence of efficacy, cost effectiveness and acceptability of self-help treatments for OCD. If cCBT and/or GSH prove effective, it will provide additional, more accessible treatment options for people with OCD.TRIAL REGISTRATION: Current Controlled Trials: ISRCTN73535163. Date of registration: 5 April 2011.

U2 - 10.1186/1745-6215-15-278

DO - 10.1186/1745-6215-15-278

M3 - Article

VL - 15

SP - 278

JO - Trials

JF - Trials

SN - 1745-6215

ER -