TY - JOUR

T1 - Prolonged QTc interval predicts all-cause mortality in patients with rheumatoid arthritis: an association driven by high inflammatory burden

AU - Sandoo, A.A.

AU - Kitas, G.

AU - Panoulas, V.F.

AU - Toms, T.E.

AU - Douglas, K.M.

AU - Sandoo, A.

AU - Metsios, G.S.

AU - Stavropoulos-Kalinoglou, A.

AU - Kitas, G.D.

PY - 2013/10/3

Y1 - 2013/10/3

N2 - RA associates with an increased rate of sudden cardiac death (SCD). A prolonged QTc interval has been associated with arrhythmogenic and SCD in patients with long QT syndrome. Despite the previously reported contemporary association of CRP with SCD, thus far no studies have examined the association of QTc with mortality in RA, a condition characterized by high inflammatory burden. The aim of this study was to examine the role of electrocardiography (QT corrected interval) in predicting all-cause mortality in patients with RA who have an increased rate of SCD and a high inflammatory burden.

AB - RA associates with an increased rate of sudden cardiac death (SCD). A prolonged QTc interval has been associated with arrhythmogenic and SCD in patients with long QT syndrome. Despite the previously reported contemporary association of CRP with SCD, thus far no studies have examined the association of QTc with mortality in RA, a condition characterized by high inflammatory burden. The aim of this study was to examine the role of electrocardiography (QT corrected interval) in predicting all-cause mortality in patients with RA who have an increased rate of SCD and a high inflammatory burden.

U2 - 10.1093/rheumatology/ket338

DO - 10.1093/rheumatology/ket338

M3 - Article

SP - 131

EP - 137

JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - 1

ER -