TY - JOUR

T1 - Symptoms, ultrasound imaging and biochemical markers alone or in combination for the diagnosis of ovarian cancer in women with symptoms suspicious of ovarian cancer

AU - Rai, N.

AU - Campaneria, R.

AU - Snell, K.

AU - Mallett, S.

AU - Bayliss, S.E.

AU - Neal, R.D.

AU - Balogun, M.

AU - Kehoe, S.

AU - Deeks, J.K.

AU - Sundar, S.

AU - Davenport, C.

PY - 2015/12/7

Y1 - 2015/12/7

N2 - This is the protocol for a review and there is no abstract. The objectives are as follows: To establish the accuracy of symptoms, ultrasound and biomarkers alone or in combination for the diagnosis of ovarian cancer in pre- and postmenopausal women. To compare the accuracy of different tests or test combinations. We will investigate the following sources of heterogeneity: Population Clinical setting (generalist/primary care/community/family practice) versus specialist setting (cancer unit/cancer centre/gynaecological oncology) Menopausal status Index tests Test positivity threshold Experience of the ultrasound test operator (general sonographers versus specialist interest) Target condition Histological subtype Study quality Case-control versus other study designs Study quality: for study participants not receiving surgery initially following a negative index test result: 12 months follow-up versus less than 12 months follow-up

AB - This is the protocol for a review and there is no abstract. The objectives are as follows: To establish the accuracy of symptoms, ultrasound and biomarkers alone or in combination for the diagnosis of ovarian cancer in pre- and postmenopausal women. To compare the accuracy of different tests or test combinations. We will investigate the following sources of heterogeneity: Population Clinical setting (generalist/primary care/community/family practice) versus specialist setting (cancer unit/cancer centre/gynaecological oncology) Menopausal status Index tests Test positivity threshold Experience of the ultrasound test operator (general sonographers versus specialist interest) Target condition Histological subtype Study quality Case-control versus other study designs Study quality: for study participants not receiving surgery initially following a negative index test result: 12 months follow-up versus less than 12 months follow-up

U2 - 10.1002/14651858.CD011964

DO - 10.1002/14651858.CD011964

M3 - Article

VL - 2015

JO - Cochrane Library

JF - Cochrane Library

SN - 1465-1858

IS - 12

M1 - CD011964

ER -