Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

StandardStandard

Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria. / Taher, Salam; Al-Dulayymi, Juma'a R.; Tima, H. Griesse et al.
Yn: Tetrahedron, Cyfrol 72, Rhif 27-28, 07.07.2016, t. 3863-3876.

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

HarvardHarvard

Taher, S, Al-Dulayymi, JR, Tima, HG, Ali, HM, Romano, M & Baird, M 2016, 'Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria', Tetrahedron, cyfrol. 72, rhif 27-28, tt. 3863-3876. https://doi.org/10.1016/j.tet.2016.05.004

APA

Taher, S., Al-Dulayymi, J. R., Tima, H. G., Ali, H. M., Romano, M., & Baird, M. (2016). Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria. Tetrahedron, 72(27-28), 3863-3876. https://doi.org/10.1016/j.tet.2016.05.004

CBE

MLA

VancouverVancouver

Taher S, Al-Dulayymi JR, Tima HG, Ali HM, Romano M, Baird M. Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria. Tetrahedron. 2016 Gor 7;72(27-28):3863-3876. Epub 2016 Mai 6. doi: 10.1016/j.tet.2016.05.004

Author

Taher, Salam ; Al-Dulayymi, Juma'a R. ; Tima, H. Griesse et al. / Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria. Yn: Tetrahedron. 2016 ; Cyfrol 72, Rhif 27-28. tt. 3863-3876.

RIS

TY - JOUR

T1 - Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria

AU - Taher, Salam

AU - Al-Dulayymi, Juma'a R.

AU - Tima, H. Griesse

AU - Ali, Hanan M.

AU - Romano, Marta

AU - Baird, Mark

PY - 2016/7/7

Y1 - 2016/7/7

N2 - The synthesis of mycobacterial mycolic acid related wax esters and of their trehalose di- and mono-esters is described. The trehalose dimycolates (TDMs) synthesised activated bone marrow derived dendritic cells (BMDCs) in vitro more strongly than trehalose dibehenate or the trehalose monomycolates (TMMs). The inflammatory effects were similar to those of TDM from either a synthetic keto- or methoxy-mycolic acid, but somewhat stronger than those of a TDM from an α-mycolic acid. In vivo, the effects of one wax ester TDM were similar to those of the methoxy-MA and α-mycolic acid TDMs and trehalose dibehenate.

AB - The synthesis of mycobacterial mycolic acid related wax esters and of their trehalose di- and mono-esters is described. The trehalose dimycolates (TDMs) synthesised activated bone marrow derived dendritic cells (BMDCs) in vitro more strongly than trehalose dibehenate or the trehalose monomycolates (TMMs). The inflammatory effects were similar to those of TDM from either a synthetic keto- or methoxy-mycolic acid, but somewhat stronger than those of a TDM from an α-mycolic acid. In vivo, the effects of one wax ester TDM were similar to those of the methoxy-MA and α-mycolic acid TDMs and trehalose dibehenate.

U2 - 10.1016/j.tet.2016.05.004

DO - 10.1016/j.tet.2016.05.004

M3 - Article

VL - 72

SP - 3863

EP - 3876

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 27-28

ER -