UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life: A Study Protocol

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

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UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life: A Study Protocol. / Rowen, Donna; Mukuria, Clara; Bray, Nathan et al.
Yn: Value in Health, Cyfrol 26, Rhif 11, 11.2023, t. 1625-1635.

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

HarvardHarvard

Rowen, D, Mukuria, C, Bray, N, Carlton, J, Cooper, S, Longworth, L, Meads, D, O'Neill, C & Yang, Y 2023, 'UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life: A Study Protocol', Value in Health, cyfrol. 26, rhif 11, tt. 1625-1635. https://doi.org/10.1016/j.jval.2023.08.005

APA

Rowen, D., Mukuria, C., Bray, N., Carlton, J., Cooper, S., Longworth, L., Meads, D., O'Neill, C., & Yang, Y. (2023). UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life: A Study Protocol. Value in Health, 26(11), 1625-1635. https://doi.org/10.1016/j.jval.2023.08.005

CBE

Rowen D, Mukuria C, Bray N, Carlton J, Cooper S, Longworth L, Meads D, O'Neill C, Yang Y. 2023. UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life: A Study Protocol. Value in Health. 26(11):1625-1635. https://doi.org/10.1016/j.jval.2023.08.005

MLA

VancouverVancouver

Rowen D, Mukuria C, Bray N, Carlton J, Cooper S, Longworth L et al. UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life: A Study Protocol. Value in Health. 2023 Tach;26(11):1625-1635. Epub 2023 Medi 16. doi: 10.1016/j.jval.2023.08.005

Author

Rowen, Donna ; Mukuria, Clara ; Bray, Nathan et al. / UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life : A Study Protocol. Yn: Value in Health. 2023 ; Cyfrol 26, Rhif 11. tt. 1625-1635.

RIS

TY - JOUR

T1 - UK Valuation of EQ-5D-5L, a Generic Measure of Health-Related Quality of Life

T2 - A Study Protocol

AU - Rowen, Donna

AU - Mukuria, Clara

AU - Bray, Nathan

AU - Carlton, Jill

AU - Cooper, Sophie

AU - Longworth, Louise

AU - Meads, David

AU - O'Neill, Ciaran

AU - Yang, Yaling

N1 - Copyright © 2023. Published by Elsevier Inc.

PY - 2023/11

Y1 - 2023/11

N2 - OBJECTIVES: A high-quality and widely accepted UK EQ-5D-5L value set is urgently required to enable the latest version of EQ-5D scored using recent UK public preferences to inform policy including health technology assessments submitted to the National Institute for Health and Care Excellence. This article outlines the study protocol for the generation of a new EQ-5D-5L UK value set.METHODS: Twelve hundred interviews will be undertaken using the composite time trade-off elicitation technique for 102 health states (86 from the international EQ-5D-5L valuation protocol, plus 16 with best predictive performance in an extended design used in the Native American EQ-5D-5L valuation). The sample will be UK adults (age ≥18 years) proportionately representative across England, Wales, Scotland, and Northern Ireland, representative for age, sex, ethnicity, and socioeconomic group, with inclusion of participants with/without health problems. Participants will choose to be interviewed via videoconference (by Zoom) or in-person in a central venue. Data quality will be rigorously assessed.RESULTS: The value set will be generated using tobit random effects and heteroscedastic tobit models (with censoring at -1) using all data, excluding time trade-off values highlighted by participants as ones they would reconsider and data from interviewers failing protocol compliance. Quality and acceptance will be achieved by public involvement, regular Steering Group meetings, independent assessment of data quality at 4 time points, and final endorsement of data and analyses.CONCLUSION: This study will produce a UK value set for the EQ-5D-5L for use in prospective and retrospective data sets containing EQ-5D-5L data.

AB - OBJECTIVES: A high-quality and widely accepted UK EQ-5D-5L value set is urgently required to enable the latest version of EQ-5D scored using recent UK public preferences to inform policy including health technology assessments submitted to the National Institute for Health and Care Excellence. This article outlines the study protocol for the generation of a new EQ-5D-5L UK value set.METHODS: Twelve hundred interviews will be undertaken using the composite time trade-off elicitation technique for 102 health states (86 from the international EQ-5D-5L valuation protocol, plus 16 with best predictive performance in an extended design used in the Native American EQ-5D-5L valuation). The sample will be UK adults (age ≥18 years) proportionately representative across England, Wales, Scotland, and Northern Ireland, representative for age, sex, ethnicity, and socioeconomic group, with inclusion of participants with/without health problems. Participants will choose to be interviewed via videoconference (by Zoom) or in-person in a central venue. Data quality will be rigorously assessed.RESULTS: The value set will be generated using tobit random effects and heteroscedastic tobit models (with censoring at -1) using all data, excluding time trade-off values highlighted by participants as ones they would reconsider and data from interviewers failing protocol compliance. Quality and acceptance will be achieved by public involvement, regular Steering Group meetings, independent assessment of data quality at 4 time points, and final endorsement of data and analyses.CONCLUSION: This study will produce a UK value set for the EQ-5D-5L for use in prospective and retrospective data sets containing EQ-5D-5L data.

KW - Adult

KW - Humans

KW - Adolescent

KW - Quality of Life

KW - Health Status

KW - Prospective Studies

KW - Retrospective Studies

KW - Surveys and Questionnaires

KW - England

U2 - 10.1016/j.jval.2023.08.005

DO - 10.1016/j.jval.2023.08.005

M3 - Article

C2 - 37722593

VL - 26

SP - 1625

EP - 1635

JO - Value in Health

JF - Value in Health

SN - 1524-4733

IS - 11

ER -