[Pre-Aug 2018] North Wales Centre for Primary Care Research

  1. Published

    Polymorphisms in the Tropomyosin TPM1 Short Isoform Promoter Alter Gene Expression and Are Associated With Increased Risk of Metabolic Syndrome

    Savill, S. A., Leitch, H. F., Daly, A. K., Harvey, J. N. & Thomas, T. H., 1 Apr 2010, In: American Journal of Hypertension. 23, 4, p. 399-404

    Research output: Contribution to journalArticlepeer-review

  2. Published

    Diabetes, metformin and lactic acidosis

    Scale, T. & Harvey, J. N., 1 Feb 2011, In: Clinical Endocrinology. 74, 2, p. 191-196

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Alpha adrenoceptor agonist-induced microcirculatory oscillations are reduced in diabetic neuropathy.

    Schmiedel, O., Nurmikko, T. J., Schroeter, M. L., Whitaker, R. & Harvey, J. N., 1 Aug 2008, In: Microvascular Research. 76, 2, p. 124-131

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Quantifying the risk of multiple myeloma from symptoms reported by primary care patients: a large case-control study using electronic records

    Shepard, E. A., Neal, R. D., Rose, P., Walter, F. M. & Hamilton, W. T., 1 Feb 2015, In: British Journal of General Practice. 65, 631, p. E106-E113

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Clinical features of bladder cancer in primary care

    Shephard, E., Stapley, S., Neal, R. D., Rose, P., Walter, F. & Hamilton, W. T., 1 Sept 2012, In: British Journal of General Practice. 62, 602, p. e598-604

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Quantifying the risk of Hodgkin lymphoma in symptomatic primary care patients aged ≥40 years: a case–control study using electronic records

    Shephard, E. A., Neal, R. D., Rose, P. W., Walter, F. M. & Hamilton, W. T., 1 May 2015, In: British Journal of General Practice. p. e289-e294

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Symptoms of adult chronic and acute Leukaemia before diagnosis: Large primary care case-control studies using electronic records

    Shephard, E. A., Neal, R. D., Rose, P. W., Walter, F. M. & Hamilton, W. T., 1 Mar 2016, In: British Journal of General Practice. 66, 644, p. e171-e181

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Quantifying the risk of non-Hodgkin lymphoma in symptomatic primary care patients aged ≥40 years: a large case–control study using electronic records

    Shephard, E. A., Neal, R. D., Rose, P. W., Walter, F. M. & Hamilton, W. T., 1 May 2015, In: British Journal of General Practice. 65, 634, p. e281-e288

    Research output: Contribution to journalArticlepeer-review

  9. Published

    ‘Carrying on the way we are, is becoming shambolic’ – An interview study with prostate cancer specialists about their usual practice of follow-up

    Stanciu, M. A., Bulger, J. K., Hiscock, J., Neal, R. D., Stanciu, A., Makin, M. & Wilkinson, C., 2 Jun 2015, In: Journal of Clinical Urology. 8, 4, p. 240-245

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Development of an intervention to expedite cancer diagnosis through primary care: a protocol

    Stanciu, M. A., Law, R-J., Nafees, S., Hendry, M., Yeo, S. T., Hiscock, J., Lewis, R., Edwards, R., Williams, N., Brain, K., Brocklehurst, P., Carson-Stevens, A., Dolwani, S., Emery, J., Hamilton, W., Hoare, Z., Lyratzopoulos, G., Rubin, G., Smits, S., Vedsted, P., Walter, F., Wilkinson, C. & Neal, R., Oct 2018, In: British Journal of General Practice. 2, 3, bjgpopen18X101595.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Preserved re-experience of discrete emotions: Amnesia and executive function

    Stanciu, M. A., Rafal, R. D. & Turnbull, O. H., Jun 2019, In: Journal of Neuropsychology. 13, 2, p. 305-327

    Research output: Contribution to journalArticlepeer-review

  12. Published

    The risk of oesophago-gastric cancer in symptomatic patients in primary care: a large case–control study using electronic records

    Stapely, S., Peters, T. J., Neal, R. D., Rose, F. M. & Hamilton, W., 15 Jan 2013, In: British Journal of Cancer. 108, p. 25-31

    Research output: Contribution to journalArticlepeer-review

  13. Published

    The risk of pancreatic cancer in symptomatic patients in primary care: a large case–control study using electronic records

    Stapley, S., Peters, T. J., Neal, R. D., Rose, P., Walter, F. & Hamilton, W., 5 Jun 2012, In: British Journal of Cancer. 106, p. 1940-1944

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Diagnosis of Ovarian Cancer

    Sundar, S., Neal, R. D. & Kehoe, S., 1 Sept 2015, In: BMJ. 351, p. h4443

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Aripiprazole in the Maintenance Treatment of Bipolar Disorder: A Critical Review of the Evidence and Its Dissemination into the Scientific Literature

    Tsai, A. C., Rosenlicht, N., Jureidini, J., Parry, P. I., Spielmans, G. & Healy, D., 3 May 2011, In: PLoS Medicine. 8, 5, p. e1000434

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Achieving earlier diagnosis of symptomatic cervical cancer

    Walter, F. M., Mwaka, A. D. & Neal, R. D., 1 Oct 2014, In: British Journal of General Practice. 64, p. 495-496

    Research output: Contribution to journalArticlepeer-review

  17. Published

    Symptoms, unmet needs, psychological well-being and health status in survivors of prostate cancer: implications for redesigning follow-up

    Watson, E., Shinkins, B., Frith, E., Neal, D., Hamdy, F., Walter, F., Weller, D., Wilkinson, C., Faithfull, S., Wolstenholme, J., Sooriakumaran, P., Kastner, C., Campbell, C., Neal, R., Butcher, H., Matthews, M., Perera, R. & Rose, P., Jun 2016, In: BJUI International. 117, 6B, p. E10-E19

    Research output: Contribution to journalArticlepeer-review

  18. Published

    The Aarhus statement: improving design and reporting of studies on early cancer diagnosis

    Weller, D., Vedsted, P., Rubin, G., Walter, F., Emery, J., Scott, S., Campbell, C., Andersen, R. S., Hamilton, W., Olesen, F., Rose, P., Nafees, S., vanRijswijk, E., Muth, C., Beyer, M. & Neal, R. D., 27 Mar 2012, In: British Journal of Cancer. 106, p. 1262-1267

    Research output: Contribution to journalArticlepeer-review

  19. Published

    Diagnostic routes and time intervals for patients with colorectal cancer in 10 international jurisdictions; findings from a cross-sectional study from the International Cancer Benchmarking Partnership (ICBP)

    Weller, D., Menon, U., Falborg, A. Z., Jensen, H., Barisic, A., Knudsen, A. K., Bergin, R. J., Brewster, D., Cairnduff, V., Gavin, A. T., Grunfeld, E., Harland, E., Lambe, M., Law, R-J., Lin, Y., Malmberg, M., Tober, D., Neal, R., White, V., Harrison, S. & Reguilon, I., 27 Nov 2018, In: BMJ Open. 8, 11, e023870.

    Research output: Contribution to journalArticlepeer-review

  20. Published

    An investigation of routes to cancer diagnosis in 10 international jurisdictions, as part of the International Cancer Benchmarking Partnership: Survey development and implementation

    Weller, D., Vedsted, P., Anandan, C., Zalounina, A., Fourkala, E. O., Desai, R., Liston, W., Jensen, H., Barisic, A., Gavin, A., Grunfeld, E., Lambe, M., Law, R-J., Malmberg, M., Neal, R. D., Kalsi, J., Turner, D., White, V., Bomb, M. & Menon, U., 1 Jul 2016, In: BMJ Open. 6, 7

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Mortality in schizophrenia and related psychoses: data from two cohorts, 1875–1924 and 1994–2010

    Whitaker, C. J., Le Noury, J. C., Healy, D., Le Noury, J., Harris, M., Butt, M., Linden, S., Whitaker, C., Zou, L. & Roberts, A. P., 8 Oct 2012, In: BMJ Open. 2, 5, p. e001810

    Research output: Contribution to journalArticlepeer-review

  22. Published

    The incidence and prevalence of admissions for melancholia in two cohorts (1875–1924 and 1995–2005)

    Whitaker, C. J., Le Noury, J. C., Harris, M., Farquhar, F., Healy, D., Le Noury, J., Baker, D., Whitaker, C., Linden, S., Green, P. & Roberts, A. P., 1 Nov 2011, In: Journal of Affective Disorders. 134, 1-3, p. 45-51

    Research output: Contribution to journalArticlepeer-review

  23. Published

    Intervention Now to Eliminate Repeat Unintended Pregnancy in Teenagers (INTERUPT): a systematic review of intervention effectiveness and cost-effectiveness, and qualitative and realist synthesis of implementation factors and user engagement

    Whitaker, R., Hendry, M., Aslam, R., Booth, A., Carter, B., Charles, J., Craine, N., Edwards, R., Noyes, J., Ntambwe, L. I., Pasterfield, D., Rycroft-Malone, J. & Williams, N., 1 Mar 2016, In: Health Technology Assessment. 20, 16

    Research output: Contribution to journalArticlepeer-review

  24. Published

    Health professionals’ perspectives on exercise referral and physical activity promotion in primary care: Findings from a process evaluation of the National Exercise Referral Scheme in Wales

    Wilkinson, C. E., Din, N. U., Moore, G. F., Murphy, S., Wilkinson, C. & Williams, N. H., 1 Nov 2015, In: Health Education Journal. 74, 6, p. 743-757

    Research output: Contribution to journalArticlepeer-review

  25. Published

    Factors associated with intrusive cancer-related worries in women undergoing cancer genetic risk assessment

    Wilkinson, C. E., Bennett, P., Wilkinson, C., Turner, J., Edwards, R. T., France, B., Griffith, G. & Gray, J., 1 Sept 2009, In: Familial Cancer. 8, 3

    Research output: Contribution to journalArticlepeer-review

  26. Published

    The expanding role of primary care in cancer control

    Wilkinson, C. E., Rubin, G., Berendsen, A., Crawford, S. M., Dommett, R., Earle, C., Emery, J., Fahey, T., Grassi, L., Grunfeld, E., Gupta, S., Hamilton, W., Hiom, S., Hunter, D., Lyratzopoulos, G., Maclead, U., Mason, R., Mitchell, G., Neal, R. D., Peake, M., Roland, M., Seifert, B., Sisler, J., Sussman, J., Taplin, S., Vedsted, P., Voruganti, T., Walter, F., Wardle, J., Watson, E., Weller, D., Wender, R., Whelan, J., Whitlock, J., Wilkinson, C., de Wit, N. & Zimmerman, C., 1 Sept 2015, In: Lancet Oncology. 16, 12, p. 1231–1272

    Research output: Contribution to journalArticlepeer-review

  27. Published

    Functional illness in primary care: dysfunction versus disease

    Wilkinson, C. E., Williams, N. H., Williams, N., Wilkinson, C., Stott, N. & Menkes, D. B., 15 May 2008, In: BMC Family Practice. 9, 30, p. 1-8

    Research output: Contribution to journalArticlepeer-review

  28. Published

    Views of health professionals on the role of primary care in the follow-up of men with prostate cancer

    Wilkinson, C. E., Watson, E., O'Brien, R., Campbell, C., Weller, D., Neal, R. D., Wilkinson, C. & Rose, P. O., 21 Jun 2011, In: Family Practice. 28, 6, p. 647-654

    Research output: Contribution to journalArticlepeer-review

  29. Published

    Anxiety, depression and quality of life after cancer diagnosis: what psychosocial variables best predict how patients adjust?

    Wilkinson, C. E., Morrison, V. L., Hulbert-Williams, N. J., Neal, R. D., Morrison, V., Hood, K. & Wilkinson, C., 1 Aug 2012, In: Psycho-Oncology. 21, 8, p. 857-867

    Research output: Contribution to journalArticlepeer-review

  30. Published

    The effect of waiting times from general practitioner referral to MRI or orthopaedic consultation for the knee on patient-based outcomes

    Wilkinson, C. E., Brearly, S., Andronis, L., Dale, V., Gibbon, A. J., Gilbert, F. J., Hendry, M., Hood, K., King, D. & Wilkinson, C. O., 1 Nov 2012, In: British Journal of Radiology. 85, 1019, p. 1134-1139

    Research output: Contribution to journalArticlepeer-review

  31. Published

    “I wish I’d told them”: A qualitative study examining the unmet psychosexual needs of prostate cancer patients during follow-up after treatment

    Wilkinson, C. E., O’Brien, R., Rose, P., Campbell, C., Weller, D., Neal, R. D., Wilkinson, C., Mcintosh, H. & Watson, E., 1 Aug 2011, In: Patient Education and Counseling. 84, 2, p. 200-207

    Research output: Contribution to journalArticlepeer-review

  32. Published

    PROSPECTIV—a pilot trial of a nurse-led psychoeducational intervention delivered in primary care to prostate cancer survivors: study protocol for a randomised controlled trial

    Wilkinson, C. E., Watson, E., Rose, P., Frith, E., Hamdy, F., Neal, D., Kastner, C., Russell, S., Walter, F. M., Faithfull, S., Wolstenholme, J., Perera, R., Weller, D., Campbell, C., Wilkinson, C., Neal, R. D., Sooriakumaran, P., Butcher, H. & Matthews, M., 22 May 2014, In: BMJ Open. 4, 5, e005186.

    Research output: Contribution to journalArticlepeer-review

  33. Published

    A survey of local health promotion initiatives for older people in Wales

    Wilkinson, C. E., Hendry, M., Williams, N. H. & Wilkinson, C., 20 Jun 2008, In: BMC Public Health. 8, 217

    Research output: Contribution to journalArticlepeer-review

  34. Published

    Follow-up care for men with prostate cancer and the role of primary care: a systematic review of international guidelines

    Wilkinson, C. E., McIntosh, H. M., Neal, R. D., Rose, P., Watson, E., Wilkinson, C., Weller, D. & Campbell, C. O., 12 May 2009, In: British Journal of Cancer. 100, p. 1852–1860

    Research output: Contribution to journalArticlepeer-review

  35. Published

    Personalised cancer follow-up: risk stratification, needs assessment or both?

    Wilkinson, C. E., Watson, E. K., Rose, P. W., Neal, R. D., Hulbert-Williams, N., Donnelly, P., Hubbard, G., Elliot, J., Campbell, C., Weller, D. & Wilkinson, C., 3 Jan 2012, In: British Journal of Cancer. 106, p. 1-5

    Research output: Contribution to journalArticlepeer-review

  36. Published

    Investigating the cognitive precursors of emotional response to cancer stress: Re-testing Lazarus's transactional model

    Wilkinson, C. E., Morrison, V. L., Hulbert-Williams, N. J., Morrison, V., Wilkinson, C. & Neal, R. D., 1 Feb 2013, In: British Journal of Health Psychology. 18, 1, p. 97-121

    Research output: Contribution to journalArticlepeer-review

  37. Published

    ‘A false sense of security’? Understanding the role of the HPV vaccine on future cervical screening behaviour: a qualitative study of UK parents and girls of vaccination age

    Wilkinson, C. E., Henderson, L., Clements, A., Damery, S., Wilkinson, C., Austoker, J. & Wilson, S. O., 1 Mar 2011, In: Journal of Medical Screening. 18, 1, p. 41-45

    Research output: Contribution to journalArticlepeer-review

  38. Published

    “HPV? Never heard of it!”: A systematic review of girls’ and parents’ information needs, views and preferences about human papillomavirus vaccination

    Wilkinson, C. E., Lewis, R. A., Hendry, M., Clements, A. & Damery, S., 9 Sept 2013, In: Vaccine. 31, 45, p. 5152-5167

    Research output: Contribution to journalArticlepeer-review

  39. Published

    Effectiveness of GP access to magnetic resonance imaging of the knee: a randomised trial

    Wilkinson, C. E. & DAMASK Direct Access to Magnetic Resonance Imaging Assessment for Suspect Knees Trial Team, N. V., 1 Nov 2008, In: British Journal of General Practice. 58, 556, p. e1-e9

    Research output: Contribution to journalArticlepeer-review

  40. Published

    Determining patient and primary care delay in the diagnosis of cancer – lessons from a pilot study of patients referred for suspected cancer

    Wilkinson, C. E., Neal, R. D., Neal, R., Pasterfield, D., Wilkinson, C., Hood, K., Makin, M. K. & Lawrence H.*, N. V., 30 Jan 2008, In: BMC Family Practice. 9, 9

    Research output: Contribution to journalArticlepeer-review

  41. Published

    Cost-effectiveness of magnetic resonance imaging of the knee for patients presenting in primary care

    Wilkinson, C. E. & DAMASK Direct Access to Magnetic Resonance Imaging Assessment for Suspect Knees Trial Team, N. V., 1 Nov 2008, In: British Journal of General Practice. 58, 556, p. e10-e16

    Research output: Contribution to journalArticlepeer-review

  42. Published

    Measuring illness and exercise beliefs in osteoarthritis of the hip or knee: psychometric properties of the ‘Hip and Knee Beliefs Questionnaire’ and the ‘Exercise Attitude Questionnaire’

    Williams, N. H., Amoakwa, E., Belcher, J., Burton, K., Hendry, M., Lewis, R., Hood, K., Bennett, P., Neal, R. D. & Wilkinson, C. E., 1 Apr 2012, In: International Musculoskeletal Medicine. 34, 1, p. 13-20

    Research output: Contribution to journalArticlepeer-review

  43. Published

    The Hip and Knee Book: developing an active management booklet for hip and knee osteoarthritis

    Williams, N. H., Amoakwa, E., Burton, K., Hendry, M., Lewis, R., Jones, J., Bennett, P., Neal, R. D., Andrew, G. & Wilkinson, C. E., 1 Feb 2010, In: British Journal of General Practice. 60, 571, p. e64-e82

    Research output: Contribution to journalArticlepeer-review

  44. Published

    Can we be more specific about back and neck pain?

    Williams, N. H., 1 Mar 2009, In: International Musculoskeletal Medicine. 31, 1, p. 5-14

    Research output: Contribution to journalArticlepeer-review

  45. Published

    Healthy eating and lifestyle in pregnancy (HELP): a protocol for a cluster randomised trial to evaluate the effectiveness of a weight management intervention in pregnancy

    Williams, N. H., John, E., Cassidy, D. M., Playle, R., Jewell, K., Cohen, D., Duncan, D., Newcombe, R. G., Busse, M., Owen-Jones, E., Williams, N., Longo, M., Avery, A. & Simpson, S. A., 10 May 2014, In: BMC Public Health. 14, 439

    Research output: Contribution to journalArticlepeer-review

  46. Published

    “The wise, for cure, on exercise depend”: physical activity interventions in primary care in Wales

    Williams, N. H., 1 Feb 2009, In: British Journal of Sports Medicine. 43, 2, p. 106-108

    Research output: Contribution to journalArticlepeer-review

  47. Published

    Activity Increase Despite Arthritis (AÏDA): phase II randomised controlled trial of an active management booklet for hip and knee osteoarthritis in primary care

    Williams, N. H., Amoakwa, E., Belcher, J., Edwards, R. T., Hassani, H., Hendry, M., Burton, K., Lewis, R., Hood, K., Jones, J., Bennett, P., Linck, P. G., Neal, R. D. & Wilkinson, C. E., 1 Aug 2011, In: British Journal of General Practice. 61, 589, p. e452-e458

    Research output: Contribution to journalArticlepeer-review

  48. Published

    Activity Increase Despite Arthritis (AÏDA): design of a Phase II randomised controlled trial evaluating an active management booklet for hip and knee osteoarthritis [ISRCTN24554946]

    Williams, N., Amoakwa, E., Burton, K., Hendry, M., Belcher, J., Lewis, R., Hood, K., Jones, J. G., Bennett, P., Edwards, R. T., Neal, R., Andrew, G. & Wilkinson, C., 4 Sept 2009, In: BMC Family Practice. 10, 62, p. 1-9 62.

    Research output: Contribution to journalArticlepeer-review

  49. Published

    Effectiveness of exercise-referral schemes to promote physical activity in adults: systematic review

    Williams, N. H., Hendry, M., France, B., Lewis, R. & Wilkinson, C., Dec 2007, In: British Journal of General Practice. 57, 545, p. 979-86 8 p.

    Research output: Contribution to journalArticlepeer-review

  50. Published

    A systematic review and meta-analysis of biological treatments targeting tumour necrosis factor α for sciatica

    Williams, N. H., Lewis, R., Din, N. U., Matar, H. E., Fitzsimmons, D., Phillips, C. J., Sutton, A., Burton, K., Hendry, M., Nafees, S. & Wilkinson, C., Sept 2013, In: European Spine Journal. 22, 9, p. 1921-35 15 p.

    Research output: Contribution to journalArticlepeer-review

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