[Pre-Aug 2018] North Wales Centre for Primary Care Research

  1. Article › Research › Peer-reviewed
  2. Published

    A feasibility study examining the effect on lung cancer diagnosis of offering a chest X-ray to higher-risk patients with chest symptoms: protocol for a randomized controlled trial

    Hurt, C. N., Roberts, K., Rogers, T. K., Griffiths, G. O., Hood, K., Prout, H., Nelson, A., Fitzgibbon, J., Barham, A., Thomas-Jones, E., Edwards, R. T., Yeo, S. T., Hamilton, W., Tod, A. & Neal, R. D., 26 Nov 2013, In : Trials. 14, p. 405

    Research output: Contribution to journalArticle

  3. Published

    A pilot randomised controlled trial of personalised care after treatment for prostate cancer (TOPCAT-P): nurse-led holistic-needs assessment and individualised psychoeducational intervention: study protocol

    Evans, R. J., Hoare, Z. S., Wilkinson, C. E., Stanciu, M. A., Makin, M., Watson, E., Bulger, J., Evans, R., Hiscock, J., Hoare, Z., Edwards, R. T., Neal, R. D. & Wilkinson, C., 25 Jun 2015, In : BMJ Open. 5, 6

    Research output: Contribution to journalArticle

  4. Published

    A pragmatic randomised controlled trial of the Welsh National Exercise Referral Scheme: protocol for trial and integrated economic and process evaluation

    Murphy, S., Raisanen, L., Moore, G., Edwards, R. T., Linck, P., Williams, N., Din, N., Hale, J., Roberts, C., McNaish, E. & Moore, L., 18 Jun 2010, In : BMC Public Health. 10, 352, p. 352

    Research output: Contribution to journalArticle

  5. Published

    A stepped wedge cluster randomized control trial of dried blood spot testing to improve the uptake of hepatitis C antibody testing within UK prisons

    Craine, N., Whitaker, R., Perrett, S., Zou, L., Hickman, M. & Lyons, M., 24 Jul 2014, In : European Journal of Public Health. 25, 2, p. 351-357

    Research output: Contribution to journalArticle

  6. Published

    A survey of local health promotion initiatives for older people in Wales

    Wilkinson, C. E., Hendry, M., Williams, N. H. & Wilkinson, C., 20 Jun 2008, In : BMC Public Health. 8, 217

    Research output: Contribution to journalArticle

  7. Published

    A systematic review and meta-analysis of biological treatments targeting tumour necrosis factor α for sciatica

    Williams, N. H., Lewis, R., Din, N. U., Matar, H. E., Fitzsimmons, D., Phillips, C. J., Sutton, A., Burton, K., Hendry, M., Nafees, S. & Wilkinson, C., Sep 2013, In : European Spine Journal. 22, 9, p. 1921-35 15 p.

    Research output: Contribution to journalArticle

  8. Published

    Achieving earlier diagnosis of symptomatic cervical cancer

    Walter, F. M., Mwaka, A. D. & Neal, R. D., 1 Oct 2014, In : British Journal of General Practice. 64, p. 495-496

    Research output: Contribution to journalArticle

  9. Published

    Activity Increase Despite Arthritis (AÏDA): design of a Phase II randomised controlled trial evaluating an active management booklet for hip and knee osteoarthritis [ISRCTN24554946]

    Williams, N., Amoakwa, E., Burton, K., Hendry, M., Belcher, J., Lewis, R., Hood, K., Jones, J. G., Bennett, P., Edwards, R. T., Neal, R., Andrew, G. & Wilkinson, C., 4 Sep 2009, In : BMC Family Practice. 10, 62, p. 1-9 62.

    Research output: Contribution to journalArticle

  10. Published

    Activity Increase Despite Arthritis (AÏDA): phase II randomised controlled trial of an active management booklet for hip and knee osteoarthritis in primary care

    Williams, N. H., Amoakwa, E., Belcher, J., Edwards, R. T., Hassani, H., Hendry, M., Burton, K., Lewis, R., Hood, K., Jones, J., Bennett, P., Linck, P. G., Neal, R. D. & Wilkinson, C. E., 1 Aug 2011, In : British Journal of General Practice. 61, 589, p. e452-e458

    Research output: Contribution to journalArticle

  11. Published

    Adolescent Cancer Education (ACE) to increase adolescent and parent cancer awareness and communication: study protocol for a cluster randomised controlled trial

    Kyle, R. G., Macmillan, I., Rauchhaus, P., O'Carroll, R., Neal, R. D., Forbat, L., Haw, S. & Hubbard, G., 8 Sep 2013, In : Trials. 14, 286, p. 1-10

    Research output: Contribution to journalArticle

  12. Published

    Age and Gender Variations in Cancer Diagnostic Intervals in 15 Cancers: Analysis of Data from the UK Clinical Practice Research Datalink

    Din, N. U., Ukoumunne, O. C., Rubin, G., Hamilton, W., Carter, B., Stapley, S. & Neal, R. D., 15 May 2015, In : PLoS ONE. 10, 5

    Research output: Contribution to journalArticle

  13. Published

    Alpha adrenoceptor agonist-induced microcirculatory oscillations are reduced in diabetic neuropathy.

    Schmiedel, O., Nurmikko, T. J., Schroeter, M. L., Whitaker, R. & Harvey, J. N., 1 Aug 2008, In : Microvascular Research. 76, 2, p. 124-131

    Research output: Contribution to journalArticle

  14. Published

    An Association of Cancer Physicians' strategy for improving services and outcomes for cancer patients

    Neal, R. D., Baird, R., Banks, I., Cameron, D., Chester, J., Earl, H., Flannagan, M., Januszewski, A., Kennedy, R., Payne, S., Samuel, E., Taylor, H., Agarwal, R., Ahmed, S., Archer, C., Board, R., Carser, J., Copson, E., Cunningham, D., Coleman, R., Glaser, A., Griffiths, R., Hall, G., Hall, M., Harari, D., Hawkins, M., Hill, M., Johnson, P., Jones, A., Kalsi, T., Karapanagiotou, E., Kemp, Z., Mansi, J., Marshall, E., Mitchell, A., Moe, M., Michie, C., Neal, R., Newsom-Davis, T., Norton, A., Osborne, R., Patel, G., Radford, J., Ring, A., Shaw, E., Skinner, R., Stark, D., Turnbull, S., Velikova, G., White, J., Young, A., Joffe, J. & Selby, P., 5 Jan 2016, In : Ecancermedical Science. 10, 608

    Research output: Contribution to journalArticle

  15. Published

    An evaluation of the effectiveness and cost effectiveness of the National Exercise Referral Scheme in Wales, UK: a randomised controlled trial of a public health policy initiative

    Murphy, S. M., Edwards, R. T., Williams, N., Raisanen, L., Moore, G., Linck, P., Hounsome, N., Din, N. U. & Moore, L., Aug 2012, In : Journal of Epidemiology and Community Health. 66, 8, p. 745-753 9 p.

    Research output: Contribution to journalArticle

  16. Published

    An investigation of routes to cancer diagnosis in 10 international jurisdictions, as part of the International Cancer Benchmarking Partnership: Survey development and implementation

    Weller, D., Vedsted, P., Anandan, C., Zalounina, A., Fourkala, E. O., Desai, R., Liston, W., Jensen, H., Barisic, A., Gavin, A., Grunfeld, E., Lambe, M., Law, R-J., Malmberg, M., Neal, R. D., Kalsi, J., Turner, D., White, V., Bomb, M. & Menon, U., 1 Jul 2016, In : BMJ Open. 6, 7

    Research output: Contribution to journalArticle

  17. Published

    Anxiety, depression and quality of life after cancer diagnosis: what psychosocial variables best predict how patients adjust?

    Wilkinson, C. E., Morrison, V. L., Hulbert-Williams, N. J., Neal, R. D., Morrison, V., Hood, K. & Wilkinson, C., 1 Aug 2012, In : Psycho-Oncology. 21, 8, p. 857-867

    Research output: Contribution to journalArticle

  18. Published

    Are women ready for the new cervical screening protocol in England? A systematic review and qualitative synthesis of views about human papillomavirus testing

    Hendry, M., Pasterfield, D., Lewis, R., Clements, A., Damery, S., Neal, R. D., Adke, R., Weller, D., Campbell, C., Patnick, J., Sasieni, P., Hurt, C., Wilson, S. & Wilkinson, C. E., 14 Jul 2012, In : British Journal of Cancer. 107, p. 243-254

    Research output: Contribution to journalArticle

  19. Published

    Aripiprazole in the Maintenance Treatment of Bipolar Disorder: A Critical Review of the Evidence and Its Dissemination into the Scientific Literature

    Tsai, A. C., Rosenlicht, N., Jureidini, J., Parry, P. I., Spielmans, G. & Healy, D., 3 May 2011, In : PLoS Medicine. 8, 5, p. e1000434

    Research output: Contribution to journalArticle

  20. Published

    Can we be more specific about back and neck pain?

    Williams, N. H., 1 Mar 2009, In : International Musculoskeletal Medicine. 31, 1, p. 5-14

    Research output: Contribution to journalArticle

  21. Published

    Cancer symptom awareness and barriers to medical help seeking in Scottish adolescents: a cross-sectional study

    Hubbard, G., Macmillan, I., Canny, A., Forbat, L., Neal, R. D., O'Carroll, R. E., Haw, S. & Kyle, R. G., 29 Oct 2014, In : BMC Public Health. 14, 1117

    Research output: Contribution to journalArticle

  22. Published

    Clinical features of bladder cancer in primary care

    Shephard, E., Stapley, S., Neal, R. D., Rose, P., Walter, F. & Hamilton, W. T., 1 Sep 2012, In : British Journal of General Practice. 62, 602, p. e598-604

    Research output: Contribution to journalArticle

  23. Published

    Clinical features of kidney cancer in primary care: a case-control study using primary care records

    Neal, R. D., Shepherd, E., Neal, R., Rose, P., Walter, F. & Hamilton, W. T., 1 Apr 2013, In : British Journal of General Practice. 63, 609, p. e250-e255

    Research output: Contribution to journalArticle

  24. Published

    Comparative Effectiveness of Dabigatran, Rivaroxaban, Apixaban, and Warfarin in the Management of Patients With Nonvalvular Atrial Fibrillation

    Hughes, D., Pink, J., Pirmohamed, M. & Hughes, D. A., 25 Apr 2013, In : Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journalArticle

  25. Published

    Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database

    Neal, R. D., Din, N. U., Hamilton, W., Ukoumunne, O. C., Carter, B., Stapley, S. & Rubin, G., 4 Feb 2014, In : British Journal of Cancer. 110, 3, p. 584–592 9 p.

    Research output: Contribution to journalArticle

  26. Published

    Cordotomy in mesothelioma-related pain: a systematic review

    France, B. D., Lewis, R. A., Sharma, M. L. & Poolman, M., 1 Mar 2014, In : BMJ Supportive and Palliative Care. 4, 1, p. 19-29

    Research output: Contribution to journalArticle

  27. Published

    Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation

    Hughes, D., Pink, J., Pirmohamed, M., Lane, S. & Hughes, D. A., 23 Sep 2013, In : Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journalArticle

  28. Published

    Cost-effectiveness of a national exercise referral programme for primary care patients in Wales: results of a randomised controlled trial

    Linck, P. G., Williams, N. H., Edwards, R. T., Linck, P., Hounsome, N., Raisanen, L., Williams, N., Moore, L. & Murphy, S., 29 Oct 2013, In : BMC Public Health. 13, p. 1021

    Research output: Contribution to journalArticle

  29. Published

    Cost-effectiveness of different strategies to manage patients with sciatica

    Fitzimmons, D., Phillips, C. J., Bennett, H., Jones, M., Williams, N. H., Lewis, R., Sutton, A., Matar, H. E., Din, N. U., Burton, K., Nafees, S., Hendry, M., Rickard, I. & Wilkinson, C. E., Jul 2014, In : Pain. 155, 7, p. 1318-1327 10 p.

    Research output: Contribution to journalArticle

  30. Published

    Cost-effectiveness of magnetic resonance imaging of the knee for patients presenting in primary care

    Wilkinson, C. E. & DAMASK Direct Access to Magnetic Resonance Imaging Assessment for Suspect Knees Trial Team, N. V., 1 Nov 2008, In : British Journal of General Practice. 58, 556, p. e10-e16

    Research output: Contribution to journalArticle

  31. Published

    Determining patient and primary care delay in the diagnosis of cancer – lessons from a pilot study of patients referred for suspected cancer

    Wilkinson, C. E., Neal, R. D., Neal, R., Pasterfield, D., Wilkinson, C., Hood, K., Makin, M. K. & Lawrence H.*, N. V., 30 Jan 2008, In : BMC Family Practice. 9, 9

    Research output: Contribution to journalArticle

  32. Published

    Deterministic nonlinear features of cutaneous perfusion are lost in diabetic subjects with neuropathy

    Parthimos, D., Schmiedel, O., Harvey, J. N. & Griffith, T. M., 1 Jul 2011, In : Microvascular Research. 82, 1, p. 42-51

    Research output: Contribution to journalArticle

  33. Published

    Development of a survey instrument to investigate the primary care factors related to differences in cancer diagnosis between international jurisdictions

    Rose, P. W., Hamilton, W., Aldersey, K., Barisic, A., Dawes, M., Foot, C., Grunfeld, E., Hart, N., Neal, R. D., Pirotta, M., Sisler, J., Thulesius, H., Vedsted, P., Young, J. & Rubin, G., 17 Jun 2014, In : BMC Family Practice. 2014, 15, p. 122

    Research output: Contribution to journalArticle

  34. Published

    Development of an intervention to expedite cancer diagnosis through primary care: a protocol

    Stanciu, M. A., Law, R-J., Nafees, S., Hendry, M., Yeo, S. T., Hiscock, J., Lewis, R., Edwards, R., Williams, N., Brain, K., Brocklehurst, P., Carson-Stevens, A., Dolwani, S., Emery, J., Hamilton, W., Hoare, Z., Lyratzopoulos, G., Rubin, G., Smits, S., Vedsted, P., Walter, F., Wilkinson, C. & Neal, R., Oct 2018, In : British Journal of General Practice. 2, 3, bjgpopen18X101595.

    Research output: Contribution to journalArticle

  35. Published

    Dextrin-colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections

    Ferguson, E. L., Azzopardi, E., Roberts, J. L., Walsh, T. R. & Thomas, D. W., 31 Oct 2014, In : Molecular Pharmaceutics. 11, 12, p. 4437-47 11 p.

    Research output: Contribution to journalArticle

  36. Published

    Diabetes in children in Wales – the work of the Brecon Group

    Harvey, J. N. & Hawkes, D., 1 Jan 2010, In : Welsh Paediatric Journal. 34, p. 7-9

    Research output: Contribution to journalArticle

  37. Published

    Diabetes, metformin and lactic acidosis

    Scale, T. & Harvey, J. N., 1 Feb 2011, In : Clinical Endocrinology. 74, 2, p. 191-196

    Research output: Contribution to journalArticle

  38. Published

    Diagnosis of Ovarian Cancer

    Sundar, S., Neal, R. D. & Kehoe, S., 1 Sep 2015, In : BMJ. 351, p. h4443

    Research output: Contribution to journalArticle

  39. Published

    Diagnostic routes and time intervals for patients with colorectal cancer in 10 international jurisdictions; findings from a cross-sectional study from the International Cancer Benchmarking Partnership (ICBP)

    Weller, D., Menon, U., Falborg, A. Z., Jensen, H., Barisic, A., Knudsen, A. K., Bergin, R. J., Brewster, D., Cairnduff, V., Gavin, A. T., Grunfeld, E., Harland, E., Lambe, M., Law, R-J., Lin, Y., Malmberg, M., Tober, D., Neal, R., White, V., Harrison, S. & Reguilon, I., 27 Nov 2018, In : BMJ Open. 8, 11, e023870.

    Research output: Contribution to journalArticle

  40. Published

    Diagnostic value of symptoms of oesophagogastric cancers in primary care: a systematic review and meta-analysis

    Astin, M. P., Martins, T., Welton, N., Neal, R. D., Rose, P. W. & Hamilton, W., 1 Oct 2015, In : British Journal of General Practice. 65, 639

    Research output: Contribution to journalArticle

  41. Published

    Do diagnostic delays in cancer matter?

    Neal, R. D., 1 Jan 2009, In : British Journal of Cancer. 101, p. S9-S12

    Research output: Contribution to journalArticle

  42. Published

    Effectiveness of GP access to magnetic resonance imaging of the knee: a randomised trial

    Wilkinson, C. E. & DAMASK Direct Access to Magnetic Resonance Imaging Assessment for Suspect Knees Trial Team, N. V., 1 Nov 2008, In : British Journal of General Practice. 58, 556, p. e1-e9

    Research output: Contribution to journalArticle

  43. Published

    Effectiveness of exercise-referral schemes to promote physical activity in adults: systematic review

    Williams, N. H., Hendry, M., France, B., Lewis, R. & Wilkinson, C., Dec 2007, In : British Journal of General Practice. 57, 545, p. 979-86 8 p.

    Research output: Contribution to journalArticle

  44. Published

    Enhancing ventilation in homes of children with asthma: cost-effectiveness study alongside randomised controlled trial

    Linck, P. G., Edwards, R. T., Neal, R. D., Linck, P., Bruce, N., Mullock, L., Nelhans, N., Pasterfield, D., Russell, D., Russell, I. & Woodfine, L. O., 1 Nov 2011, In : British Journal of General Practice. 61, 592, p. e733-e741

    Research output: Contribution to journalArticle

  45. Published

    Enhancing ventilation in homes of children with asthma: pragmatic randomised controlled trial

    Linck, P. G., Woodfine, L., Neal, R. D., Bruce, N., Edwards, R. T., Linck, P., Mullock, L., Nelhans, N., Pasterfield, D., Russell, D. & Russell, I. O., 1 Nov 2011, In : British Journal of General Practice. 61, 592, p. e724-e732

    Research output: Contribution to journalArticle

  46. Published

    Excision of malignant melanomas in North Wales: effect of location and surgeon on time to diagnosis and quality of excision

    Neal, R. D., Cannings-John, R. L., Hood, K., Sowden, J., Lawrence, H., Jones, C. & Jones, J., 1 Aug 2008, In : Family Practice. 25, 4, p. 221-227

    Research output: Contribution to journalArticle

  47. Published

    Experiences of follow-up after treatment in patients with prostate cancer: a qualitative study

    O'Brien, R., Rose, P. W., Campbell, C., Weller, D., Neal, R. D., Wilkinson, C., Watson, E. K. & Prostate Cancer Follow-up Group, Oct 2010, In : BJUI International. 106, 7, p. 998-1003 6 p.

    Research output: Contribution to journalArticle

  48. Published

    Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey

    Rose, P. W., Rubin, G., Perera-Salazar, R., Almberg, S. S., Barisic, A., Dawes, M., Grunfeld, E., Hart, N., Neal, R. D., Pirotta, M., Sisler, J., Konrad, G., Toftegaard, B. S., Thulesius, H., Vedsted, P., Young, J., Hamilton, W. & The ICBP Module 3 Working Group., N. V., 27 May 2015, In : BMJ Open. 5, 5

    Research output: Contribution to journalArticle

  49. Published

    Factors associated with intrusive cancer-related worries in women undergoing cancer genetic risk assessment

    Wilkinson, C. E., Bennett, P., Wilkinson, C., Turner, J., Edwards, R. T., France, B., Griffith, G. & Gray, J., 1 Sep 2009, In : Familial Cancer. 8, 3

    Research output: Contribution to journalArticle

  50. Published

    Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation

    Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Jul 2014, In : Health Technology Assessment. 18, 48, p. 1-159

    Research output: Contribution to journalArticle

  51. Published

    Follow-up care for men with prostate cancer and the role of primary care: a systematic review of international guidelines

    Wilkinson, C. E., McIntosh, H. M., Neal, R. D., Rose, P., Watson, E., Wilkinson, C., Weller, D. & Campbell, C. O., 12 May 2009, In : British Journal of Cancer. 100, p. 1852–1860

    Research output: Contribution to journalArticle

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