Dr Christopher Staples
Senior Lecturer in Biomedical Sciences (Cancer Biology)
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- Chapter › Research › Not peer-reviewed
- Published
Approaches for Identifying Novel Targets in Precision Medicine: Lessons from DNA Repair
Williams, D. T. & Staples, C., 25 Aug 2017, Personalised Medicine. El-Khamisy, S. (ed.). Springer, Vol. 1007. p. 1-16 16 p. (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Article › Research › Peer-reviewed
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Biophysical properties of salmonid alphaviruses: influence of temperature and pH on virus survival
Graham, D. A., Staples, C., Wilson, C. J., Jewhurst, H., Cherry, K., Gordon, A. & Rowley, H. M., Sept 2007, In: Journal of Fish Biology. 30, 9, p. 533-43 11 p.Research output: Contribution to journal › Article › peer-review
- Published
CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence
Crozier, L., Foy, R., adib, R., Kar, A., Holt, J., Pareri, A., Valverde, J., Riviera, R., Weston, W., Wilson, R., Regnault, C., Whitfield, P., Badonyi, M., Bennett, L., Vernon, E., Gamble, A., Marsh, J., Staples, C., Saurin, A., Barr, A. & Ly, T., 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4062-4077 15 p.Research output: Contribution to journal › Article › peer-review
- Published
Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability
Staples, C. J., Myers, K. N., Beveridge, R. D., Patil, A. A., Howard, A. E., Barone, G., Lee, A. J., Swanton, C., Howell, M., Maslen, S., Skehel, J. M., Boutlon, S. J. & Collis, S. J., 1 Jul 2014, In: Journal of Cell Science. 127, p. 2910-2919Research output: Contribution to journal › Article › peer-review
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Cross-talk between the p38alpha and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation
Staples, C. J., Owens, D. M., Maier, J. V., Cato, A. C. B. & Keyse, S. M., 20 Aug 2010, In: Journal of Biological Chemistry. 285, 34, p. 25928-40 13 p.Research output: Contribution to journal › Article › peer-review
Human CDK18 promotes replication stress signaling and genome stability
Barone, G., Staples, C. J., Ganesh, A., Patterson, K. W., Bryne, D. P., Myers, K. N., Patil, A. A., Eyers, C. E., Maslen, S., Skehel, J. M., Eyers, P. A. & Collis, S. J., 14 Oct 2016, In: Nucleic Acids Research. 44, 18, p. 8772-8785 14 p.Research output: Contribution to journal › Article › peer-review
- Published
MRNIP is a replication fork protection factor
Bennett, L., Wilkie, A., Antonopoulou, E., Ceppi, I., Sanchez, A., Vernon, E., Gamble, A., Myers, K. N., Collis, S. J., Cejka, P. & Staples, C., 10 Jul 2020, In: Science Advances. 6, 28, 10 p., eaba5974.Research output: Contribution to journal › Article › peer-review
- Published
MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response
Staples, C. J., Barone, G., Myers, K. N., Ganesh, A., Gibbs-Seymour, I., Patil, A. A., Beveridge, R. D., Daye, C., Beniston, R., Maslen, S., Ahel, I., Skehel, J. M. & Collis, S. J., 6 Sept 2016, In: Cell. 16, 10, p. 2565-75 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter
Ekerot, M., Stavridis, M. P., Delavaine, L., Mitchell, M. P., Staples, C., Owens, D. M., Keenan, I. D., Dickinson, R. J., Storey, K. G. & Keyse, S. M., 1 Jun 2008, In: Biochemical Journal. 412, 2, p. 287-98 12 p.Research output: Contribution to journal › Article › peer-review
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Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways
Dickinson, R. J., Delavaine, L., Cejudo-Marín, R., Stewart, G., Staples, C. J., Didmon, M. P., Trinidad, A. G., Alonso, A., Pulido, R. & Keyse, S. M., 4 Nov 2011, In: Journal of Biological Chemistry. 286, 44, p. 38018-26 9 p.Research output: Contribution to journal › Article › peer-review