Dr Christopher Staples

Senior Lecturer in Biomedical Sciences (Cancer Biology)

  1. Article › Research › Peer-reviewed
  2. Biophysical properties of salmonid alphaviruses: influence of temperature and pH on virus survival

    Graham, D. A., Staples, C., Wilson, C. J., Jewhurst, H., Cherry, K., Gordon, A. & Rowley, H. M., Sep 2007, In : Journal of Fish Biology. 30, 9, p. 533-43 11 p.

    Research output: Contribution to journalArticle

  3. Published

    Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

    Staples, C. J., Myers, K. N., Beveridge, R. D., Patil, A. A., Howard, A. E., Barone, G., Lee, A. J., Swanton, C., Howell, M., Maslen, S., Skehel, J. M., Boutlon, S. J. & Collis, S. J., 1 Jul 2014, In : Journal of Cell Science. 127, p. 2910-2919

    Research output: Contribution to journalArticle

  4. Cross-talk between the p38alpha and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation

    Staples, C. J., Owens, D. M., Maier, J. V., Cato, A. C. B. & Keyse, S. M., 20 Aug 2010, In : Journal of Biological Chemistry. 285, 34, p. 25928-40 13 p.

    Research output: Contribution to journalArticle

  5. Human CDK18 promotes replication stress signaling and genome stability

    Barone, G., Staples, C. J., Ganesh, A., Patterson, K. W., Bryne, D. P., Myers, K. N., Patil, A. A., Eyers, C. E., Maslen, S., Skehel, J. M., Eyers, P. A. & Collis, S. J., 14 Oct 2016, In : Nucleic Acids Research. 44, 18, p. 8772-8785 14 p.

    Research output: Contribution to journalArticle

  6. Published

    MRNIP is a replication fork protection factor

    Bennett, L., Wilkie, A., Antonopoulou, E., Ceppi, I., Sanchez, A., Vernon, E., Gamble, A., Myers, K. N., Collis, S. J., Cejka, P. & Staples, C., 10 Jul 2020, In : Science Advances. 6, 28, 10 p., eaba5974.

    Research output: Contribution to journalArticle

  7. Published

    MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

    Staples, C. J., Barone, G., Myers, K. N., Ganesh, A., Gibbs-Seymour, I., Patil, A. A., Beveridge, R. D., Daye, C., Beniston, R., Maslen, S., Ahel, I., Skehel, J. M. & Collis, S. J., 6 Sep 2016, In : Cell. 16, 10, p. 2565-75 11 p.

    Research output: Contribution to journalArticle

  8. Published

    Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter

    Ekerot, M., Stavridis, M. P., Delavaine, L., Mitchell, M. P., Staples, C., Owens, D. M., Keenan, I. D., Dickinson, R. J., Storey, K. G. & Keyse, S. M., 1 Jun 2008, In : Biochemical Journal. 412, 2, p. 287-98 12 p.

    Research output: Contribution to journalArticle

  9. Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways

    Dickinson, R. J., Delavaine, L., Cejudo-Marín, R., Stewart, G., Staples, C. J., Didmon, M. P., Trinidad, A. G., Alonso, A., Pulido, R. & Keyse, S. M., 4 Nov 2011, In : Journal of Biological Chemistry. 286, 44, p. 38018-26 9 p.

    Research output: Contribution to journalArticle

  10. Regulation of the inducible nuclear dual-specificity phosphatase DUSP5 by ERK MAPK

    Kucharska, A., Rushworth, L. K., Staples, C., Morrice, N. A. & Keyse, S. M., Dec 2009, In : Cellular Signalling. 21, 12, p. 1794-805 12 p.

    Research output: Contribution to journalArticle

  11. Published

    The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability

    Myers, K. N., Barone, G., Ganesh, A., Staples, C. J., Howard, A. E., Beveridge, R. D., Maslen, S., Skehel, J. M. & Collis, S. J., 14 Oct 2016, In : Scientific Reports. 6, p. 35548

    Research output: Contribution to journalArticle

  12. Published

    The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling

    Beveridge, R. D., Staples, C. J., Patil, A. A., Myers, K. N., Maslen, S., Skehel, J. M., Boulton, S. J. & Collis, S. J., 29 Oct 2014, In : Cell Cycle. 13, 21, p. 3450-3459

    Research output: Contribution to journalArticle

  13. Chapter › Research › Not peer-reviewed
  14. Published

    Approaches for Identifying Novel Targets in Precision Medicine: Lessons from DNA Repair

    Williams, D. T. & Staples, C., 25 Aug 2017, Personalised Medicine. El-Khamisy, S. (ed.). Springer, Vol. 1007. p. 1-16 16 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter