Dyfrig Hughes - Research outputs

Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 101-126

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

Clinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.

Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Jan 2004, In: Drug Safety. 27, 8, p. 535-554

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinence.

Hughes, D., Hughes, D. A. & Dubois, D., 1 Jan 2004, In: Pharmacoeconomics. 22, 16, p. 1047-1059

Research output: Contribution to journal › Article › peer-review

Published

Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Belgium.

Hughes, D. & Hughes, D. A., 1 Jan 2004, 2004 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Modelling in health economics

Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 141-154

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

The future challenges

Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group

Hughes, D. & Hughes, D. A., 1 Apr 2004.

Research output: Contribution to conference › Paper

Published

Pharmacoeconomics of pharmacogenetic testing: azathioprine

Hughes, D., McAllister, R. & Hughes, D. A., 1 Apr 2004.

Research output: Contribution to conference › Paper

Published

Patient compliance and persistence with prescribed medication: Measurement and health economic impact

Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 May 2004.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

Research output: Contribution to journal › Article › peer-review

Published

Introduction to pharmaeconomics

Hughes, D. & Hughes, D. A., 1 Jul 2004.

Research output: Contribution to conference › Paper

Published

Pharmacoeconomic models that incorporate non-compliance

Hughes, D. & Hughes, D. A., 1 Jul 2004.

Research output: Contribution to conference › Paper

Published

Pharmacoeconomics appraisals by the all Wales medicines strategy group

Hughes, D. & Hughes, D. A., 1 Jul 2004.

Research output: Contribution to conference › Paper

Published

The difference between effectiveness and efficacy of antimalarial drugs in Kenya.

Hughes, D., Amin, A. A., Hughes, D. A., Marsh, V., Abuya, T. O., Kokwaro, G. O., Winstanley, P. A., Ochala, S. A. & Snow, R. W., 1 Sept 2004, In: Tropical Medicine and International Health. 9, 9, p. 967-974

Research output: Contribution to journal › Article › peer-review

Published

Economic evaluation of on-demand maintenance therapy with proton pump inhibitors in patients with symptomatic gastroesophageal reflux disease - a Monte-Carlo analysis for Italy

Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Oct 2004.

Research output: Contribution to conference › Paper

Published

A single centre open phase IV study to evaluate the safety and tolerability of chlorproguanil-dapsone when dosed by defined height bands

Hughes, D., Makanga, M., Winstanley, P. & Hughes, D. A., 1 Nov 2004.

Research output: Contribution to conference › Paper

Published

Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease

Hughes, D. & Hughes, D. A., 1 Nov 2004, In: Value in Health. 7, 6, p. 753

Research output: Contribution to journal › Article › peer-review

Published

From efficacy to effectiveness and cost-effectiveness: modelling possibilities

Hughes, D. & Hughes, D. A., 1 Nov 2004.

Research output: Contribution to conference › Paper

Published

HLA-B*5701 and abacavir hypersensitivity - Reply.

Hughes, D., Hughes, D. A., Park, B. K. & Pirmohamed, M., 1 Nov 2004, In: Pharmacogenetics. 14, 11, p. 784

Research output: Contribution to journal › Article › peer-review

Published

Economic analysis of on-demand maintenance therapy with proton pump inhibitors in patients with non-erosive reflux disease.

Hughes, D., Hughes, D. A., Bodger, K., Bytzer, P., De Herdt, D. & Dubois, D., 1 Jan 2005, In: Pharmacoeconomics. 23, 10, p. 1031-1041

Research output: Contribution to journal › Article › peer-review

Published

Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Sweden.

Hughes, D. & Hughes, D. A., 1 Jan 2005, 2005 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Welsh Health Economics Network (WHEN): Scoping Report.

Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease.

Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Feb 2005, In: Expert Review of Pharmacoeconomics and Outcomes Research. 5, 1, p. 29-38

Research output: Contribution to journal › Article › peer-review

Published

Empirical analysis of the relationship between dose and duration of drug action

Hughes, D. & Hughes, D. A., 1 Jun 2005.

Research output: Contribution to conference › Paper

Published

Pharmacokinetics, patient compliance and pharmaeconomics

Hughes, D. & Hughes, D. A., 1 Jun 2005.

Research output: Contribution to conference › Paper

Published

Cisplatin plus vinorelbine or gemcitabine in patients with advanced non-small cell lung cancer: Pharmacoeconomic considerations.

Hughes, D. & Hughes, D. A., 1 Jul 2005, In: European Journal of Cancer. 41, 11, p. 1655

Research output: Contribution to journal › Article › peer-review

Published

Public funding of drugs for orphan diseases

Hughes, D. & Hughes, D. A., 1 Jul 2005.

Research output: Contribution to conference › Paper

Published

Drugs for exceptionally rare diseases: do they deserve special status for funding?

Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

Research output: Contribution to journal › Article › peer-review

Published

Incorporating measures of compliance and persistence in pharmacoeconomic evaluations

Hughes, D., Hughes, D. A. & Cowell, W., 1 Nov 2005.

Research output: Contribution to conference › Paper

Published

Public funding of drugs for orphan diseases

Hughes, D. & Hughes, D. A., 1 Nov 2005.

Research output: Contribution to conference › Paper

Published

Public funding of drugs for orphan diseases

Hughes, D. & Hughes, D. A., 1 Nov 2005.

Research output: Contribution to conference › Paper

Published

Trends and influences on use of antidiabetic drugs in England, 1992-2003.

Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773

Research output: Contribution to journal › Article › peer-review

Published

Public funding of drugs for orphan diseases

Hughes, D. & Hughes, D. A., 11 Nov 2005, In: Value in Health. 8, 6, p. A192

Research output: Contribution to journal › Article › peer-review

Published

Beyond registration: measuring the public health potential of new treatments for Malaria in Africa.

Hughes, D., Lang, T., Hughes, D. A., Kanyok, T., Kengeya-Kayondo, J., Marsh, V., Haaland, A., Pirmohamed, M. & Winstanley, P., 1 Jan 2006, In: Lancet Infectious Diseases. 6, 1, p. 46-52

Research output: Contribution to journal › Article › peer-review

Published

Health economic aspects of patient non-compliance

Hughes, D., Hughes, D. A., Davies, M. (ed.) & Kermani, F. (ed.), 1 Jan 2006, Patient Compliance: Sweetening the Pill. 2006 ed. Gower Publishing, p. 23-40

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

Improving Outcomes for People with Brain and Other CNS Tumours: Analysis of the Potential Economic Impact of the Guidance.

Hughes, D., Linck, P., Priedane, E., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Improving Outcomes for People with Sarcoma: Analysis of the Potential Economic Impact of the Guidance.

Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Less is more: Medicines that require less frequent administration improve adherence, but are they better?

Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 3, p. 211-213

Research output: Contribution to journal › Article › peer-review

Published

Public funding of drugs for orphan diseases

Hughes, D. & Hughes, D. A., 1 Jan 2006.

Research output: Contribution to conference › Paper

Published

Rationing of drugs for rare diseases.

Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 4, p. 315-316

Research output: Contribution to journal › Article › peer-review

Published

Improving Outcomes for People with Skin Tumours including Melanoma: Analysis of the Potential Economic Impact of the Guidance.

Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 21 Feb 2006, Unknown.

Research output: Book/Report › Commissioned report

Published

Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

Research output: Contribution to conference › Paper

Published

Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.

Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300

Research output: Contribution to journal › Article › peer-review

Published

Health and economic outcomes: Why compliance matters

Hughes, D. & Hughes, D. A., 1 Apr 2006.

Research output: Contribution to conference › Paper

Published

Physchiatrist prescribing preferences and attitudes toward promotion

Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Apr 2006.

Research output: Contribution to conference › Paper

Published

Rationing of drugs for rare diseases

Hughes, D. & Hughes, D. A., 1 Apr 2006.

Research output: Contribution to conference › Paper

Published

Back to basics: what is the relationship between dose and duration of drug action?

Hughes, D. & Hughes, D. A., 1 May 2006.

Research output: Contribution to conference › Paper

Published

Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments

Hughes, D. & Hughes, D. A., 1 May 2006.

Research output: Contribution to conference › Paper

Published

Orphan drugs revisited: author's response.

Hughes, D. & Hughes, D. A., 1 May 2006, In: Quarterly Journal of Medicine. 99, 5, p. 350-351

Research output: Contribution to journal › Article › peer-review

Published

Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment

Hughes, D., Myles, S., Hughes, D. A., Longo, M. & Lisles, C., 1 Jun 2006.

Research output: Contribution to conference › Paper

Published

Prescription fee exemption research study

Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.

Research output: Contribution to conference › Paper

Published

Clinical and econnomic importance of completion of therapy in the treatment of LRTIs

Hughes, D. & Hughes, D. A., 1 Sept 2006.

Research output: Contribution to conference › Paper

Published

Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?

Hughes, D. & Hughes, D. A., 1 Nov 2006.

Research output: Contribution to conference › Paper

Published

AWMSG criteria for appraising new medicines.

Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Adverse drug reactions in economic evaluations

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

Research output: Contribution to journal › Article › peer-review

Published

All Wales Medicines Strategy Group Final Appraisal Report - Emtricitabine/tenofovir DF (Truvada)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Co-careldopa intestinal gel (Duodopa).

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Darunavir (Prezista)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Lymphoid blast CML and PH+ ALL.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Dexrazoxane (Savene)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Emtricitabine (Emtriva)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Idursulfase (Elaprase)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report – Tipranavir (Aptivus).

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A171

Research output: Contribution to journal › Article › peer-review

Published

Biological agents for the management of Crohn's disease in adults: A systematic review, meta-analysis and multiples treatment comparison

Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A147

Research output: Contribution to journal › Article › peer-review

Published

Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A23

Research output: Contribution to journal › Article › peer-review

Published

Feasibility, validity, and reliability of the Welsh version of the EQ-5D health status questionnaire

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A189

Research output: Contribution to journal › Article › peer-review

Published

Follow-up of cancer patients in primary care versus secondary care: systematic review.

Hughes, D., Lewis, R., Neal, R., Williams, N., France, B., Wilkinson, C., Hendry, M., Russell, D., Hughes, D. A., Russell, I. T., Stuart, N. S. & Weller, D., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Policy on ultra-orphan drugs.

Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Warfarin pharmacogenetics: Economic considerations.

Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

Research output: Contribution to journal › Article › peer-review

Published

When drugs don't work - Economic assessment of enhancing compliance with interventions supported by electronic monitoring devices.

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Pharmacoeconomics. 25, 8, p. 621-635

Research output: Contribution to journal › Article › peer-review

Published

Adverse drug reactions in economic evaluations

Hughes, D. & Hughes, D. A., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

Hughes, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial

Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Falls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people

Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

Hughes, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Non-compliance with antibiotic therapy for acute community infections: A global survey.

Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253

Research output: Contribution to journal › Article › peer-review

Published

Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer

Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.

Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685

Research output: Contribution to journal › Article › peer-review

Published

Adverse drug reactions: analysis by regulatory authorities and by economists

Hughes, D. & Hughes, D. A., 1 Apr 2007.

Research output: Contribution to conference › Paper

Published

A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Biological agents for the management of Crohn's disease in adults: a systematic review, meta-analysis and multiple treatment comparison

Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Quantitative risk-benefit analysis

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Adherence with HAART: pharmacoeconomic considerations

Hughes, D. & Hughes, D. A., 1 Jun 2007.

Research output: Contribution to conference › Paper

Published

Adverse drug reactions in economic evaluations

Hughes, D. & Hughes, D. A., 1 Jul 2007.

Research output: Contribution to conference › Paper

Published

A prototype agent-based model of antimalarial drug compliance

Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Cost of non-compliance and non-persistence with medications for diabetes mellitus

Hughes, D., Salas, M., Hughes, D. A., Lebmeier, M. & Vardeva, K., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?

Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

Research output: Contribution to journal › Article › peer-review

Published

Impact of the abolition of prescription charges in Wales: a multi-level modelling approach with application to time series dispensed rate data

Hughes, D., Alam, F., Myles, S., Hughes, D. A., Dunstan, F., Routledge, P. & Cohen, D., 1 Sept 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh version of the EQ-5D health status questionnaire.

Hughes, D. & Hughes, D. A., 1 Oct 2007, In: Quality of Life Research. 16, 8, p. 1419-1423

Research output: Contribution to journal › Article › peer-review

Published

Interventions that enhance medication compliance and persistence: Theoretical grounding, and economic assessment

Hughes, D., Hughes, D. A., Gwadry Sridhar, F., Elliott, R. & Cowell, W., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment

Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

The assessment, determinants & economics of medication compliance & persistence

Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

Research output: Contribution to journal › Article › peer-review

Published

Orphan drug treatments: economic considerations

Hughes, D. & Hughes, D. A., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study

Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial

Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.

Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65

Research output: Contribution to journal › Article › peer-review

Published

A Global Survey of Antibiotic Leftovers in the Outpatient Setting.

Hughes, D., Kardas, P., Pechere, J. C., Hughes, D. A. & Cornaglia, G., 1 Dec 2007, In: International Journal of Antimicrobial Agents. 30, 6, p. 530-536

Research output: Contribution to journal › Article › peer-review

Published

Public meetings of the NICE appraisals committee

Hughes, D. & Hughes, D. A., 1 Dec 2007.

Research output: Contribution to conference › Paper

Published

The pharmacokinetic profile of Warfarn: a systematic review

Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

Research output: Contribution to conference › Paper

Published

All Wales Medicines Strategy Group Final Appraisal Report - Abacavir 600mg/lamivudine 300mg (Kivexa) in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus infection in adults and adolescents from 12 years of age.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Alemtuzumab (MabCampath) for the treatment of patients with B-cell chronic lymphocytic leukaemia for whom fludarabine combination chemotherapy is not appropriate.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-naïve patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Buprenorphine/naloxone (Suboxone) as substitution treatment for opioid dependence.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Deferasirox (Exjade) for the treatment of chronic iron overload due to blood transfusions.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Docetaxel (Taxotere) for locally advanced squamous cell carcinoma of the head and neck.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Epoetin delta (Dynepo)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for STEMI.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for UA/NSTEMI.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Icatibant (Firazyr) for symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults (with C1-esterase-inhibitor deficiency).

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Lenalidomide (Revlimid) for multiple myeloma.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Pegfilgrastim (Neulasta) for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Raltegravir (Isentress) in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infection in treatment-experienced adult patients with evidence of HIV-1 replication despite ongoing antiretroviral therapy.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Rufinamide (Inovelon) for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS).

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Stiripentol (Diacomit) for use in conjunction with clobazam and valproate in patients with severe myoclonic epilepsy in infancy.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Teriparatide (Forsteo) for the treatment of osteoporosis in men at increased risk of fracture.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Topotecan (Hycamtin®) for Small Cell Lung Carcinoma.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Trabectedin (Yondelis) for advanced soft tissue sarcoma.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Ziconotide (Prialt) for the intrathecal treatment of severe, chronic pain.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Charitable contributions to funding cancer services for children and young people in England and Wales

Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2008, In: Journal of Child Health Care. 12, 2, p. 156-168

Research output: Contribution to journal › Article › peer-review

Published

Chiral chromatography: Costs of chiral switching.

Hughes, D. & Hughes, D. A., 1 Jan 2008, In: Pharmaceutical Journal. 281, p. 213

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness considerations in pharmacogenetics.

Hughes, D. & Hughes, D. A., 1 Jan 2008.

Research output: Contribution to conference › Paper

Published

Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Effects of the abolition of prescription charges in Wales: a preliminary analysis.

Hughes, D., Cohen, D., Alam, M. F., Hughes, D. A., Dunstan, F. & Routledge, P., 1 Jan 2008, In: International Journal of Pharmacy Practice. 16, Supplement 1, p. A39

Research output: Contribution to journal › Article › peer-review

Published

Integrating compliance and persistence in health economics models

Hughes, D. & Hughes, D. A., 1 Jan 2008.

Research output: Contribution to conference › Paper

Published

Investigating factors influencing user choices to visit either general practioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment.

Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.

Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Understanding medication compliance and persistence from an economics perspective

Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Jan 2008, In: Value in Health. 11, 4, p. 600-610

Research output: Contribution to journal › Article › peer-review

Published

Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing

Hughes, D. & Hughes, D. A., 1 Feb 2008.

Research output: Contribution to conference › Paper

Published

From efficacy to cost-effectiveness: Impact of patient compliance

Hughes, D. & Hughes, D. A., 1 Feb 2008.

Research output: Contribution to conference › Paper

Published

Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments – piloting a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Mar 2008

Research output: Non-textual form › Web publication/site

Published

Statistical comments are unfounded.

Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

Research output: Contribution to journal › Article › peer-review

Published

The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data

Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Effects of the abolition of prescription charges in Wales: A preliminary analysis

Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Costs of non-compliance to antipsychotic medications among patients with schizophrenia.

Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.

Research output: Contribution to conference › Paper

Published

The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.

Research output: Contribution to conference › Paper

Published

Economic considerations for pharmacogenetic testing

Hughes, D. & Hughes, D. A., 1 Jun 2008.

Research output: Contribution to conference › Paper

Published

Medicines concordance and game theory.

Hughes, D. & Hughes, D. A., 1 Oct 2008, In: British Journal of Clinical Pharmacology. 66, 4, p. 577

Research output: Contribution to journal › Article › peer-review

Published

Impact of the abolition of the prescription charge in Wales

Hughes, D. & Hughes, D. A., 1 Nov 2008.

Research output: Contribution to conference › Paper

Published

Methodological Issues in the literature on costs of non-compliance in chronic diseases.

Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008, In: Value in Health. 11, 6, p. A571-A572

Research output: Contribution to journal › Article › peer-review

Published

Methodological issues in the literature on costs of non-compliance in chronic diseases

Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

Research output: Contribution to conference › Paper

Published

The all wales medicines strategy group: assessments and appraisals

Hughes, D. & Hughes, D. A., 1 Nov 2008.

Research output: Contribution to conference › Paper

Published

Estimation of the impact of noncompliance on pharmacokinetics: an analysis of the influence of dosing regimens

Hughes, D. & Hughes, D. A., 1 Dec 2008, In: British Journal of Clinical Pharmacology. 65, 6, p. 871-878

Research output: Contribution to journal › Article › peer-review

Published

A systematic review and empirical analysis of the relation between dose and duration of drug action.

Hughes, D., Hughes, D. A. & Aronson, J. K., 1 Jan 2009, p. TP40.

Research output: Contribution to conference › Paper

Published

All Wales Medicines Strategy Group Final Appraisal Report - Ambrisentan (Volibris) for pulmonary arterial hypertension.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Anidulafungin (Ecalta) for the treatment of invasive candidiasis in adult non-neutropenic patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Maraviroc (Celsentri) for treatment-experienced adults infected only with CCR5-tropic HIV-1.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Tacrolimus (Advagraf) for the prophylaxis of transplant rejection in adult kidney or liver allograft recipients and the treatment of allograft rejection resistant to treatment with other immunosuppressive medicinal products in adult patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Assessment, Determinants & Economics of Medication Compliance & Persistence Forum.

Hughes, D., Hughes, D. A., Gwadry-Sridhar, F. & Manias, E., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Comparisons between the medication possession ratio (MPR) and gaps measures of medication compliance: are we selling ourselves short by relying on the MPR?

Hughes, D., Nichol, M., Manias, E., Hughes, D. A. & Schabert, V. F., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Drug evaluation and pharmocoeconomics.

Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (ed.), Rees, J. A. (ed.) & Smith, I. (ed.), 1 Jan 2009, Pharmaceutical Practice: 4th Edition.. 2009 ed. Churchill Livingstone, p. 185-198

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

Economic evaluation of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Engaging with the MRC Methodology Hubs – NWHTMR.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Impact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.

Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Impact of the abolition of the prescription charge in Wales.

Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009, p. O41.

Research output: Contribution to conference › Paper

Published

Impact of the abolition of the prescription charge in Wales.

Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Impact of the abolition of the prescription charge in Wales.

Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

The economics of evergreening.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

A Framework for Planning and Critiquing Medication Compliance and Persistence Research Using Prospective Study Designs.

Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Zhang, Y., Roy, A., Yu-Isenberg, K., Hughes, D. A. & Nichol, M. B., 1 Feb 2009, In: Clinical Therapeutics. 31, 2, p. 421-435

Research output: Contribution to journal › Article › peer-review

Published

Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review

Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723

Research output: Contribution to journal › Article › peer-review

Published

Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

Research output: Contribution to journal › Article › peer-review

Published

Patients' and healthcare professionals' views of cancer follow-up: systematic review

Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259

Research output: Contribution to journal › Article › peer-review

Published

Follow-up of cancer in primary care versus secondary care: systematic review

Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Jul 2009, In: British Journal of General Practice. 59, 564, p. e234-e247

Research output: Contribution to journal › Article › peer-review

Published

Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.

Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.

Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Aug 2009, In: Alimentary Pharmacology and Therapeutics. 30, 3, p. 265-274

Research output: Contribution to journal › Article › peer-review

Published

Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.

Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, M. E., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 26 Aug 2009, In: Malaria Journal. 8, p. 204

Research output: Contribution to journal › Article › peer-review

Published

Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.

Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Sept 2009, In: Value in Health. 12, 6, p. 915-922

Research output: Contribution to journal › Article › peer-review

Published

Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

Research output: Contribution to journal › Article › peer-review

Published

Pharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.

Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Oct 2009, In: Clinical Medicine. 9, 5, p. 490-492

Research output: Contribution to journal › Article › peer-review

Published

Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

Research output: Contribution to conference › Paper

Published

NICE and new: appraising innovation.

Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493

Research output: Contribution to journal › Article › peer-review

Published

New drugs for old: disinvestment and NICE.

Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572

Research output: Contribution to journal › Article › peer-review

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Mar 2010, In: Clinical Pharmacology and Therapeutics. 87, 3, p. 257-261

Research output: Contribution to journal › Article › peer-review

Published

A systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives

Hughes, D., Verhoef, T. I., Redekop, W. K., Darba, J., Geitona, M., Hughes, D. A., Siebert, U., de Boer, A., Maitland-van der Zee, A. H., Barallon, R., Briz, M., Daly, A., Haschke-Becher, E., Kamali, F., Kirchheiner, J., Manolopoulos, V. G., Pirmohamed, M., Rosendaal, F. R., van Schie, R. M. & Wadelius, M., 1 Jul 2010, In: Pharmacogenomics. 11, 7, p. 989-1002

Research output: Contribution to journal › Article › peer-review

Published

Abolition of prescription copayments in Wales: an observational study on dispensing rates.

Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

Research output: Contribution to journal › Article › peer-review

Published

Is exercise effective in promoting mental well-being in older age? A systematic review.

Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

Research output: Contribution to journal › Article › peer-review

Published

From NCE to NICE: the role of pharmacoeconomics

Hughes, D. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 317-319

Research output: Contribution to journal › Article › peer-review

Published

Generic and therapeutic substitutions in the UK: are they a good thing?

Hughes, D., Duerden, M. G. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 335-341

Research output: Contribution to journal › Article › peer-review

Published

The problem of orphan drugs

Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

Research output: Contribution to journal › Article › peer-review

Published

Abolition of prescription charges in Wales: the impact on medicines use in those who used to pay

Hughes, D., Groves, S., Cohen, D., Alam, M. F., Dunstan, F. D., Routledge, P. A., Hughes, D. A. & Myles, S., 1 Dec 2010, In: International Journal of Pharmacy Practice. 18, 6, p. 332-340

Research output: Contribution to journal › Article › peer-review

Published

Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program

Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872

Research output: Contribution to journal › Article › peer-review

Published

Involving colleagues can be challenging

Fargher, E. & Hughes, D., 2 Apr 2011, In: Pharmaceutical Journal. 286, p. 404

Research output: Contribution to journal › Letter › peer-review

Published

Value-Based Pricing: Incentive for Innovation or Zero Net Benefit?

Hughes, D. & Hughes, D. A., 1 Sept 2011, In: Pharmacoeconomics. 29, 9, p. 731-735

Research output: Contribution to journal › Article › peer-review

Published

Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

Research output: Contribution to journal › Article › peer-review

Published

HTAs and rare diseases: How to assess their cost-effectiveness

Hughes, D., Phillips, C. J. & Hughes, D. A., 1 Nov 2011, In: Pharmaceuticals Policy and Law. 13, 3-4, p. 161-165

Research output: Contribution to journal › Article › peer-review

Published

The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76

Research output: Contribution to journal › Article › peer-review

Published

Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.

Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Mar 2012, In: Pharmacoeconomics.

Research output: Contribution to journal › Article › peer-review

Published

A Risk–Benefit Assessment of Prasugrel, Clopidogrel, and Genotype-Guided Therapy in Patients Undergoing Percutaneous Coronary Intervention

Hughes, D., Guzauskas, G. F., Hughes, D. A., Bradley, S. M. & Veenstra, D. L., 28 Mar 2012, In: Clinical Pharmacology and Therapeutics.

Research output: Contribution to journal › Article › peer-review

Published

Defining rewardable innovation in drug therapy

Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

Research output: Contribution to journal › Article › peer-review

Published

An explanatory randomised controlled trial of a nurse-led, consultation-based intervention to support patients with adherence to taking glucose lowering medication for type 2 diabetes

Hughes, D., Farmer, A., Hardeman, W., Hughes, D. A., Prevost, A. T., Kim, Y., Craven, A., Oke, J., Boase, S., Selwood, M., Kellar, I., Graffy, J., Griffin, S., Sutton, S. & Kinmonth, A. L., 5 Apr 2012, In: BMC Family Practice. 13, 30

Research output: Contribution to journal › Article › peer-review

Published

A new taxonomy for describing and defining adherence to medications

Holmes, E. A., Hughes, D., Morrison, V. L., Vrijens, B., De Geest, S., Hughes, D. A., Prezemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K. & Urquhart, J., 1 May 2012, In: British Journal of Clinical Pharmacology. 73, 5, p. 691-705

Research output: Contribution to journal › Article › peer-review

Published

The development of a QALY measure for epilepsy: NEWQOL-6D

Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

Research output: Contribution to journal › Article › peer-review

Published

An agenda for UK clinical pharmacology Pharmacoeconomics

Hughes, D. & Hughes, D. A., 1 Jun 2012, In: British Journal of Clinical Pharmacology. 73, 6, p. 968-972

Research output: Contribution to journal › Article › peer-review

Published

Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design

DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655

Research output: Contribution to journal › Article › peer-review

Published

Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

Research output: Contribution to journal › Article › peer-review

Published

Reimbursement Decisions of the All Wales Medicines Strategy Group

Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794

Research output: Contribution to journal › Article › peer-review

Published

Challenges in the Development and Reimbursement of Personalized Medicine—Payer and Manufacturer Perspectives and Implications for Health Economics and Outcomes Research: A Report of the ISPOR Personalized Medicine Special Interest Group

Hughes, D., Faulkner, E., Annemans, L., Garrison, L., Helfand, M., Holtorf, A. P., Hornberger, J., Hughes, D. A., Li, T., Malone, D., Payne, K., Siebert, U., Towse, A., Veenstra, D. & Watkins, J., 1 Dec 2012, In: Value in Health. 15, 8, p. 1162-1171

Research output: Contribution to journal › Article › peer-review

Research Portal

Professor Dyfrig Hughes

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