Dyfrig Hughes - Research outputs

Hughes, D., Lewis, R., Neal, R., Williams, N., France, B., Wilkinson, C., Hendry, M., Russell, D., Hughes, D. A., Russell, I. T., Stuart, N. S. & Weller, D., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Policy on ultra-orphan drugs.

Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Warfarin pharmacogenetics: Economic considerations.

Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

Research output: Contribution to journal › Article › peer-review

Published

When drugs don't work - Economic assessment of enhancing compliance with interventions supported by electronic monitoring devices.

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Pharmacoeconomics. 25, 8, p. 621-635

Research output: Contribution to journal › Article › peer-review

Published

Adverse drug reactions in economic evaluations

Hughes, D. & Hughes, D. A., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

Hughes, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial

Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Falls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people

Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

Hughes, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Non-compliance with antibiotic therapy for acute community infections: A global survey.

Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253

Research output: Contribution to journal › Article › peer-review

Published

Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer

Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.

Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685

Research output: Contribution to journal › Article › peer-review

Published

Adverse drug reactions: analysis by regulatory authorities and by economists

Hughes, D. & Hughes, D. A., 1 Apr 2007.

Research output: Contribution to conference › Paper

Published

A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Biological agents for the management of Crohn's disease in adults: a systematic review, meta-analysis and multiple treatment comparison

Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Quantitative risk-benefit analysis

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Adherence with HAART: pharmacoeconomic considerations

Hughes, D. & Hughes, D. A., 1 Jun 2007.

Research output: Contribution to conference › Paper

Published

Adverse drug reactions in economic evaluations

Hughes, D. & Hughes, D. A., 1 Jul 2007.

Research output: Contribution to conference › Paper

Published

A prototype agent-based model of antimalarial drug compliance

Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Cost of non-compliance and non-persistence with medications for diabetes mellitus

Hughes, D., Salas, M., Hughes, D. A., Lebmeier, M. & Vardeva, K., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?

Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

Research output: Contribution to journal › Article › peer-review

Published

Impact of the abolition of prescription charges in Wales: a multi-level modelling approach with application to time series dispensed rate data

Hughes, D., Alam, F., Myles, S., Hughes, D. A., Dunstan, F., Routledge, P. & Cohen, D., 1 Sept 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh version of the EQ-5D health status questionnaire.

Hughes, D. & Hughes, D. A., 1 Oct 2007, In: Quality of Life Research. 16, 8, p. 1419-1423

Research output: Contribution to journal › Article › peer-review

Published

Interventions that enhance medication compliance and persistence: Theoretical grounding, and economic assessment

Hughes, D., Hughes, D. A., Gwadry Sridhar, F., Elliott, R. & Cowell, W., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment

Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

The assessment, determinants & economics of medication compliance & persistence

Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

Research output: Contribution to journal › Article › peer-review

Published

Orphan drug treatments: economic considerations

Hughes, D. & Hughes, D. A., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study

Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial

Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.

Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65

Research output: Contribution to journal › Article › peer-review

Published

A Global Survey of Antibiotic Leftovers in the Outpatient Setting.

Hughes, D., Kardas, P., Pechere, J. C., Hughes, D. A. & Cornaglia, G., 1 Dec 2007, In: International Journal of Antimicrobial Agents. 30, 6, p. 530-536

Research output: Contribution to journal › Article › peer-review

Published

Public meetings of the NICE appraisals committee

Hughes, D. & Hughes, D. A., 1 Dec 2007.

Research output: Contribution to conference › Paper

Published

The pharmacokinetic profile of Warfarn: a systematic review

Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

Research output: Contribution to conference › Paper

Published

All Wales Medicines Strategy Group Final Appraisal Report - Abacavir 600mg/lamivudine 300mg (Kivexa) in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus infection in adults and adolescents from 12 years of age.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Alemtuzumab (MabCampath) for the treatment of patients with B-cell chronic lymphocytic leukaemia for whom fludarabine combination chemotherapy is not appropriate.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-naïve patients.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Buprenorphine/naloxone (Suboxone) as substitution treatment for opioid dependence.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Deferasirox (Exjade) for the treatment of chronic iron overload due to blood transfusions.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Docetaxel (Taxotere) for locally advanced squamous cell carcinoma of the head and neck.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Epoetin delta (Dynepo)

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for STEMI.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for UA/NSTEMI.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Icatibant (Firazyr) for symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults (with C1-esterase-inhibitor deficiency).

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Lenalidomide (Revlimid) for multiple myeloma.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Pegfilgrastim (Neulasta) for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Raltegravir (Isentress) in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infection in treatment-experienced adult patients with evidence of HIV-1 replication despite ongoing antiretroviral therapy.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Rufinamide (Inovelon) for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS).

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Stiripentol (Diacomit) for use in conjunction with clobazam and valproate in patients with severe myoclonic epilepsy in infancy.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Teriparatide (Forsteo) for the treatment of osteoporosis in men at increased risk of fracture.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Topotecan (Hycamtin®) for Small Cell Lung Carcinoma.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Trabectedin (Yondelis) for advanced soft tissue sarcoma.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

All Wales Medicines Strategy Group Final Appraisal Report - Ziconotide (Prialt) for the intrathecal treatment of severe, chronic pain.

Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Charitable contributions to funding cancer services for children and young people in England and Wales

Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2008, In: Journal of Child Health Care. 12, 2, p. 156-168

Research output: Contribution to journal › Article › peer-review

Published

Chiral chromatography: Costs of chiral switching.

Hughes, D. & Hughes, D. A., 1 Jan 2008, In: Pharmaceutical Journal. 281, p. 213

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness considerations in pharmacogenetics.

Hughes, D. & Hughes, D. A., 1 Jan 2008.

Research output: Contribution to conference › Paper

Published

Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Effects of the abolition of prescription charges in Wales: a preliminary analysis.

Hughes, D., Cohen, D., Alam, M. F., Hughes, D. A., Dunstan, F. & Routledge, P., 1 Jan 2008, In: International Journal of Pharmacy Practice. 16, Supplement 1, p. A39

Research output: Contribution to journal › Article › peer-review

Published

Integrating compliance and persistence in health economics models

Hughes, D. & Hughes, D. A., 1 Jan 2008.

Research output: Contribution to conference › Paper

Published

Investigating factors influencing user choices to visit either general practioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment.

Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.

Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Understanding medication compliance and persistence from an economics perspective

Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Jan 2008, In: Value in Health. 11, 4, p. 600-610

Research output: Contribution to journal › Article › peer-review

Published

Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing

Hughes, D. & Hughes, D. A., 1 Feb 2008.

Research output: Contribution to conference › Paper

Published

From efficacy to cost-effectiveness: Impact of patient compliance

Hughes, D. & Hughes, D. A., 1 Feb 2008.

Research output: Contribution to conference › Paper

Published

Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments – piloting a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Mar 2008

Research output: Non-textual form › Web publication/site

Published

Statistical comments are unfounded.

Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

Research output: Contribution to journal › Article › peer-review

Published

The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data

Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Effects of the abolition of prescription charges in Wales: A preliminary analysis

Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Costs of non-compliance to antipsychotic medications among patients with schizophrenia.

Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.

Research output: Contribution to conference › Paper

Published

The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.

Research output: Contribution to conference › Paper

Published

Economic considerations for pharmacogenetic testing

Hughes, D. & Hughes, D. A., 1 Jun 2008.

Research output: Contribution to conference › Paper

Published

Medicines concordance and game theory.

Hughes, D. & Hughes, D. A., 1 Oct 2008, In: British Journal of Clinical Pharmacology. 66, 4, p. 577

Research output: Contribution to journal › Article › peer-review

Published

Impact of the abolition of the prescription charge in Wales

Hughes, D. & Hughes, D. A., 1 Nov 2008.

Research output: Contribution to conference › Paper

Published

Methodological Issues in the literature on costs of non-compliance in chronic diseases.

Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008, In: Value in Health. 11, 6, p. A571-A572

Research output: Contribution to journal › Article › peer-review

Published