Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
![](https://research.bangor.ac.uk/portal/files/28327363/Dyfrig_Hughes.jpg)
- Paper › Research › Not peer-reviewed
- Published
Biosimilars: Evidential standards for health technology assessment.
Hughes, D. & Hughes, D. A., 1 Jan 2009.Research output: Contribution to conference › Paper
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Clinical and econnomic importance of completion of therapy in the treatment of LRTIs
Hughes, D. & Hughes, D. A., 1 Sept 2006.Research output: Contribution to conference › Paper
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Comparisons between the medication possession ratio (MPR) and gaps measures of medication compliance: are we selling ourselves short by relying on the MPR?
Hughes, D., Nichol, M., Manias, E., Hughes, D. A. & Schabert, V. F., 1 Jan 2009.Research output: Contribution to conference › Paper
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Cost of non-compliance and non-persistence with medications for diabetes mellitus
Hughes, D., Salas, M., Hughes, D. A., Lebmeier, M. & Vardeva, K., 1 Aug 2007.Research output: Contribution to conference › Paper
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Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.Research output: Contribution to conference › Paper
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Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.Research output: Contribution to conference › Paper
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Cost-effectiveness considerations in pharmacogenetics.
Hughes, D. & Hughes, D. A., 1 Jan 2008.Research output: Contribution to conference › Paper
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Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease
Hughes, D. & Hughes, D. A., 1 Nov 2003.Research output: Contribution to conference › Paper
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Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease
Hughes, D. & Hughes, D. A., 1 Nov 2003.Research output: Contribution to conference › Paper
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Costs of non-compliance to antipsychotic medications among patients with schizophrenia.
Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.Research output: Contribution to conference › Paper
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Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?
Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.Research output: Contribution to conference › Paper
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Drug compliance and pharmaceconomics
Hughes, D. & Hughes, D. A., 1 Dec 2003.Research output: Contribution to conference › Paper
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Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing
Hughes, D. & Hughes, D. A., 1 Feb 2008.Research output: Contribution to conference › Paper
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Economic considerations for pharmacogenetic testing
Hughes, D. & Hughes, D. A., 1 Jun 2008.Research output: Contribution to conference › Paper
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Economic evaluation during early (phase II) trials
Hughes, D. & Hughes, D. A., 1 Nov 2002.Research output: Contribution to conference › Paper
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Economic evaluation of infliximab and adalimumab for Crohn's disease.
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Jan 2009.Research output: Contribution to conference › Paper
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Economic evaluation of on-demand maintenance therapy with proton pump inhibitors in patients with symptomatic gastroesophageal reflux disease - a Monte-Carlo analysis for Italy
Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Oct 2004.Research output: Contribution to conference › Paper
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Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial
Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.Research output: Contribution to conference › Paper
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Effects of the abolition of prescription charges in Wales: A preliminary analysis
Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.Research output: Contribution to conference › Paper
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Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design
Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.Research output: Contribution to conference › Paper
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Empirical analysis of the relationship between dose and duration of drug action
Hughes, D. & Hughes, D. A., 1 Jun 2005.Research output: Contribution to conference › Paper
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Engaging with the MRC Methodology Hubs – NWHTMR.
Hughes, D. & Hughes, D. A., 1 Jan 2009.Research output: Contribution to conference › Paper
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Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.
Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.Research output: Contribution to conference › Paper
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Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment
Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 May 2007.Research output: Contribution to conference › Paper
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Falls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people
Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Mar 2007.Research output: Contribution to conference › Paper
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Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire
Hughes, D. & Hughes, D. A., 1 May 2007.Research output: Contribution to conference › Paper
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Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire
Hughes, D., 1 Mar 2007.Research output: Contribution to conference › Paper
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From efficacy to cost-effectiveness: Impact of patient compliance
Hughes, D. & Hughes, D. A., 1 Feb 2008.Research output: Contribution to conference › Paper
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From efficacy to cost-effectiveness: accounting for non-compliance in pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 May 2002.Research output: Contribution to conference › Paper
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From efficacy to effectiveness and cost-effectiveness: modelling possibilities
Hughes, D. & Hughes, D. A., 1 Nov 2004.Research output: Contribution to conference › Paper
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Health and economic outcomes: Why compliance matters
Hughes, D. & Hughes, D. A., 1 Apr 2006.Research output: Contribution to conference › Paper
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Impact of non-compliance on the clinical and cost-effectiveness of statins
Hughes, D. & Hughes, D. A., 1 Nov 2001.Research output: Contribution to conference › Paper
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Impact of non-compliance on the cost-effectiveness of pharmaceuticals
Hughes, D. & Hughes, D. A., 1 Nov 2002.Research output: Contribution to conference › Paper
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Impact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.
Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Jan 2009.Research output: Contribution to conference › Paper
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Impact of the abolition of prescription charges in Wales: a multi-level modelling approach with application to time series dispensed rate data
Hughes, D., Alam, F., Myles, S., Hughes, D. A., Dunstan, F., Routledge, P. & Cohen, D., 1 Sept 2007.Research output: Contribution to conference › Paper
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Impact of the abolition of the prescription charge in Wales
Hughes, D. & Hughes, D. A., 1 Nov 2008.Research output: Contribution to conference › Paper
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Impact of the abolition of the prescription charge in Wales.
Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.Research output: Contribution to conference › Paper
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Impact of the abolition of the prescription charge in Wales.
Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.Research output: Contribution to conference › Paper
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Impact of the abolition of the prescription charge in Wales.
Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009, p. O41.Research output: Contribution to conference › Paper
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Incorporating measures of compliance and persistence in pharmacoeconomic evaluations
Hughes, D., Hughes, D. A. & Cowell, W., 1 Nov 2005.Research output: Contribution to conference › Paper
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Integrating compliance and persistence in health economics models
Hughes, D. & Hughes, D. A., 1 Jan 2008.Research output: Contribution to conference › Paper
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Interventions that enhance medication compliance and persistence: Theoretical grounding, and economic assessment
Hughes, D., Hughes, D. A., Gwadry Sridhar, F., Elliott, R. & Cowell, W., 1 Oct 2007.Research output: Contribution to conference › Paper
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Introduction to pharmaeconomics
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments
Hughes, D. & Hughes, D. A., 1 May 2006.Research output: Contribution to conference › Paper
- Published
Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment
Hughes, D., Myles, S., Hughes, D. A., Longo, M. & Lisles, C., 1 Jun 2006.Research output: Contribution to conference › Paper
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Methodological issues in the literature on costs of non-compliance in chronic diseases
Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.Research output: Contribution to conference › Paper
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Modelling changes in first line antimalarial therapy
Hughes, D. & Hughes, D. A., 1 Sept 2003.Research output: Contribution to conference › Paper
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Orphan drug treatments: economic considerations
Hughes, D. & Hughes, D. A., 1 Nov 2007.Research output: Contribution to conference › Paper
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Patient compliance and persistence with prescribed medication: Measurement and health economic impact
Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 May 2004.Research output: Contribution to conference › Paper
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Patient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Nov 2002.Research output: Contribution to conference › Paper
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Patient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Oct 2001.Research output: Contribution to conference › Paper
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Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment
Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.Research output: Contribution to conference › Paper
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Pharmacoeconomic models that incorporate non-compliance
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics appraisals by the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Apr 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics of pharmacogenetic testing: azathioprine
Hughes, D., McAllister, R. & Hughes, D. A., 1 Apr 2004.Research output: Contribution to conference › Paper
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Pharmacokinetics, patient compliance and pharmaeconomics
Hughes, D. & Hughes, D. A., 1 Jun 2005.Research output: Contribution to conference › Paper
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Pharmacometric analysis of duration of drug action: implications for improved forgiveness to medication non-compliance
Hughes, D., Hughes, D. A. & Walley, T., 1 Sept 2001.Research output: Contribution to conference › Paper
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Physchiatrist prescribing preferences and attitudes toward promotion
Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Apr 2006.Research output: Contribution to conference › Paper
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Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study
Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.Research output: Contribution to conference › Paper
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Pragmatic trials - design features and implications for clinical decision making
Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Aug 2000.Research output: Contribution to conference › Paper
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Prescription fee exemption research study
Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Jul 2005.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Jan 2006.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Nov 2005.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Nov 2005.Research output: Contribution to conference › Paper
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Public meetings of the NICE appraisals committee
Hughes, D. & Hughes, D. A., 1 Dec 2007.Research output: Contribution to conference › Paper
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Quantitative risk-benefit analysis
Hughes, D. & Hughes, D. A., 1 May 2007.Research output: Contribution to conference › Paper
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Rationing of drugs for rare diseases
Hughes, D. & Hughes, D. A., 1 Apr 2006.Research output: Contribution to conference › Paper
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Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer
Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.Research output: Contribution to conference › Paper
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The all wales medicines strategy group: assessments and appraisals
Hughes, D. & Hughes, D. A., 1 Nov 2008.Research output: Contribution to conference › Paper
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The assessment, determinants & economics of medication compliance & persistence
Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Oct 2007.Research output: Contribution to conference › Paper
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The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data
Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.Research output: Contribution to conference › Paper
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The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data
Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.Research output: Contribution to conference › Paper
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The economics of evergreening.
Hughes, D. & Hughes, D. A., 1 Jan 2009.Research output: Contribution to conference › Paper
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The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial
Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.Research output: Contribution to conference › Paper
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The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies
Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Nov 2000.Research output: Contribution to conference › Paper
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The pharmacokinetic profile of Warfarn: a systematic review
Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.Research output: Contribution to conference › Paper
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The population pharmacokinetics of lapdap
Hughes, D., Ward, S., Simpson, J., Aarons, L., Szwandt, S. & Hughes, D. A., 1 Nov 2002.Research output: Contribution to conference › Paper
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Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?
Hughes, D. & Hughes, D. A., 1 Nov 2006.Research output: Contribution to conference › Paper
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Use of PK-PD modelling to predict the impact of non-compliance
Hughes, D. & Hughes, D. A., 1 Nov 2003.Research output: Contribution to conference › Paper
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What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?
Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.Research output: Contribution to conference › Paper
- Chapter › Research › Peer-reviewed
- Published
Review of resource-use measures in UK economic evaluations
Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
- Chapter › Research › Not peer-reviewed
- Published
Approaches to pharmacoeconomic analysis
Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 101-126Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Drug evaluation and pharmocoeconomics.
Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (ed.), Rees, J. A. (ed.) & Smith, I. (ed.), 1 Jan 2009, Pharmaceutical Practice: 4th Edition.. 2009 ed. Churchill Livingstone, p. 185-198Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Health economic aspects of patient non-compliance
Hughes, D., Hughes, D. A., Davies, M. (ed.) & Kermani, F. (ed.), 1 Jan 2006, Patient Compliance: Sweetening the Pill. 2006 ed. Gower Publishing, p. 23-40Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Modelling in health economics
Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 141-154Research output: Chapter in Book/Report/Conference proceeding › Chapter
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The future challenges
Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Meeting Abstract › Research › Peer-reviewed
- Published
Cost effectiveness analysis of treatments for children with uncontrolled asthma symptoms despite taking inhaled corticosteroids
Culeddu, G., Sinha, I., Donegan, S., Maden, M., Cividini, S., Rose, K., Fulton, O., Turner, S., Tudor-Smith, C. & Hughes, D., 27 Oct 2023, In: European Respiratory Journal. 62 , Supplement 67, PA 523.Research output: Contribution to journal › Meeting Abstract › peer-review
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Patient preferences for outcomes in clinical trials: implications for medicines optimization
Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
- Editorial › Research › Peer-reviewed
- Published
Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline
de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Jun 2019, In: Journal of Cardiovascular Nursing. 34, 3, p. 199-200Research output: Contribution to journal › Editorial › peer-review
- Published
Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)
de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.Research output: Contribution to journal › Editorial › peer-review
- Published
Medication adherence research comes of age
Wright, D. F. B., Sinnappah, K. A. & Hughes, D., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1914-1917Research output: Contribution to journal › Editorial › peer-review
- Published
Medication adherence – key considerations for clinical pharmacologists
Hughes, D., Apr 2020, In: British Journal of Clinical Pharmacology. 86, 4, p. 628-629 2 p.Research output: Contribution to journal › Editorial › peer-review
- Comment/debate › Research › Peer-reviewed
- Published
Challenges for economic evaluation of strategies to contain antimicrobial resistance
Holmes, E. & Hughes, D., 27 Sept 2019, In: Antibiotics. 8, 4, 8 p., 166.Research output: Contribution to journal › Comment/debate › peer-review
- Published
Pharmacogenomics spotlight commentary: From the United Kingdom to global populations
Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.Research output: Contribution to journal › Comment/debate › peer-review
- Comment/debate › Research › Not peer-reviewed
- Published
Cost-effectiveness of HLA-B*15:02 screening in Malaysia
Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905Research output: Contribution to journal › Comment/debate
- Letter › Research › Peer-reviewed
- Published
2016 Prof. John Urquhart Obituary
Breckenridge, A. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 573Research output: Contribution to journal › Letter › peer-review
- Published
Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.
Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25Research output: Contribution to journal › Letter › peer-review
- Published
Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review
Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673Research output: Contribution to journal › Letter › peer-review